Measurement of Malondialdehyde (MDA) as a good Indicator of Lipid Peroxidation

Abstract

Redox homeostasis distruptions play a role in pathological conditions. Many compounds such as hydrogen peroxide are mediators and stimulate oxidative stress. Lipids as the main component of the cellular membrane play a role in maintaining cell structure integrity. The main target lipids of ROS attacks such as oxygen free radicals and lipid oxidation are associated with various pathological conditions. Malondialdehyde (MDA) is the result of lipid peroxidation, which is produced from damage to polyunsaturated fatty acids. MDA is a good indicator of lipid peroxidation