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Kikuchi's disease: a case report from west india
Corresponding Author(s) : dhukiya Ramniwas
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 2 No. 4 (2014): 2014 Volume 2- Issue -4
Abstract
Kikuchi-Fujimoto disease (KFD), or histiocytic necrotizing lymphadenitis, is a rare benign, self-limiting cervical lymphadenitis of unknown etiology. It closely mimic infective and immunological disorders. CASE REPORT- we report a 20-year-old male of west presented with multiple neck swellings and fever of 15 days duration. Clinical Examination revealed unilateral large, mobile and tender-cervical lymphadenopathy. Lymph nodes were not palpable in other parts of the body. Examination of other systems was normal. Routine hematological parameters were within normal limits. ESR was 90mm/1st hr. Fine needle aspiration cytology (FNAC) of the right supraclavicular cervical node showed features suggestive of reactive lymphadenitis. After that, lymph node biopsy was done and the histological features suggested the diagnosis of Kikuchi-Fujimoto disease. The Patient was treated symptomatically with nonsteroidal anti-inflammatory drugs and the lymph nodes regressed in four weeks. Conclusion- Although the incidence of Kikuchi-Fujimoto disease is rare, Kikuchi Fujimoto disease is considered a disorder with a self-limited course and af avorable outcome.
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[1] Dorfman RF. Histiocytic necrotizing lymphadenitis of Kikuchi and Fujimoto [editorial]. Arch Pathol Lab Med.
1987;111:1026-1029.
[2] Kuo T. Kikuchi's disease (histiocytic necrotizing lymphadenitis): a clinicopathologic study of 79 cases with an analysis of histologic subtypes, immunohistology and DNA ploidy. Am J Surg Pathol 1995;19:798–809.
[3] Sousa Ade A, Soares JM, de Sa Santos MH, Martins MP, Salles JM. Kikuchi-Fujimoto disease: three case reports. Sao Paulo Med J. 2010;128(4):232-235.
[4] Lin HC, Su CY, Huang CC, Hwang CF, Chien CY: Kikuchi's disease. A review and analysis of 61 cases. Otoralyngol Head Neck Surg 2003, 128:650-653
[5] Tsang WYW, Chan JKC, Ng CS: Kikuchi's lymphadenitis. A morphologic analysis of 75 cases with special reference to unusual features. Am J Surg Pathol 1994, 18:219-231.
[6] Bosch X, Guilabert A, Miquel R, Campo E: Enigmatic Kikuchi-Fujimoto disease: a comprehensive review. Am J Clin Pathol 2004, 122:141-152
[7] Louis N, Hanley M, Davidson NM. Kikuchi– Fujimoto disease: a report of two cases and an
overview. The Journal of Laryngology Otology 1994;108:1001-1004. doi:10.1017/ S0022215100128749
[8] Pileri AS, Pileri A, Yasukawa K, Kuo TS, Sullivan K: The Karma of Kiluchi's disease. Clin Immunol 2005, 114:27-29.
[9] Dorfman RF: Histiocytic necrotizing lymphadenitis of Kikuchi and Fujimoto. Arch Pathol Lab Med 1987, 111:1026-1029.
References
1987;111:1026-1029.
[2] Kuo T. Kikuchi's disease (histiocytic necrotizing lymphadenitis): a clinicopathologic study of 79 cases with an analysis of histologic subtypes, immunohistology and DNA ploidy. Am J Surg Pathol 1995;19:798–809.
[3] Sousa Ade A, Soares JM, de Sa Santos MH, Martins MP, Salles JM. Kikuchi-Fujimoto disease: three case reports. Sao Paulo Med J. 2010;128(4):232-235.
[4] Lin HC, Su CY, Huang CC, Hwang CF, Chien CY: Kikuchi's disease. A review and analysis of 61 cases. Otoralyngol Head Neck Surg 2003, 128:650-653
[5] Tsang WYW, Chan JKC, Ng CS: Kikuchi's lymphadenitis. A morphologic analysis of 75 cases with special reference to unusual features. Am J Surg Pathol 1994, 18:219-231.
[6] Bosch X, Guilabert A, Miquel R, Campo E: Enigmatic Kikuchi-Fujimoto disease: a comprehensive review. Am J Clin Pathol 2004, 122:141-152
[7] Louis N, Hanley M, Davidson NM. Kikuchi– Fujimoto disease: a report of two cases and an
overview. The Journal of Laryngology Otology 1994;108:1001-1004. doi:10.1017/ S0022215100128749
[8] Pileri AS, Pileri A, Yasukawa K, Kuo TS, Sullivan K: The Karma of Kiluchi's disease. Clin Immunol 2005, 114:27-29.
[9] Dorfman RF: Histiocytic necrotizing lymphadenitis of Kikuchi and Fujimoto. Arch Pathol Lab Med 1987, 111:1026-1029.