Association between ABO blood group and Helicobacter pylori infection study in South India

Abstract

Introduction
There is no consensus among the existing literature on the relationship between ABO blood groups and risk of Helicobacter pylori infection. However, histo-blood group carbohydrates are proposed to influence the risk of acquiring this pathogen via effects on adhesion to the gastric mucosa. The objective of this study was to evaluate the association between ABO blood groups and H. pylori infection.
Aim and Objective
To study the incidence and prevalence of H.Pylori infections among the various blood groups.
Materials and Methods
? Study area- Thandalam
? Study period-January 2019- March 2019
? Study design-Prospective study
? Study population- Patients reporting for endoscopy with dyspepsia and other upper GI symptoms
? Sample size- 120 patients
? Sampling method- Simple random Sampling
? Data analysis- Descriptive statistics will be calculated for the variables using SPSS.
Result
In this study, 120 patients reporting to endoscopy division of gastroenterology department of Saveetha Medical College and Hospital were included. 55.8% of the participants were male and 44.2% of the participants were female. The general prevalence of Helicobacter pylori infection in the participants is 57.5%. The prevalence of H.pylori in A blood group is 26.7%, in B blood group is 21.7%, in AB blood group is 7.5%, O blood group is 44.2%. H pylori infections occur more in people with the O blood group ( p<0.004).                                                    Conclusion
We observe a higher prevalence of H. Pylori infection in patients with O blood group. There are several studies, investigation which point towards this relation and establish a relationship between O blood group and H. Pylori infection.