Primary osteosarcoma of the breast- a case report
Corresponding Author(s) : Dr.Ramniwas dhukiya
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 2 No. 4 (2014): 2014 Volume 2- Issue -4
Abstract
Primary extra-osseous osteogenic sarcomas in the breast is extremely rare. It can arise as a result of osseous Primary extra-osseous osteogenic sarcomas have been reported in many tissues of the body metaplasia in a pre-existing benign or malignant neoplasm of the breast or as non-phylloides sarcoma from the soft tissue of a previously normal breast. Case presentation: A 45 year-old north indian woman was clinically diagnosed to have carcinoma of the right breast. The histology report of excisional biopsy of the mass showed a malignant neoplasm comprising islands of chondroblastic and osteoblastic stromal cells. This report changed the diagnosis from carcinoma to osteogenic sarcoma of the breast. Sections from the lumpectomy specimen confirmed the diagnosis of osteogenic sarcoma. She lost in follow-up. Conclusion: A diagnosis of osteogenic sarcoma of the breast was made based on histology report and after excluding an osteogenic sarcoma arising from underlying ribs and sternum.
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[1] I. A. Voutsadakis, K. Zaman, and S. Leyvraz, “Breast sarcomas: current and future perspectives,” Breast, vol. 20, no. 3, pp. 199–204, 2011.
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[6] Silver SA, Tavassoli FA: Osteosarcomatous differentiation in phyllodes tumors. Am J Surg Pathol 1999, 23:815-821.
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[8] Chung EB, Enzinger FM . Extraskeletal osteosarcoma. Cancer 1987 ; 60 : 1132 – 42 .
[9] Bahrami A, R essetkova E, Ro J, e t al. P rimary osteosarcoma of the breast:report of 2 cases . Arch Pathol Lab Med 2007 ; 131:792–5.
[10] Momoi H, Wada Y, Sarumaru S, Tamaki N, Gomi T, Kanaya S, Katayama T, Ootoshi M, Fukumoto M: Primary osteosarcoma of the breast. Breast Cancer 2004,11:396-400.
[11] T. O. Ogundiran, S. A. Ademola, O.M. Oluwatosin,E.E.Akang, and C. A. Adebamowo, “Primary osteogenic sarcoma of thebreast,” World Journal of Surgical Oncology, vol. 4, pp. 90–93, 2006.
[12] S. Khan, E. A. Griffiths, N. Shah, and S. Ravi, “Primary osteogenic sarcoma of the breast: a case report,” Cases Journal, vol. 1, pp. 148–151, 2008.
[13] B. J. Barrow,N.A. Janjan, H. Gutman et al., “Role of radiotherapy in sarcoma of the breast—a retrospective review of theM.D. Anderson experience,” Radiotherapy and Oncology, vol. 52, no. 2, pp. 173–178, 1999.
References
[2] Y. M. Kirova, J. R. Vilcoq, B. Asselain, X. Sastre-Garau, and A. Fourquet, “Radiation-induced sarcomas after radiotherapy for breast carcinoma: a large-scale single-institution review,” Cancer, vol. 104, no. 4, pp. 856–863, 2005.
[3] G. Vorobiof, G. Hariparsad, W. Freinkel, H. Said, and D. A. Vorobiof, “Primary osteosarcoma of the breast: a case report,”Breast Journal, vol. 9, no. 3, pp. 231–233, 2003.
[4] Remadi S, Doussis-Anagnostopoulu I, MacGee W: Primary osteosarcoma of the breast. Pathol Res Pract 1995, 191:471-474.
[5] Suzuki T, Kikuchi K, Horiguchi Y, Nihei K, Asano S: Breast carcinoma with features of osteosarcoma-a light and electron microscopic and immunohistochemical study. Jap J Cancer Clin1989, 35:1453-1460.
[6] Silver SA, Tavassoli FA: Osteosarcomatous differentiation in phyllodes tumors. Am J Surg Pathol 1999, 23:815-821.
[7] Arraztoa J, Oddo D, San Martin S, Arraztoa JA, Becker P, Valuenzela J: Unusual sarcomas of the breast. Report of 3 cases. RevistaMedica de Chile 1989, 117:435-439.
[8] Chung EB, Enzinger FM . Extraskeletal osteosarcoma. Cancer 1987 ; 60 : 1132 – 42 .
[9] Bahrami A, R essetkova E, Ro J, e t al. P rimary osteosarcoma of the breast:report of 2 cases . Arch Pathol Lab Med 2007 ; 131:792–5.
[10] Momoi H, Wada Y, Sarumaru S, Tamaki N, Gomi T, Kanaya S, Katayama T, Ootoshi M, Fukumoto M: Primary osteosarcoma of the breast. Breast Cancer 2004,11:396-400.
[11] T. O. Ogundiran, S. A. Ademola, O.M. Oluwatosin,E.E.Akang, and C. A. Adebamowo, “Primary osteogenic sarcoma of thebreast,” World Journal of Surgical Oncology, vol. 4, pp. 90–93, 2006.
[12] S. Khan, E. A. Griffiths, N. Shah, and S. Ravi, “Primary osteogenic sarcoma of the breast: a case report,” Cases Journal, vol. 1, pp. 148–151, 2008.
[13] B. J. Barrow,N.A. Janjan, H. Gutman et al., “Role of radiotherapy in sarcoma of the breast—a retrospective review of theM.D. Anderson experience,” Radiotherapy and Oncology, vol. 52, no. 2, pp. 173–178, 1999.