Unveiling the Therapeutic Wealth of Eclipta Prostrata: Ethnobotany, Bioactive Compounds, and Biomedical Relevance

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Vol. 13 No. 3 (2025): 2025 Volume -13 - Issue 3

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July 25, 2025
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Unveiling the Therapeutic Wealth of Eclipta Prostrata: Ethnobotany, Bioactive Compounds, and Biomedical Relevance

G. Sumithra
Lecturer, Department of Pharmacognosy, KMCH College of Pharmacy, Coimbatore, Tamil Nadu, India.
M. Navaneetha Krishnan
Research Scholar, Department of Pharmacognosy, College of Pharmacy, Madurai Medical College, Madurai, Tamil Nadu, India.
S. Nandhini
Research Scholar, Department of Pharmacognosy, College of Pharmacy, Madurai Medical College, Madurai, Tamil Nadu, India.
P.V. Agalya Gayathri
Research Scholar, Department of Pharmacognosy, College of Pharmacy, Madurai Medical College, Madurai, Tamil Nadu, India.
B. Yuvan Karthik
Research Scholar, Department of Pharmaceutical Chemistry, College of Pharmacy, Madurai Medical College, Madurai, Tamil Nadu, India.
G. Subitcha Jabakani
Research Scholar, Department of Pharmaceutical Chemistry, College of Pharmacy, Madurai Medical College, Madurai, Tamil Nadu, India.

Corresponding Author(s) : M. Navaneetha Krishnan

navee3136@gmail.com

International Journal of Allied Medical Sciences and Clinical Research, Vol. 13 No. 3 (2025): 2025 Volume -13 - Issue 3

Abstract

Eclipta prostrata (L.) L., also referred to as Eclipta alba, is a common medicinal herb that is a member of the Asteraceae family. It is well known for its ability to heal respiratory, skin, and liver illnesses as well as to encourage hair growth. It has long been prized in many ethnomedical systems. The current understanding of E. prostrata's botanical description, ethnomedical applications, phytochemical makeup, and range of pharmacological activity is compiled in this paper. The plant has a wide range of bioactive substances, including as alkaloids (ecliptine), triterpenoid saponins (eclalbasaponins), flavonoids (e.g., luteolin), phenolic compounds, and coumestans (e.g., wedelolactone). Its powerful anti-inflammatory, antioxidant, antidiabetic, hepatoprotective, anticancer, antiobesity, osteogenic, neuroprotective, immunomodulatory, antiulcer, and antibacterial qualities have been emphasized in recent research. Certain phytoconstituents are thought to be responsible for the therapeutic benefits via working via ERK/STAT1, AMPK/PGC-1α, NF-κB, and METTL3-mediated RNA methylation. The review supports the plant's incorporation into contemporary pharmaceutical formulations and highlights its promising role in evidence-based therapy.

Keywords

Eclipta prostrata Eclipta alba Wedelolactone Coumestans Ethnopharmacology Phytochemistry Traditional medicine Herbal therapeutics
1.
G. Sumithra, M. Navaneetha Krishnan, S. Nandhini, P.V. Agalya Gayathri, B. Yuvan Karthik, G. Subitcha Jabakani. Unveiling the Therapeutic Wealth of Eclipta Prostrata: Ethnobotany, Bioactive Compounds, and Biomedical Relevance. Int. J. of Allied Med. Sci. and Clin. Res. [Internet]. 2025 Jul. 25 [cited 2025 Sep. 20];13(3):463-9. Available from: https://ijamscr.com/ijamscr/article/view/1650
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