Probiotics and Blood Presure: a Literature Review
Corresponding Author(s) : Enny Trisanti
ennytrisanti@gmail.com
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 8 No. 2 (2020): 2020 Volume 8- Issue -2
Abstract
Background
Hypertension is a noncommunicable disease that can effect many complication for health, therefore we need effective blood pressure management. Effective management can be combined and non-pharmacological therapy through probiotics.
Objectives
The aims of this paper was to analyze the effectiveness of probiotics to reduce blood pressure.
Research methods
Literature review was based on the search of Google Scholar, Science Direct and Pubmed published from 2010 to 2019. The keywords used are probiotics, blood pressure, probiotics for blood pressure, and hypertension. Articles used using inclusion and exclusion criteria.
Result
The literature review in accordance with the search strategy in getting as many as 285 articles published ten years related to the effect of probiotic on blood pressure. 95 were deleted because it has the same title. A total of 162 articles are not relevant to the article, after using the inclusion and exclusion criteria obtained 8 articles that are eligible for this literature review. As results, probiotics can be used to reduce blood pressure consuming a variety of species and over 6 weeks in duration. It can inhibit the Angiotensin Converting Enzyme (ACE), and reduce the production of angiotensin-I to angiotensin-II.
Conclusion
Probiotics therapy can be used for reduce blood pressure
Keywords
Probiotic
Blood pressure
Probiotic for blood pressure
Hypertension
1.
Enny Trisanti. Probiotics and Blood Presure: a Literature Review. Int. J. of Allied Med. Sci. and Clin. Res. [Internet]. 2020 Aug. 15 [cited 2026 Apr. 16];8(2):287-93. Available from: https://ijamscr.com/ijamscr/article/view/864
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References
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[1]. M. Sarki, C. U. Nduka, S. Stranges, N. B. Kandala, and O. A. Uthman, “Prevalence of Hypertension in Low- and A Systematic Review and Meta-Analysis,” Medicine (Baltimore), 94(50), 2015, 1–16.
[2]. Kemenkes Badan Penelitian dan Pengembangan Kesehatan, Hasil Utama RISKESDAS 2018. Jakarta: Kemenkes, 2018.
[3]. J. E. Hall et al., “Hypertension: Physiology and pathophysiology,” Compr. Physiol., 2(4), 2012, 2393–2442.
[4]. T. Krause and K. Lovibond, “Management of hypertension : summary of NICE,” BMJ, 2011, 1– 6.
[5]. S. Stranges and F. P. Cappuccio, “Nonpharmacologic Management of Hypertension,” Compr. Hypertens., 2007, 1129–1146,.
[6]. M. Hajifaraji, F. Jahanjou, F. Abbasalizadeh, N. Aghamohammadzadeh, M. M. Abbasi, and N. Dolatkhah, “Effect of probiotic supplementation on blood pressure of females with gestational diabetes mellitus: A randomized double blind controlled clinical trial,” Iran. Red Crescent Med. J., 19(6), 2017.
[7]. M. Hariri, R. Salehi, A. Feizi, M. Mirlohi, R. Ghiasvand, and N. Habibi, “The Effect Probiotic Soy Milk and Soy Milk on Anthropometri Measures and Blood Pressure in Patients with Type II Diabetes Mellitus: A Randomized Double-Blind Clinical Trial,” Genes Nutr., 10(6), 2014, 1–8.
[8]. J. Chang et al., “Effect of Functional Yogurt NY-YP901 in Improving the Trait of Metabolic Syndrome,” Eur. J. Clin. Nutr., 65(11), 2011, 1250–1255.
[9]. M. L. Jones, C. J. Martoni, S. Tamber, M. Parent, and S. Prakash, “Evaluation of Safety and Tolerance of Microencapsulated Lactobacillus Reuteri NCIMB 30242 in a Yogurt Formulation : A Randomized, Placebo-Controlled , Double-Blind Study,” Food Chem. Toxicol., 50(6), 2012, 2216–2223.
[10]. H. Chen, Z. Ji, G. Shu, and H. Xing, “Effect of Probiotic Lactobacillus Strains on Angiotensin I Converting Enzyme Inhibitory Activity from Fermented Goat Milk,” Adv. Mater. Res., 531, 2012, 442–445.
[11]. K. K. Sharafedtinov et al., “Hypocaloric Diet Supplemented with Probiotic Cheese Improves Body Mass Index and Blood Pressure Indices of Obese Hypertensive Patients - A Randomized Double-Blind Placebo-Controlled Pilot Study,” Nutr. J., 12(1), 2013, 1– 11.
[12]. K. L. Ivey, J. M. Hodgson, D. A. Kerr, P. L. Thompson, B. Stojceski, and R. L. Prince, “The Effect of Yoghurt and Its Probiotics on Blood Pressure and Serum Lipid Profile; A Randomised Controlled Trial,” Nutr. Metab. Cardiovasc. Dis., 25(1), 2015, 46–51.
[13]. M. L. Jones, C. J. Martoni, E. Di, R. R. Simon, and S. Prakash, “Evaluation of Clinical Safety and Tolerance of a Lactobacillus Reuteri NCIMB 30242 Supplement Capsule : A Randomized Control Trial,” Regul. Toxicol. Pharmacol, 63(2), 2012, 313–320.
[14]. P. Savard, B. Lamarche, M. E. Paradis, H. Thiboutot, É. Laurin, and D. Roy, “Impact of Bifidobacterium Animalis Subsp. Lactis BB-12 and, Lactobacillus Acidophilus LA-5- Containing Yoghurt, on Fecal Bacterial Counts of Healthy Adults,” Int. J. Food Microbiol., 149(1), 2011, 50–57.
[15]. Tim Biosyafa Publishing, Probiotic Multi-Use Solution Cycle from Home. Surabaya: Biosyafa Publishing, 2019.
A. Upadrasta and R. S. Madempudi, “Probiotics and blood pressure: Current insights,” Integr. Blood Press. Control, 9, 2016, 33–42.
[16]. Hernawati, “The Renin-Angiotensin-Aldosterone System: Its Role in Regulating Blood Pressure and Hypertension,” J. Chem. Inf. Model., 53(9), 2013, 1689–1699.
References
[1]. M. Sarki, C. U. Nduka, S. Stranges, N. B. Kandala, and O. A. Uthman, “Prevalence of Hypertension in Low- and A Systematic Review and Meta-Analysis,” Medicine (Baltimore), 94(50), 2015, 1–16.
[2]. Kemenkes Badan Penelitian dan Pengembangan Kesehatan, Hasil Utama RISKESDAS 2018. Jakarta: Kemenkes, 2018.
[3]. J. E. Hall et al., “Hypertension: Physiology and pathophysiology,” Compr. Physiol., 2(4), 2012, 2393–2442.
[4]. T. Krause and K. Lovibond, “Management of hypertension : summary of NICE,” BMJ, 2011, 1– 6.
[5]. S. Stranges and F. P. Cappuccio, “Nonpharmacologic Management of Hypertension,” Compr. Hypertens., 2007, 1129–1146,.
[6]. M. Hajifaraji, F. Jahanjou, F. Abbasalizadeh, N. Aghamohammadzadeh, M. M. Abbasi, and N. Dolatkhah, “Effect of probiotic supplementation on blood pressure of females with gestational diabetes mellitus: A randomized double blind controlled clinical trial,” Iran. Red Crescent Med. J., 19(6), 2017.
[7]. M. Hariri, R. Salehi, A. Feizi, M. Mirlohi, R. Ghiasvand, and N. Habibi, “The Effect Probiotic Soy Milk and Soy Milk on Anthropometri Measures and Blood Pressure in Patients with Type II Diabetes Mellitus: A Randomized Double-Blind Clinical Trial,” Genes Nutr., 10(6), 2014, 1–8.
[8]. J. Chang et al., “Effect of Functional Yogurt NY-YP901 in Improving the Trait of Metabolic Syndrome,” Eur. J. Clin. Nutr., 65(11), 2011, 1250–1255.
[9]. M. L. Jones, C. J. Martoni, S. Tamber, M. Parent, and S. Prakash, “Evaluation of Safety and Tolerance of Microencapsulated Lactobacillus Reuteri NCIMB 30242 in a Yogurt Formulation : A Randomized, Placebo-Controlled , Double-Blind Study,” Food Chem. Toxicol., 50(6), 2012, 2216–2223.
[10]. H. Chen, Z. Ji, G. Shu, and H. Xing, “Effect of Probiotic Lactobacillus Strains on Angiotensin I Converting Enzyme Inhibitory Activity from Fermented Goat Milk,” Adv. Mater. Res., 531, 2012, 442–445.
[11]. K. K. Sharafedtinov et al., “Hypocaloric Diet Supplemented with Probiotic Cheese Improves Body Mass Index and Blood Pressure Indices of Obese Hypertensive Patients - A Randomized Double-Blind Placebo-Controlled Pilot Study,” Nutr. J., 12(1), 2013, 1– 11.
[12]. K. L. Ivey, J. M. Hodgson, D. A. Kerr, P. L. Thompson, B. Stojceski, and R. L. Prince, “The Effect of Yoghurt and Its Probiotics on Blood Pressure and Serum Lipid Profile; A Randomised Controlled Trial,” Nutr. Metab. Cardiovasc. Dis., 25(1), 2015, 46–51.
[13]. M. L. Jones, C. J. Martoni, E. Di, R. R. Simon, and S. Prakash, “Evaluation of Clinical Safety and Tolerance of a Lactobacillus Reuteri NCIMB 30242 Supplement Capsule : A Randomized Control Trial,” Regul. Toxicol. Pharmacol, 63(2), 2012, 313–320.
[14]. P. Savard, B. Lamarche, M. E. Paradis, H. Thiboutot, É. Laurin, and D. Roy, “Impact of Bifidobacterium Animalis Subsp. Lactis BB-12 and, Lactobacillus Acidophilus LA-5- Containing Yoghurt, on Fecal Bacterial Counts of Healthy Adults,” Int. J. Food Microbiol., 149(1), 2011, 50–57.
[15]. Tim Biosyafa Publishing, Probiotic Multi-Use Solution Cycle from Home. Surabaya: Biosyafa Publishing, 2019.
A. Upadrasta and R. S. Madempudi, “Probiotics and blood pressure: Current insights,” Integr. Blood Press. Control, 9, 2016, 33–42.
[16]. Hernawati, “The Renin-Angiotensin-Aldosterone System: Its Role in Regulating Blood Pressure and Hypertension,” J. Chem. Inf. Model., 53(9), 2013, 1689–1699.
[2]. Kemenkes Badan Penelitian dan Pengembangan Kesehatan, Hasil Utama RISKESDAS 2018. Jakarta: Kemenkes, 2018.
[3]. J. E. Hall et al., “Hypertension: Physiology and pathophysiology,” Compr. Physiol., 2(4), 2012, 2393–2442.
[4]. T. Krause and K. Lovibond, “Management of hypertension : summary of NICE,” BMJ, 2011, 1– 6.
[5]. S. Stranges and F. P. Cappuccio, “Nonpharmacologic Management of Hypertension,” Compr. Hypertens., 2007, 1129–1146,.
[6]. M. Hajifaraji, F. Jahanjou, F. Abbasalizadeh, N. Aghamohammadzadeh, M. M. Abbasi, and N. Dolatkhah, “Effect of probiotic supplementation on blood pressure of females with gestational diabetes mellitus: A randomized double blind controlled clinical trial,” Iran. Red Crescent Med. J., 19(6), 2017.
[7]. M. Hariri, R. Salehi, A. Feizi, M. Mirlohi, R. Ghiasvand, and N. Habibi, “The Effect Probiotic Soy Milk and Soy Milk on Anthropometri Measures and Blood Pressure in Patients with Type II Diabetes Mellitus: A Randomized Double-Blind Clinical Trial,” Genes Nutr., 10(6), 2014, 1–8.
[8]. J. Chang et al., “Effect of Functional Yogurt NY-YP901 in Improving the Trait of Metabolic Syndrome,” Eur. J. Clin. Nutr., 65(11), 2011, 1250–1255.
[9]. M. L. Jones, C. J. Martoni, S. Tamber, M. Parent, and S. Prakash, “Evaluation of Safety and Tolerance of Microencapsulated Lactobacillus Reuteri NCIMB 30242 in a Yogurt Formulation : A Randomized, Placebo-Controlled , Double-Blind Study,” Food Chem. Toxicol., 50(6), 2012, 2216–2223.
[10]. H. Chen, Z. Ji, G. Shu, and H. Xing, “Effect of Probiotic Lactobacillus Strains on Angiotensin I Converting Enzyme Inhibitory Activity from Fermented Goat Milk,” Adv. Mater. Res., 531, 2012, 442–445.
[11]. K. K. Sharafedtinov et al., “Hypocaloric Diet Supplemented with Probiotic Cheese Improves Body Mass Index and Blood Pressure Indices of Obese Hypertensive Patients - A Randomized Double-Blind Placebo-Controlled Pilot Study,” Nutr. J., 12(1), 2013, 1– 11.
[12]. K. L. Ivey, J. M. Hodgson, D. A. Kerr, P. L. Thompson, B. Stojceski, and R. L. Prince, “The Effect of Yoghurt and Its Probiotics on Blood Pressure and Serum Lipid Profile; A Randomised Controlled Trial,” Nutr. Metab. Cardiovasc. Dis., 25(1), 2015, 46–51.
[13]. M. L. Jones, C. J. Martoni, E. Di, R. R. Simon, and S. Prakash, “Evaluation of Clinical Safety and Tolerance of a Lactobacillus Reuteri NCIMB 30242 Supplement Capsule : A Randomized Control Trial,” Regul. Toxicol. Pharmacol, 63(2), 2012, 313–320.
[14]. P. Savard, B. Lamarche, M. E. Paradis, H. Thiboutot, É. Laurin, and D. Roy, “Impact of Bifidobacterium Animalis Subsp. Lactis BB-12 and, Lactobacillus Acidophilus LA-5- Containing Yoghurt, on Fecal Bacterial Counts of Healthy Adults,” Int. J. Food Microbiol., 149(1), 2011, 50–57.
[15]. Tim Biosyafa Publishing, Probiotic Multi-Use Solution Cycle from Home. Surabaya: Biosyafa Publishing, 2019.
A. Upadrasta and R. S. Madempudi, “Probiotics and blood pressure: Current insights,” Integr. Blood Press. Control, 9, 2016, 33–42.
[16]. Hernawati, “The Renin-Angiotensin-Aldosterone System: Its Role in Regulating Blood Pressure and Hypertension,” J. Chem. Inf. Model., 53(9), 2013, 1689–1699.