Extraction, Preliminary Phytochemical Screening & Antibacterial Activity of Terminalia chebula Fruit

Abstract

The aim of the current research investigation was to perform the extraction, preliminary phytochemical screening and to evaluate the invitro antibacterial activity of fruit of Terminalia chebula. The present study includes the extraction with methanol and screening of various active chemical constituents’ of fruit of Terminalia chebula that exhibit anti-microbial activity. The fruit of Terminalia chebula was screened for estimation of phytochemical standards like: phenolic, flavonoid, tannins, carbohydrates, steroids, glycosides and mucilage content. In the current investigation, Methanol extractions are subjected to invitro antibacterial activity using standard procedures. The investigation was accomplished using agar well diffusion method. Outcomes of Phytochemical analysis of Terminalia chebula revealed that the plant possesses strong antibacterial potentials. The zone of inhibition for methanol extract against Staphylococcus aureus at 100μL was found to be 4.8 mm. The zone of inhibition for methanol extract at 100μL against E.coli was found to be 3.0 mm and The zone of inhibition for standard drug ampicillin was found to be 6.2mm.The existence of the bioactive compounds in the fruit may be responsible for antibacterial properties of Terminalia chebula that form the basis of their use in herbal medicine in India. The evidence found from contemporary study deliver valuable data that will be supportive in identifying and to perform upcoming research in future.