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Antibacterial activity of Andrographis Paniculata L.
Corresponding Author(s) : Dr. J.Jayachitra
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 4 No. 2 (2016): 2016 Volume 4- Issue -2
Abstract
Ethanolic extract and chloroformic extracts of Andrographis Paniculata leaves was investigated for antibacterial activities.
Methods
The well diffusion method was followed for antibacterial assay.Antibacterial activity of the leaves extract using well diffusion method according to Bauer et al.,.(1996). In this disc was prepared by using whatmann No.1 filter paper. Then, the filter paper disc of 5mm diameter were sterilized and soaked in the different concentration of plant extract. Results
The antibacterial activity of Andrographis Paniculata was tested against 4 species of bacteria, viz, Staphyloccus, Streptococcus, Bacillus pseudomonas and E.Coli.
Conclusion
Aqueous ethanolic extract and chloroformic extracts of leaves was screened for their antibacterial potential. The zone of inhibition was seen to be largest when chloroform extract was used.
Keywords
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Baron (1982). Normal flora associated with various are of the body pp.178.
[2]. Eugene, Nester; 1995 Microbiology edition. JP. 521-23. Exp Pharnacol. Physiol. 27,358-363.
[3]. Bone, k., (1998). The story of Andrographis paniculata, a new “ immune system”
[4]. Bisno (1976). Streptococcal infectious of skin and soft tissue, N. Engl. J. Med. 334:240
[5]. Bisbe (1988). Pseudomonas aeuruginosa bacteremia: invariant and multivarient analysis of factor influencing progness in 133, Rev infect dis 10:629-635.
[6]. Bodey(1985). Pseudomonas bacteremia; Retrospective of 410 episodes. Arch. Intem med .145:1621-1629.
[7]. Subba Rao(1962). Ind.J. Pharm 24:134-138.
[8]. Bauer, AW., Kirby,wmm., sherries, JC., Turck, M., AM J Clin path 1996;45:493
[9]. Havesteen, B., (1991). Flavonoids, a class of natural production of high pharmacological potency. Biochem. Pharmacol. 32:114`-1148. Herb. Nutrition and healing. Step:3,4,8,9 (review)
[10]. Hartmann, T., (1991). Alka loids in herbivores: Their Interaction with Secondary Plant Metabolites, 2nd edn., Academic press,San Diego, 1:9.
[11]. Prajapathi,Purohit, Sharma and Kumar. (2002). Curative properties of medicinal plants. A hand book of medicinal plants.p-359.47:499-503.
[12]. Chang RS,Ding L and Chen GQ., (1991). Dehyro andrographolide succinic acid monoester as an inhibitor against the human immuno deficiency proc soc Exp med 197:59-66.
[13]. Deng, N.S.,(1978). Further studies on neuropharmacological actions of acorus oil. Arch Int Pharmacodyn Ther Apr; 172(2):356-65
[14]. Gupta KK, Thaneja SC and Dhar KL. (1990). Flavonoids glucoside of Andrographis paniculata. Indian journal of chemistry 35B:512-513.
References
[2]. Eugene, Nester; 1995 Microbiology edition. JP. 521-23. Exp Pharnacol. Physiol. 27,358-363.
[3]. Bone, k., (1998). The story of Andrographis paniculata, a new “ immune system”
[4]. Bisno (1976). Streptococcal infectious of skin and soft tissue, N. Engl. J. Med. 334:240
[5]. Bisbe (1988). Pseudomonas aeuruginosa bacteremia: invariant and multivarient analysis of factor influencing progness in 133, Rev infect dis 10:629-635.
[6]. Bodey(1985). Pseudomonas bacteremia; Retrospective of 410 episodes. Arch. Intem med .145:1621-1629.
[7]. Subba Rao(1962). Ind.J. Pharm 24:134-138.
[8]. Bauer, AW., Kirby,wmm., sherries, JC., Turck, M., AM J Clin path 1996;45:493
[9]. Havesteen, B., (1991). Flavonoids, a class of natural production of high pharmacological potency. Biochem. Pharmacol. 32:114`-1148. Herb. Nutrition and healing. Step:3,4,8,9 (review)
[10]. Hartmann, T., (1991). Alka loids in herbivores: Their Interaction with Secondary Plant Metabolites, 2nd edn., Academic press,San Diego, 1:9.
[11]. Prajapathi,Purohit, Sharma and Kumar. (2002). Curative properties of medicinal plants. A hand book of medicinal plants.p-359.47:499-503.
[12]. Chang RS,Ding L and Chen GQ., (1991). Dehyro andrographolide succinic acid monoester as an inhibitor against the human immuno deficiency proc soc Exp med 197:59-66.
[13]. Deng, N.S.,(1978). Further studies on neuropharmacological actions of acorus oil. Arch Int Pharmacodyn Ther Apr; 172(2):356-65
[14]. Gupta KK, Thaneja SC and Dhar KL. (1990). Flavonoids glucoside of Andrographis paniculata. Indian journal of chemistry 35B:512-513.