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Vol. 13 No. 2 (2025): 2025 Volume -13 - Issue 2

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Submitted
April 9, 2025
Published
April 9, 2025
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Enantiomeric separation of drugs by HPLC

Mahroof Ahmed
Student B.Pharmacy, Mewar University, Chittorgarh, Rajasthan, India
Kulbir Singh
Student B.Pharmacy, Mewar University, Chittorgarh, Rajasthan, India
Shubam Singh
Student, Deen Dayal Rustogi College of Pharmacy, Haileymandi, Haryana, India
Tanya Sharma4
Assistant Professor, Mewar University, Chittorgarh, Rajasthan, India

International Journal of Allied Medical Sciences and Clinical Research, Vol. 13 No. 2 (2025): 2025 Volume -13 - Issue 2

Abstract

The need to separate drug enantiomers isn't just a technical challenge it s a crucial aspect of making medicines safer and more effective. High-Performance Liquid Chromatography (HPLC) has proven itself as a reliable tool for achieving precise and reproducible enantiomeric separations. This review explores various strategies for enantiomeric separation via HPLC, from the use of chiral stationary phases to clever tweaks in the mobile phase. We ll also dive into real-world applications, the hurdles researchers face, and how the field is evolving.

Keywords

Enantiomeric separation, CSPs, HPLC, Chirality in pharmaceuticals, Drug purity.
1.
Mahroof Ahmed, Kulbir Singh, Shubam Singh, Tanya Sharma4. Enantiomeric separation of drugs by HPLC. Int. J. of Allied Med. Sci. and Clin. Res. [Internet]. 2025 Apr. 9 [cited 2025 Apr. 24];13(2):149-51. Available from: https://ijamscr.com/ijamscr/article/view/1598
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