A Case Report on Atropine Induced CNS Side Effects and Tachycardia

Abstract

Atropine is an anti-cholinergic, prototype of drug obtained from Atropa Belladonna. It mainly blocks the muscarinic receptors which place a major role in performance of the brain for learning, memory and orientation. In the therapeutic dose, atropine has a mild CNS stimulant effect but large doses can  produce excitement, restlessness, agitation , hallucinations, coma and death. In therapeutic dose of atropine produces tachycardia through the blockage of M₂ receptors of the heart. The uses of atropine  includes  brad arrhythmias, Severe bradycardia, organophosphate  poisoning ,  1st degree A-V block,  salivary and bronchial secretion reduction. the extreme doses of atropine can causes the  tachycardia, delirium,  coma, flushed and hot skin, blurred vision, excitement, restlessness, hallucinations  and ataxia. Here in this case report, a 30 years old female  patient was developed  excitement, hallucinations, restlessness, blurring of vision, photophobia, tachycardia, palpitation medullary paralysis and ECG abnormalities due to the atropine administration.