Diagnosis and management of deep venous thrombosis

Abstract

There is high incidence of venous thromboemoblism, comprising of deep vein thrombosis and pulmonary embolism, in hospitalized patients. The need for systemic thromborophylaxis is essential, especially in patient with inherited or acquired of postoperative deep vein thrombosis and pulmonary embolism. Similar animal experiments could end the present exclusive reliance on statistical analysis of data from large patient cohorts to evaluate prophylactic regimes. The reduction of need for such (usually retrospective) analyses could enable rationally-based clinical trials of prophylactic methods to be conducted more rapidly, and the success of such trials would lead to decreased incidences of DVT-related mortality and morbidity. Used in treatment prophylactic or therapeutic doses of anticoagulants, may present of surgery. General or regional anaesthesia may be considered depending on the type and degree of anticoagulation as judged by investigation. The dilemma regarding the type of anaesthesia can be solved if the anaesthesiologist is aware of the pharmacokinetics of drugs affecting haemostasis. The anaesthesiologist must keep abreast with latest developments of methods and drugs used in the prevention and management of venous thromboembolism and implications in the conduct of anaesthesia.