Adverse Drug Reaction Study in Tertiary Care Hospital

Abstract

The prospective and observational non-interventional study was conducted in Aware Global Hospital. In-patients treated with drugs in the various clinical departments of hospital were reviewed on daily basis. All suspected ADRs will be suitably assessed for causality, severity, preventability and predictability. The results were presented as number and percentage. Among the 1129 cases (males and females), a total of 139 ADRs were detected, an overall incidence of 46.64% adverse drug reactions in inpatients. The prevalence of ADR mostly occurred in the age group between 31-60 years (46%) and in female patients (56.83%). The most frequent adverse drug reaction were due to Antibiotics (46%), Anti-Tubercular drugs (5.75%), Oral-Hypoglycemics (5.04%), NSAIDs (5.03%). Adverse drug reactions were a common occurrence and awareness about them was found to be essential for early detection and prevention. The healthcare system can promote the spontaneous reporting of ADR to Pharmacovigilance centre's for ensuring safe drug use and patient care. Our study suggests that there is a need of intensive ADR monitoring in tertiary care hospital for early detection and prevention to ensure the patient safety.