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A Comparative Clinical Study to Evaluate the Efficacy of Tiladi Lepam and Its Gel Form in the Management of Dushta Vrana
Corresponding Author(s) : Manoj Kumar
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 13 No. 2 (2025): 2025 Volume -13 - Issue 2
Abstract
Dushta Vrana (chronic or infected wound) is a frequently encountered condition in surgical practice and can significantly compromise a patient's health due to complications like slough, infection, and foreign bodies, all of which interfere with the natural wound healing process. A clean, uncontaminated wound in a healthy body heals more efficiently with minimal scarring, whereas a contaminated wound requires proper management to initiate healing. The primary therapeutic goal in the treatment of Dushta Vrana is to convert it into a Shuddha Vrana, thereby facilitating the process of Ropana (wound healing).
This clinical study was undertaken to evaluate the efficacy of Tiladi Lepa and its gel-based formulation in managing Dushta Vrana. A total of 40 clinically diagnosed patients were randomly divided into two groups of 20 patients each. Group A received local application of Tiladi Lepa, while Group B was treated with the gel form of Tiladi Lepa.
The evaluation was carried out using both subjective parameters (pain, burning sensation, itching) and objective parameters (wound size, discharge, odor, and granulation tissue formation). Both groups showed statistically significant improvement (P < 0.05); however, the Gel form of Tiladi Lepa (Group B) demonstrated relatively better outcomes in most clinical parameters.
Although the statistical difference between the two groups was not highly significant, the comparative analysis of individual parameters and the overall response suggests that the gel formulation of Tiladi Lepa offers superior Ropana (healing) properties compared to the traditional Tiladi Lepa. Thus, the gel form may be considered more effective in promoting wound healing in cases of Dushta Vrana.
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- Sushruta. Sushruta Samhita, Chikitsasthana, Chapter 1, Shlokas 1–2. Translated by Shastri AD. Varanasi: Chaukhambha Sanskrit Sansthan; 2007. p. 1.
- Sushruta. Sushruta Samhita, Chikitsasthana, Chapter 2, Shlokas 8–9. Translated by Shastri AD. Varanasi: Chaukhambha Sanskrit Sansthan; 2007. p. 14.
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- Sushruta. Sushruta Samhita, Chikitsasthana, Chapter 23, Shloka 3. Translated by Shastri AD. Varanasi: Chaukhambha Sanskrit Sansthan; 2007. p. 97.
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- chakradutta,by bajpayee pandit and jagarnath Sharma, bhagandar chitsa adhikara shloka 10 pg 206.
- https://www.academia.edu/34373024/Preparation_of_tiladi_lepam_in_gel_form.
- Sushruta. Sushruta Samhita, Sutrasthana, Chapter 21, Shloka 40. Translated by Shastri AD. Varanasi: Chaukhambha Sanskrit Sansthan; 2007. p. 94.
- Charaka. Charaka Samhita, Chikitsasthana, Chapter 25, Shlokas 10–16. Edited by Pandey K, Chaturvedi G. Varanasi: Chaukhambha Bharati Academy; 2007. p. 698–699.
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- Vagbhata. Ashtanga Hridaya, Uttar Tantra, Chapter 25, Shlokas 3–4. Edited by Gupta A. Varanasi: Chaukhambha Prakashan; 2008. p. 735.
- Charaka. Charaka Samhita, Chikitsasthana, Chapter 25, Shloka 86. Edited by Pandey K, Chaturvedi G. Varanasi: Chaukhambha Bharati Academy; 2007. p. 710.
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Sushruta. Sushruta Samhita, Chikitsasthana, Chapter 23, Shloka 3. Translated by Shastri AD. Varanasi: Chaukhambha Sanskrit Sansthan; 2007. p. 97.
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Sushruta. Sushruta Samhita, Chikitsasthana, Chapter 1, Shloka 8. Translated by Shastri AD. Varanasi: Chaukhambha Sanskrit Sansthan; 2007. p. 4.
chakradutta,by bajpayee pandit and jagarnath Sharma, bhagandar chitsa adhikara shloka 10 pg 206.
https://www.academia.edu/34373024/Preparation_of_tiladi_lepam_in_gel_form.
Sushruta. Sushruta Samhita, Sutrasthana, Chapter 21, Shloka 40. Translated by Shastri AD. Varanasi: Chaukhambha Sanskrit Sansthan; 2007. p. 94.
Charaka. Charaka Samhita, Chikitsasthana, Chapter 25, Shlokas 10–16. Edited by Pandey K, Chaturvedi G. Varanasi: Chaukhambha Bharati Academy; 2007. p. 698–699.
Vagbhata. Ashtanga Hridaya, Uttar Tantra, Chapter 25, Shlokas 1, 5–10. Edited by Gupta A. Varanasi: Chaukhambha Prakashan; 2008. p. 735–736.
Sushruta. Sushruta Samhita, Chikitsasthana, Chapter 2, Shlokas 8–9. Translated by Shastri AD. Varanasi: Chaukhambha Sanskrit Sansthan; 2007. p. 14.
Vagbhata. Ashtanga Hridaya, Uttar Tantra, Chapter 25, Shlokas 3–4. Edited by Gupta A. Varanasi: Chaukhambha Prakashan; 2008. p. 735.
Charaka. Charaka Samhita, Chikitsasthana, Chapter 25, Shloka 86. Edited by Pandey K, Chaturvedi G. Varanasi: Chaukhambha Bharati Academy; 2007. p. 710.
Taber CW. Taber’s Cyclopedic Medical Dictionary. 17th ed. New Delhi: Jaypee Brothers Medical Publishers; 2009. p. 2165.
Dorland. Dorland’s Pocket Medical Dictionary. 25th ed. New Delhi: Oxford & IBH Publishing; 2007. p. 844.
Taber CW. Taber’s Cyclopedic Medical Dictionary. 17th ed. New Delhi: Jaypee Brothers Medical Publishers; 2009. p. 2067.
Government of India. The Ayurvedic Pharmacopoeia of India. Vol. 1, Part 2. New Delhi: Ministry of Health and Family Welfare, Department of AYUSH; 2007. p. 73.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11121385/?utm_source=chatgpt.com