A study on phytochemical & anti-nociceptive activity of lonicera ligustrina leaf extract

Abstract

In this study we aimed to elucidate over pharmacological activities of Lonicera-ligustrina (Caprifoliaceae).The ethanolic extract of L. ligustrina (LL) dose dependently had shown analgesic activity. The anti-nociceptive activity of LL was assessed using the Tail-flick model & Tail-immersion model in swiss albino mice. EELL showed the presence of Flavonoids, Terpenoids, Steroids, Alkaloids, Glycosides etc& showed significant analgesic effect with significant increase in reaction time against thermal stimuli & it attributed through decrease in pain due to biogenic amines BK,5 HT, PG’s, NA, NGF, Neuropeptides (SP,CGRP, Interferons&Enkephalins).