A review on adverse drug reactions of antidiabetic drugs

Abstract

India had 69.2 million people living with diabetes (8.7%) as per the 2015 data by WHO. of these, it remained undiagnosed in more than 36 million people. Effective management of diabetes and an adverse effect of drugs is associated with lower morbidity, mortality, and health care. Over time, high blood sugar can seriously compromise every major organ system in the body, causing heart attacks, strokes, nerve damage, kidney failure, blindness, impotence and infections that can lead to amputations. Treatment for diabetes includes insulin and oral antidiabetic agents. Along with these drugs, diabetic patients generally take medications to treat dyslipidemia, an antihypertensive drug, and antiplatelet therapy. Adverse drug reaction associated with antidiabetic treatment are hypoglycemia, hypoglycemic coma, hypersensitivity, hepatotoxicity, drug induced erythema multiforme, photodermatitis etc. So, it is need of the new era to aware people about the adverse effects of an antidiabetic drug. It is necessary to educate the patient on their medications and potential adverse events associated with each medication to limit potential treatment complications. The main objective of the article is to increase awareness about the drugs used in diabetes treatment, its consequences, and adverse drug reaction reporting.