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  3. Vol. 2 No. 1 (2014): 2014 Volume 2- Issue -1
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Vol. 2 No. 1 (2014): 2014 Volume 2- Issue -1

Copyright (c) 2020 Mukesh Sharma

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

A Study on Current Marketed Formulation of Unani Medicine Used in the Treatment of “Zayabetus”

https://doi.org/10.61096/ijamscr.v2.iss1.2014.51-63
Mukesh Sharma
Assistant Professor (Pharmacognosy),Rungta College of Pharmaceutical Sciences and Research,Kohka-Kurud Road Bhilai, Chhattisgarh, India

Corresponding Author(s) : Mukesh Sharma

[email protected]

International Journal of Allied Medical Sciences and Clinical Research, Vol. 2 No. 1 (2014): 2014 Volume 2- Issue -1
Article Published : July 31, 2020

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Abstract

can be divided into two types according to presence or absence of sugar in urine viz. ZIABETUS SADA(Ziabetus Barid)  and ZIABETUS SHAKRI (Ziabetus Har). Diabetes Mellitus (Zayabetus) is one of the most important lifestyle related disorders that is mostly widespread in urban areas. The Unani system of originated in Greece. Hippocrates is known as the father of Unani system of medicine. The theoretical framework of Unani system of medicine is based on his teachings.After a number of other greek Scholars enriched the system considerably. Of the Galen (131-120 AD) stands out as the one who established its foundation on which Arab physicians like Rhazes (850-925 AD) and Avicenna (980-1037 AD) constructed an imposing edifice. The number of people around the World suffering from diabetes has skyrocketed in the last two decades, from 30 to 230 millions. East Asian countries have the highest burden of diabetes. India comprises of 85% of the adult population of Southeast Asia and therefore the major contribution to diabetic population in South East Asia is from India. It has been estimated that India, considered as the diabetic capital of the World with more than 32 milion diabetes patients would continue to lead even at 2030 ith a whopping 80 million diabetics. So many brands and formulations are available in market like-Diab-Eaze,Dolabi Tablets,Herbo Diabecon,Gurmar Capsules,Neem Capsules,Fenugreek Capsules,Safoof- E- Ziabetes- Dulabi.

Keywords

Unani formulation Zayabetus Fenugreek Safoof-E-Ziabetes

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References
    [1] Sharma KA, Kumar R, Mishra A et.al;Problems associated with clinical trials of Ayurvedic medicines; Reu Bras Farmacogn Braz J Pharmacogn 2010; 20(2):276-281
    [2] Subobd S Production and productivity of Medicinal and Aromatic plants in Mughal India; A study of contemporary Texts. Asian Agri History 2010;15(1):3-12
    [3] Source : Dabur Research Organization Survey
    [4] Sina I.AI Quanoon Fil Tib. Vol. 2nd(Urdu translation by Kantoori G H), Idara Kitab Alshifa, Delhi, 1119-25, 2007.
    [5] Ahmad I. Kulliyate Asri. New Public Press Delhi, 32-85,1983.
    [6] Husain A, Sofi GD, Tajauddin et.al. Unani System Of Medicine- Introduction and Challenges. Medical Journal of Islamic World Academy of Sciensec 2010; 18(1): 27-30.
    [7] INTERNET [www.herbalniamaths.com/um.htm]
    [8] Global status of unani medicine by- Prof. Anis A. Ansari , Advicer (Unani Medicine)Ministry of Health and Family Welfare, Department of AYUSH Government of India
    [9] A Ishtiyaq: Kulliyat-e-Asri, New Public Press Delhi, 34-83,1983
    [10] Source : Dabur Research Organization Survey.
    [11] Abubakr Muhammed Bin Zakariya Razi: Ktab-ul-Mansoori, CCRM, New Delhi, 52, 1991.
    [12] Ibn Sina: AL-Qanum fil-Tibb, Jaia hamdard, New Delhi, vol: 2, 1-37, 1998.
    [13] Abial-Walid Mohammad bin Ahmad bin Mohammad bin Rushd, Kitab Al-Kuliyat, Literary Research Unit Lucknow, CCRUM, 365, 1965.
    [14] Ibn-e-Abbas Majoosi, Tarjuma Kamilussalaah, Munshi nawal kishore Lucknow, vol:2, 600-604, 1889.
    [15] Ibn Sina, Al-Qanun fil-Tibb, Jamia hamdard New Delhi, vol:4, 1-251, 2002.
    [16] National Formulary of Unani Medicine, Government of India Ministry of Health and Family Welfare New Delhi, 1-250, 1981.
    [17] Tabri AH: Firdousul Hikmat, Maktaba Munshi Nawal kishore Lucknow,1st edition,1928.
    [18] Kabiruddin: Bayaz-e-kabir,4th edition, 2nd vol, Hikmat Book Depo Haidrabad Dakan, 1938.
    [19] CCIM (http://ccimindia.org/index.html)
    [20] TraditionalKnowledgeDigitalLibrary(http://www.tkdl.res.in/tkdl/langdefault/common/) website.
    [21] Know Instances of Patenting on the UES of Medicinal Plants in India" (http://pib.nic.in/release/release.asp? relid=61511) PIB, Ministry of Environment and Forests. May 6, 2010. http://pib.nic.in/release/release.asp? relid=61511.
    [22] Central Council for Research in Unani Medicine (CCRUM)"
    [23] (http://www.tkdl.res.in/tkdl/LangSpanish/Unani/Una_ccrum.asp?GL=)Traditional KnowledgeDigitalLibrary. http://www.tkdl.res.in/tkdl/LangSpanish/Unani/Una_ccrum.asp?GL=.
    [24] Research and Development: Central Council for Research in Unani Medicine (CCRUM)" (http://www.crism.net/research.htm) . Centre for Research in Indian Systems of Medicine, (CRISM). http://www.crism.net/research.htm.
    [25] Rahman, SZ; Latif, A; Khan, RA (Dec 2008). "Importance of pharmacovigilance in Unani system of medicine" (http://www.ijp-online.com/text.asp?2008/40/7/17/40238) . Indian J Pharmacol. 40 (7): 17–20.
    [26] Qarshi, Jami-ul-Hikmat. Vol 2nd Lahore: Shaikh Mohammad Bashir and sons; pg 378-379.
    [27] Khan M Ajmal.”Haziq”. Delhi: Jasem Book Depot; P 387-90.
    [28] [http://www.gyan_unlimited.com/health/unani-treatment-for-diabetes-mellitus-unani-medicine-for-diabetes-zayabetus/4290/]
    [29] Santora M, Experts raise alarm as diabetes hits millions, The Times of India, 12 June 2006, 13.
    [30] Ramachandran A, Epidemiology of Diabetes in India-Three Decades of Research, JAPI, 53(2005) 34.
    [31] Rao BNP,Kumar DRA, Kulkarni KR, Bhatavadekar PD and Nagabhushan KH, Audio vestibular functions in diabetic patients, Indian Med Gaz, 139 (10) (2005) 418.
    [32] Haslett C& Chilves ER, Davidson’s Principles & Practice of Medicine, 19th edn, (Churchill livingstone, Elsevier Science Ltd, New York),2002,644 & 656.
    [33] Ghani MAA, Tripathi D & DeFronzo RA, Contribution of beta- cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose, Diabetes Care, 29 (5) (2006) 1130.
    [34] Kabiruddin M, Makhzan-ul-Mufradat, (Year of publication and name of publisher not known), 181-182 & 562-564
    [35] Internet [riderinternational.ecrater.com/P/7927058/diabeaze-all-natural-herbal-anti-diabetic_capsules]
    [36] Diabeaze.com
    [37] www.hamdard.com.bd/products/products-list/97-dolabi
    [38] www.herbalstrength.in/buy/herbo-diabecon-capsule-72515
    [39] satvikshop.com/ayurveda/diabetes/hashmi-herbal-diabetes-treatment-herbo
    [40] diabecon/20059/p-B1012725
    [41] www.cher4life.com/product-profile/4 life-gurmar.PDF
    [42] Internet[http://www.delhvi.com/download.php?f=1347599760.pdf].
    [43] National Formulary of Unani Medicine (NFUM), Government of India, Department of Indian System of Medicine and Homeopathy, Part- 2, The Controller of Publication Civil Lines, New Delhi, 2000, 89.
    [44] Joseph B, Raj SJ, Phytopharmacological and phytochemical properties of three Ficus species- an overview, International Journal of Pharma and Bio Sciences, 1(4), 2010, 246-53.
    [45] Karmarkar UK, Rahman MA, Roy DN, Sandhu SK, Ali ME, Chemical and biological investigations of Coriandrum sativum Linn, International Journal of Pharmaceutical Sciences and Research, 2(4), 2011, 999-1006.
    [46] Ali Z, Siddiqui HL, Mahmud S, Waheed A, Hameed S, 4, 4-dimethylsterols, 4-methylsterols and 4-demethylsterols of Mangifera indica kernel fat, Pakistan Journal of Scientific Research, 60(1-2), 2008, 34-39.
    [47] Ahmed R, Ifzal SM, Saifuddin A, Mohammad N, Studies on Punica Granatum - isolation and identification of some constituents from the seeds of Punica Granatum, Pakistan Journal of Pharmaceutical Science, 8(1), 1995, 69-71.
    [48] Wang R, Wang W, Wang L, Liu R, Ding Y, Du L, Constituents of the flowers of Punica granatum, Fitoterapia, 77, 2006, 534–37.
    [49] Best MM, Duncan CH, Modification of abnormal serum lipid patterns in atherosclerosis by administration of sitosterol, Annals of Internal Medicine. 45, 1956, 614-22.
    [50] Becker M, Staab D, Von Bergmann K, Long-term treatment of severe familial hypercholesterolemia in children: Effect of sitosterol and bezatibrate, Pediatrics, 89, 1992, 138-42.
    [51] Awad, AB, Chen YC, Fink CS, Hennessey T, Beta-sitosterol inhibits HT-29 human colon cancer cell growth and alters membrane lipids, Research, 16(5A), 1996, 2797-804.
    [52] Desai F, Ramanathan M, Fink CS, Wilding GE, Weinstock-Guttman B, Awad AB, Comparison of the immunomodulatory effects of the plant sterol beta-sitosterol to simvastatin in peripheral blood cells from multiple sclerosis patients, International journal of
    [53] Immunopharmacology, 9(1), 2009, 153-57.
    [54] Jamaluddina F, Mohamed S, Lajis MN, Hypoglycaemic effect of Parkia speciosa seeds due to the synergistic action of ?-sitosterol and Stigmasterol, Food Chemistry, 49(4), 1994, 339-45.
    [55] ZillurRahman, Syed,(2010), Kitab Al Murakkabat: Ibn Sin Academy, Dodhpur, Aligarh.pg.no.131,133
    [56] Kabeeruddin,Hkm M.,(1935).Bayazekabeer:Hikmat book depot; Hydrabad,Deccan; pg.no.107.
    [57] Jeelani, Gulam; (1995). KitabulMurakkbat AlMaroof Makhzanul murakkbat: Aijaz publishing house, New Delhi pg.no.270.
    [58] Shareef khan,M,( 2006). BayazeKhas AlMaruf Ilajul Amraaz: Aijaz publishing house, New Delhi pg.no.773.
    [59] www.articlebase.com/findarticles.php?9=Jawarish+Zarooni+sada+A+herbal+unani+nephroprotective+tonic.
    [60] www.unani_herbal.org/diabetes.htm
    [61] trade.indiamart.com/details.mp?offer=2351964173
    [62] Internet[http://www.delhvi.com/download.php?f=1347599760.pdf]
    [63] www.delhvi.com/medicine-Qurs-kushta-Baiza-Murgh-view-457-html
    [64] www.delhvi.com/medicine-shugar-No-view-126.html
    [65] www.baqaicares.com/diabetes-care-tablets.htm
    [66] www.delhvi.com/medicine-qurs-kushta-Zamarrud_view-483.html
    [67] www.hamdard.com.bd/products/product-list/103-garlitab
    [68] Diabetes Herbal and Natural Therapies. Uk. Thiruvelan - Healthy-ojas, Hand book of Ayurveda and Unani. India, and others Books.
    [69] www.delhvi.com/medicine-Jawarish-mastagi-view-431.html
Read More

References


[1] Sharma KA, Kumar R, Mishra A et.al;Problems associated with clinical trials of Ayurvedic medicines; Reu Bras Farmacogn Braz J Pharmacogn 2010; 20(2):276-281
[2] Subobd S Production and productivity of Medicinal and Aromatic plants in Mughal India; A study of contemporary Texts. Asian Agri History 2010;15(1):3-12
[3] Source : Dabur Research Organization Survey
[4] Sina I.AI Quanoon Fil Tib. Vol. 2nd(Urdu translation by Kantoori G H), Idara Kitab Alshifa, Delhi, 1119-25, 2007.
[5] Ahmad I. Kulliyate Asri. New Public Press Delhi, 32-85,1983.
[6] Husain A, Sofi GD, Tajauddin et.al. Unani System Of Medicine- Introduction and Challenges. Medical Journal of Islamic World Academy of Sciensec 2010; 18(1): 27-30.
[7] INTERNET [www.herbalniamaths.com/um.htm]
[8] Global status of unani medicine by- Prof. Anis A. Ansari , Advicer (Unani Medicine)Ministry of Health and Family Welfare, Department of AYUSH Government of India
[9] A Ishtiyaq: Kulliyat-e-Asri, New Public Press Delhi, 34-83,1983
[10] Source : Dabur Research Organization Survey.
[11] Abubakr Muhammed Bin Zakariya Razi: Ktab-ul-Mansoori, CCRM, New Delhi, 52, 1991.
[12] Ibn Sina: AL-Qanum fil-Tibb, Jaia hamdard, New Delhi, vol: 2, 1-37, 1998.
[13] Abial-Walid Mohammad bin Ahmad bin Mohammad bin Rushd, Kitab Al-Kuliyat, Literary Research Unit Lucknow, CCRUM, 365, 1965.
[14] Ibn-e-Abbas Majoosi, Tarjuma Kamilussalaah, Munshi nawal kishore Lucknow, vol:2, 600-604, 1889.
[15] Ibn Sina, Al-Qanun fil-Tibb, Jamia hamdard New Delhi, vol:4, 1-251, 2002.
[16] National Formulary of Unani Medicine, Government of India Ministry of Health and Family Welfare New Delhi, 1-250, 1981.
[17] Tabri AH: Firdousul Hikmat, Maktaba Munshi Nawal kishore Lucknow,1st edition,1928.
[18] Kabiruddin: Bayaz-e-kabir,4th edition, 2nd vol, Hikmat Book Depo Haidrabad Dakan, 1938.
[19] CCIM (http://ccimindia.org/index.html)
[20] TraditionalKnowledgeDigitalLibrary(http://www.tkdl.res.in/tkdl/langdefault/common/) website.
[21] Know Instances of Patenting on the UES of Medicinal Plants in India" (http://pib.nic.in/release/release.asp? relid=61511) PIB, Ministry of Environment and Forests. May 6, 2010. http://pib.nic.in/release/release.asp? relid=61511.
[22] Central Council for Research in Unani Medicine (CCRUM)"
[23] (http://www.tkdl.res.in/tkdl/LangSpanish/Unani/Una_ccrum.asp?GL=)Traditional KnowledgeDigitalLibrary. http://www.tkdl.res.in/tkdl/LangSpanish/Unani/Una_ccrum.asp?GL=.
[24] Research and Development: Central Council for Research in Unani Medicine (CCRUM)" (http://www.crism.net/research.htm) . Centre for Research in Indian Systems of Medicine, (CRISM). http://www.crism.net/research.htm.
[25] Rahman, SZ; Latif, A; Khan, RA (Dec 2008). "Importance of pharmacovigilance in Unani system of medicine" (http://www.ijp-online.com/text.asp?2008/40/7/17/40238) . Indian J Pharmacol. 40 (7): 17–20.
[26] Qarshi, Jami-ul-Hikmat. Vol 2nd Lahore: Shaikh Mohammad Bashir and sons; pg 378-379.
[27] Khan M Ajmal.”Haziq”. Delhi: Jasem Book Depot; P 387-90.
[28] [http://www.gyan_unlimited.com/health/unani-treatment-for-diabetes-mellitus-unani-medicine-for-diabetes-zayabetus/4290/]
[29] Santora M, Experts raise alarm as diabetes hits millions, The Times of India, 12 June 2006, 13.
[30] Ramachandran A, Epidemiology of Diabetes in India-Three Decades of Research, JAPI, 53(2005) 34.
[31] Rao BNP,Kumar DRA, Kulkarni KR, Bhatavadekar PD and Nagabhushan KH, Audio vestibular functions in diabetic patients, Indian Med Gaz, 139 (10) (2005) 418.
[32] Haslett C& Chilves ER, Davidson’s Principles & Practice of Medicine, 19th edn, (Churchill livingstone, Elsevier Science Ltd, New York),2002,644 & 656.
[33] Ghani MAA, Tripathi D & DeFronzo RA, Contribution of beta- cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose, Diabetes Care, 29 (5) (2006) 1130.
[34] Kabiruddin M, Makhzan-ul-Mufradat, (Year of publication and name of publisher not known), 181-182 & 562-564
[35] Internet [riderinternational.ecrater.com/P/7927058/diabeaze-all-natural-herbal-anti-diabetic_capsules]
[36] Diabeaze.com
[37] www.hamdard.com.bd/products/products-list/97-dolabi
[38] www.herbalstrength.in/buy/herbo-diabecon-capsule-72515
[39] satvikshop.com/ayurveda/diabetes/hashmi-herbal-diabetes-treatment-herbo
[40] diabecon/20059/p-B1012725
[41] www.cher4life.com/product-profile/4 life-gurmar.PDF
[42] Internet[http://www.delhvi.com/download.php?f=1347599760.pdf].
[43] National Formulary of Unani Medicine (NFUM), Government of India, Department of Indian System of Medicine and Homeopathy, Part- 2, The Controller of Publication Civil Lines, New Delhi, 2000, 89.
[44] Joseph B, Raj SJ, Phytopharmacological and phytochemical properties of three Ficus species- an overview, International Journal of Pharma and Bio Sciences, 1(4), 2010, 246-53.
[45] Karmarkar UK, Rahman MA, Roy DN, Sandhu SK, Ali ME, Chemical and biological investigations of Coriandrum sativum Linn, International Journal of Pharmaceutical Sciences and Research, 2(4), 2011, 999-1006.
[46] Ali Z, Siddiqui HL, Mahmud S, Waheed A, Hameed S, 4, 4-dimethylsterols, 4-methylsterols and 4-demethylsterols of Mangifera indica kernel fat, Pakistan Journal of Scientific Research, 60(1-2), 2008, 34-39.
[47] Ahmed R, Ifzal SM, Saifuddin A, Mohammad N, Studies on Punica Granatum - isolation and identification of some constituents from the seeds of Punica Granatum, Pakistan Journal of Pharmaceutical Science, 8(1), 1995, 69-71.
[48] Wang R, Wang W, Wang L, Liu R, Ding Y, Du L, Constituents of the flowers of Punica granatum, Fitoterapia, 77, 2006, 534–37.
[49] Best MM, Duncan CH, Modification of abnormal serum lipid patterns in atherosclerosis by administration of sitosterol, Annals of Internal Medicine. 45, 1956, 614-22.
[50] Becker M, Staab D, Von Bergmann K, Long-term treatment of severe familial hypercholesterolemia in children: Effect of sitosterol and bezatibrate, Pediatrics, 89, 1992, 138-42.
[51] Awad, AB, Chen YC, Fink CS, Hennessey T, Beta-sitosterol inhibits HT-29 human colon cancer cell growth and alters membrane lipids, Research, 16(5A), 1996, 2797-804.
[52] Desai F, Ramanathan M, Fink CS, Wilding GE, Weinstock-Guttman B, Awad AB, Comparison of the immunomodulatory effects of the plant sterol beta-sitosterol to simvastatin in peripheral blood cells from multiple sclerosis patients, International journal of
[53] Immunopharmacology, 9(1), 2009, 153-57.
[54] Jamaluddina F, Mohamed S, Lajis MN, Hypoglycaemic effect of Parkia speciosa seeds due to the synergistic action of ?-sitosterol and Stigmasterol, Food Chemistry, 49(4), 1994, 339-45.
[55] ZillurRahman, Syed,(2010), Kitab Al Murakkabat: Ibn Sin Academy, Dodhpur, Aligarh.pg.no.131,133
[56] Kabeeruddin,Hkm M.,(1935).Bayazekabeer:Hikmat book depot; Hydrabad,Deccan; pg.no.107.
[57] Jeelani, Gulam; (1995). KitabulMurakkbat AlMaroof Makhzanul murakkbat: Aijaz publishing house, New Delhi pg.no.270.
[58] Shareef khan,M,( 2006). BayazeKhas AlMaruf Ilajul Amraaz: Aijaz publishing house, New Delhi pg.no.773.
[59] www.articlebase.com/findarticles.php?9=Jawarish+Zarooni+sada+A+herbal+unani+nephroprotective+tonic.
[60] www.unani_herbal.org/diabetes.htm
[61] trade.indiamart.com/details.mp?offer=2351964173
[62] Internet[http://www.delhvi.com/download.php?f=1347599760.pdf]
[63] www.delhvi.com/medicine-Qurs-kushta-Baiza-Murgh-view-457-html
[64] www.delhvi.com/medicine-shugar-No-view-126.html
[65] www.baqaicares.com/diabetes-care-tablets.htm
[66] www.delhvi.com/medicine-qurs-kushta-Zamarrud_view-483.html
[67] www.hamdard.com.bd/products/product-list/103-garlitab
[68] Diabetes Herbal and Natural Therapies. Uk. Thiruvelan - Healthy-ojas, Hand book of Ayurveda and Unani. India, and others Books.
[69] www.delhvi.com/medicine-Jawarish-mastagi-view-431.html
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