Formulation Development and Evaluation of Mini-Tablets in Enteric Capsule Drug Delivery Technology of Diclofenac Sodium

Abstract

Enteric capsule drug delivery technology (ECDDT) was developed to allow for fast GI tract release without coating and full enteric protection during oral route of administration Enteric capsule drug delivery technology eliminated the need for enteric coatings preparations and application process which means that development time can be shorter and program risk can be lower. Pellets that are easy to make have low porosity and all the same size and shape have smooth surface and don’t change from batch to batch can be turn into mini tablets which another to way to take medicine, the current study aimed to create a mini tablet within the Enteric capsule drug delivery technology considering the advantage of Enteric capsule drug delivery technology and mini tablets the Diclofenac sodium served as a model drug to elucidate the drug release profile and drug kinetics and stability assessment.