Salivary Gland Lesions – a Histopathological Study in a Tertiary Care Centre
Corresponding Author(s) : Dr. Natasha Patel
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 9 No. 2 (2021): 2021 Volume - 9 Issue - 2
Abstract
Introduction: Salivary gland lesions constitute <1% of all tumors and about less than 4% of all epithelial neoplasm in head and neck region and are therefore relatively rare. These tumors not uncommonly pose problems in diagnosis due to rarity, broad morphologic spectrum and morphologic overlap among the different tumor types .Proper diagnosis of malignant tumors with accurate staging is very important in the treatment and management of the patient
Aims and objectives: To study the histopathological spectrum of salivary gland neoplasm in patients presenting to a tertiary care center
Materials and methods: The present study was conducted in the Pathology department of Dr.Shankarrao Chavan Government Medical College and Hospital , Nanded , on the surgically resected salivary gland tumor specimens received for routine histopathological evaluation, from January 2020 to January 2021.
Results: In the present study parotid gland was the most commonly affected i.e., in 41(78.85%) patients followed by submandibular gland in 9 (17.31%) patients and 2(3.84%) patients had lesions in minor salivary glands. Among the 43 neoplastic lesions, 31 (72.09%) cases were be nignneoplasms and 12(27.91%) were malignantneoplasms. Pleomorphic Adenoma was the most common salivary gland tumor followed by war thin tumor. Mucoepidermoid carcinoma was reported to be the most common malignant salivary gland tumor
Conclusion: Salivary gland tumors are relatively less common and they exhibit a wide variety of microscopic appearances even within one particular lesion. Accurate diagnosis is essential as salivary gland neoplasm have diverse clinical and prognostic outcomes.
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1. Luukkaa H. Salivary gland cancer in Finland incidence, histological distribution, outcome and prognostic factors. Turku, Finland: University of Turku; 2010.
2. Akhter J, Hirachand S, Lakhey M. Role of FNAC in the diagnosis of salivary gland swellings. Kathmandu Univ Med J. 2008; 6(22):204-08.
3. Gandhi SH, Purohit TM, Purohit MB, Jethwani D, Vidja M. FNAC Diagnosis of Salivary Gland Lesions With Histopathological correlation. NJIRM.2013; 4(3):70-7.
4. Zajicek J, Eneroth CM, Jakobsson P. Aspiration biopsy of salivary gland tumors. VI. Morphologic studies on smears and histologic sections from mucoepidermoid carcinoma. Acta Cytol. 1976; 20(1):35-41. PMID 1063519.
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7. Arey LB. Developmental anatomy. Philadelphia: W B Saunders; 1974.
8. Nepal A, Chettri ST, Joshi RR, Bhattarai M, Ghimire A, Karki S. Primary salivary gland tumors in Eastern Nepal tertiary Care Hospital. J Nepal Health Res Counc. 2010; 8(1):31-4. PMID 21879011.
9. Ali NS, Nawaz A, Rajput S, Ikram M. Parotidectomy: a review of 112 patients treated at a teaching hospital in Pakistan. Asian Pac J Cancer Prev. 2010; 11(4):1111-3. PMID 21133633.
10. Moghadam SA, Moghadam FA, Dad far M. Epithelial salivary gland tumors in Ahvaz, Southwest of Iran. J Dent Res Dent Clin Dent Prospect. 2010; 4:120-23.
11. Dandapat MC, Rath BK, Patnaik BK, Dash SN. Tumors of salivary glands. Indian J Surg. 1991; 53:200.
12. Rewusuwan S, Settakorn J, Mahanupab P. Salivary gland tumors in MaharajNakorn Chiang Mai hospital: A retrospective study of 198 cases. Chiang Mai Bull. 2006; 45(2):45-3.
13. Shrestha S, Pandey G, Pun C, Bhatta R, Shahi R. Histopathological Pattern of Salivary Gland Tumors. J Pathol Nep. 2014; 4(7):520-4. doi: 10.3126/jpn.v4i7.10291.
14. Bashir S, Mustafa F, Malla HA, Khan AH, Rasool M, Sharma S. Histopathological spectrum of salivary gland tumors: A 10 year experience. Sch. J. App. Med Sci. 2013; 1(6):1070-4.
15. Richardson GS, Dickason WL, Gaisford JC, Hanna DC. Tumors of salivary glands. An analysis of 752 cases. Plast Reconstr Surg. 1975; 55(2):131-8. doi: 10.1097/00006534-197502000-00001, PMID 1118472.
16. Vargas PA, Gerhard R, Araújo Filho VJ, de Castro IV. Salivary gland tumors in a Brazilian population: a retrospective study of 124 cases. Rev Hosp Clin Fac Med Sao Paulo. 2002; 57(6):271-6. doi: 10.1590/s0041-87812002000600005. PMID 12612759.
17. K B, Urs A N R, J V, Kotasthane S D, G K HISTOPATHOLOGICAL STUDY OF SALIVARY GLAND TUMOURS. jemds. 2016; 5(72):5240-4. doi: 10.14260/jemds/2016/1187.
18. Ahmad S, Lateef M, Ahmad R. Clinic pathological study of primary salivary gland tumors in Kashmir. JK Pract. 2002; 9(4):231-3.
19. Bashir S, Mustafa F, Malla HA, Khan AH, Rasool M, Sharma S. Histopathological spectrum of salivary gland tumors: A 10 year experience. Sch. J. App. Med Sci. 2013; 1(6):1070-4.
References
2. Akhter J, Hirachand S, Lakhey M. Role of FNAC in the diagnosis of salivary gland swellings. Kathmandu Univ Med J. 2008; 6(22):204-08.
3. Gandhi SH, Purohit TM, Purohit MB, Jethwani D, Vidja M. FNAC Diagnosis of Salivary Gland Lesions With Histopathological correlation. NJIRM.2013; 4(3):70-7.
4. Zajicek J, Eneroth CM, Jakobsson P. Aspiration biopsy of salivary gland tumors. VI. Morphologic studies on smears and histologic sections from mucoepidermoid carcinoma. Acta Cytol. 1976; 20(1):35-41. PMID 1063519.
5. Eveson JW, Cawson RA. Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution. J Pathol. 1985; 146(1):51-8. doi: 10.1002/path.1711460106, PMID 4009321.
6. Spiro RH. Salivary neoplasm: overview of a 35-year experience with 2,807 patients. Head Neck Surg. 1986; 8(3):177-84. doi: 10.1002/hed.2890080309, PMID 3744850.
7. Arey LB. Developmental anatomy. Philadelphia: W B Saunders; 1974.
8. Nepal A, Chettri ST, Joshi RR, Bhattarai M, Ghimire A, Karki S. Primary salivary gland tumors in Eastern Nepal tertiary Care Hospital. J Nepal Health Res Counc. 2010; 8(1):31-4. PMID 21879011.
9. Ali NS, Nawaz A, Rajput S, Ikram M. Parotidectomy: a review of 112 patients treated at a teaching hospital in Pakistan. Asian Pac J Cancer Prev. 2010; 11(4):1111-3. PMID 21133633.
10. Moghadam SA, Moghadam FA, Dad far M. Epithelial salivary gland tumors in Ahvaz, Southwest of Iran. J Dent Res Dent Clin Dent Prospect. 2010; 4:120-23.
11. Dandapat MC, Rath BK, Patnaik BK, Dash SN. Tumors of salivary glands. Indian J Surg. 1991; 53:200.
12. Rewusuwan S, Settakorn J, Mahanupab P. Salivary gland tumors in MaharajNakorn Chiang Mai hospital: A retrospective study of 198 cases. Chiang Mai Bull. 2006; 45(2):45-3.
13. Shrestha S, Pandey G, Pun C, Bhatta R, Shahi R. Histopathological Pattern of Salivary Gland Tumors. J Pathol Nep. 2014; 4(7):520-4. doi: 10.3126/jpn.v4i7.10291.
14. Bashir S, Mustafa F, Malla HA, Khan AH, Rasool M, Sharma S. Histopathological spectrum of salivary gland tumors: A 10 year experience. Sch. J. App. Med Sci. 2013; 1(6):1070-4.
15. Richardson GS, Dickason WL, Gaisford JC, Hanna DC. Tumors of salivary glands. An analysis of 752 cases. Plast Reconstr Surg. 1975; 55(2):131-8. doi: 10.1097/00006534-197502000-00001, PMID 1118472.
16. Vargas PA, Gerhard R, Araújo Filho VJ, de Castro IV. Salivary gland tumors in a Brazilian population: a retrospective study of 124 cases. Rev Hosp Clin Fac Med Sao Paulo. 2002; 57(6):271-6. doi: 10.1590/s0041-87812002000600005. PMID 12612759.
17. K B, Urs A N R, J V, Kotasthane S D, G K HISTOPATHOLOGICAL STUDY OF SALIVARY GLAND TUMOURS. jemds. 2016; 5(72):5240-4. doi: 10.14260/jemds/2016/1187.
18. Ahmad S, Lateef M, Ahmad R. Clinic pathological study of primary salivary gland tumors in Kashmir. JK Pract. 2002; 9(4):231-3.
19. Bashir S, Mustafa F, Malla HA, Khan AH, Rasool M, Sharma S. Histopathological spectrum of salivary gland tumors: A 10 year experience. Sch. J. App. Med Sci. 2013; 1(6):1070-4.