Review on mouth dissolving tablet of atorvastatin calcium using natural superdisintegrants

Abstract

Oral route is the most preferred for administration of various drugs because it regards as safety, convenient and economic route. Fast dissolving tablets (FDT) are most accepted and exploited for the drug delivery for the patients who are having difficulty with swallowing i.e. mainly paediatrics and geriatric. Atorvastatin calcium is an anti-hyperlipidemic drug that reduces the level of bad cholesterol. Atorvastatin is used to treat high cholesterol and to lower the risk of stroke, heart attack and other heart complication in people with type 2 diabetes, coronary heart disease. In this formulation super disintegrates such as sodium starch glycolate, crosspovidone, Palnatago ovata and guar gum at various concentration used for the preparation of tablets.