4-chloro-6-methoxy-2-styryl quinoline, its synthesis and antibacterial activity
Corresponding Author(s) : B.Deepthi
ijamscr@gmail.com
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 4 No. 1 (2016): 2016 Volume - 4 Issue-1
Abstract
P-anisidine on treatment with ethyl aceto acetate in ethanol refluxing for 4 hrs.gave ethyl-3-[4-methoxyphenyl) imino] butanol which is on thermal cyclization in hot propylene glycol at 1000c gave 4-hydroxy-6-methoxy-2-methyl quinoline. The latter on heating with POCl3 gave 4-chloro-6-methox-2-methyl quinoline which on treatment with benzaldehyde gave corresponding 4-chloro-6-methoxy-2-styryl quinoline. The product have been characterized based on the spectral data and have been evaluated for its antibacterial activity
1.
B.Deepthi. 4-chloro-6-methoxy-2-styryl quinoline, its synthesis and antibacterial activity. Int. J. of Allied Med. Sci. and Clin. Res. [Internet]. 2020 Aug. 5 [cited 2025 Nov. 19];4(1):151-4. Available from: https://ijamscr.com/ijamscr/article/view/250
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