A case report on Pre-B Acute Lymphoblastic Leukemia

Abstract

Lymphoid leukemias are a group of leukemias affecting circulating lymphocytes. Acute lymphoblastic leukemia (ALL) is a malignant disease of the bone marrow in which early lymphoid precursors proliferate and replace the normal hematopoietic cells of the marrow. ALL is the most common type of leukemia in children and little is known of its origin. It presents with either symptoms relating to direct infiltration of the marrow or symptoms relating to the decreased production of normal marrow elements. Fever is one of the most common symptoms of ALL. Precursor B-cell lymphoblastic leukemia is a form of lymphoid leukemia in which too many B-cell lymphoblasts (immature white blood cells) are found in the blood and bone marrow. Diagnosis of ALL generally requires Demonstration of ?20% bone marrow lymphoblasts, Morphologic assessment of Wright/Giemsa–stained bone marrow aspirate smears, Hematoxylin and eosin stained bone marrow core biopsy and clot sections. Bone marrow aspiration and biopsy are the definitive diagnostic tests to confirm the diagnosis of leukemia. We report a case of, 32 years old female suffering from Pre-B ALL since 5 years. She received Dr. Appa Rao’s treatment and was completely free of any pains and symptoms.