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Anti-Bacterial Activity and Formulation of Cream from the Medicinal Plant: Nyctanthes Arbor-Tristis
Corresponding Author(s) : B.V. Shilpa
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 12 No. 2 (2024): 2024 Volume -12 - Issue 2
Abstract
Nyctanthes arbor-tristis is well known Indian medicinal plant. Qualitative analysis was carried out to identify the different classes of secondary metabolites in various chemical extracts such as water and methanol. Qualitative analysis of the extracts proved the presence of phytochemicals such as Saponin, Tannin, Flavonoid, Steroid, Terpenoid, Quinine, Coumarin, Emodin and Gum and Mucilage. The pharmacological interest of these compounds, coupled with the use of this plant in traditional medicine prompted the authors to check for its possible antibacterial activity. The extract ethanol were found to possess maximum potency against infectious pathogens like gram(+ve)Staphylococcus aureus, Bacillus subtilis and gram(+ve) Escherichia coli, Pseudomonas aeruginosa. The zone of inhibition was observed after conformed with cell diffusion method with selected bacteria. Minimum inhibitory concentrations of the extracts were found to be significant. The obtained results provide a support for the use of this plant in traditional medicine and its further investigation.
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- Abubakar, M.S. Isolation of Kaempferide and Antimicrobial Activity of Fractions of Aqueous Ethanol Extract of ThesiumViride. Afr. J. Pharm. Res. Dev., 2016; 8(1): 19-23.
- The Pharmaceutical Codex, (1979). 11th Ed. The Pharmaceutical Press, Her Majesty's
- Opinde HR, Gatheri GW, Nyamache AK. Antimicrobial evaluation of crude methanolic leaf extracts from selected medicinal plants against Escherichia coli. J. Bacteriol. Parasitol. 2016;7:272.https://www.academia.edu/download/79830199/Antimicrobial_Evaluation_of_Crude_Methanolic_Leaf_Extracts_from_Selected.pdf
- Tiwari SS. Medicinal Plants-Perspectives and Needs. J Pharmacogn Nat Prod. 2016;Vol 2, pp105.
- Bouyahya A, Abrini J, El-Baabou A, Bakri Y, Dakka N. Determination of phenol content and antibacterial activity of five medicinal plants ethanolic extracts from North-West of Morocco. J Plant PatholMicrobiol. 2016 Jun 22;7(342):2.
- UNESCO. Culture and Health, Orientation Texts – World Decade for Cultural Development 1988 – 1997, Document CLT/DEC/PRO – 1996, Paris, France 19960.
- Mahato SB, Sen S. Advances in triterpenoid research, 1990–1994. Phytochemistry. 1997 Apr 1;44(7):1185-236.https://www.sciencedirect.com/science/article/pii/S0031942296006395
- Aliyu, A.B., Musa, A.M., Abdullahi, M.S.,Ibrahimi, H and Oyewale, A.O. Phytochemical screening and antibacterial activities of Vernoniaambigua, Vernoniablumeoides and Vernoniaoocephala (Asteraceae). Acta Polo. Pharm. 2011; 68(1): 67-73.
- Ashish, A., Mohini, K. and Abhiram, R. Preparation and evaluation of polyherbal cosmetic cream. Scholars Res. Libr., 2013; 5(1): 83-88.
- Barry, B.W.: Topical preparations. In: Pharmaceutics, The Science of Dosage Form Design. Ed.: Aulton ME. Churchill Livingstone, Edinburgh, International student edition, 1999; 381-411.
- Builders, M.I., Wannang, N.N., Ajoku, G.A., Builders, P.F., Orisadipe, A and Aguiyi, J.C. Evaluation of the Antimalarial Potential of VernoniaambiguaKotchy and Peyr (Asteraceae). Int. J. Pharmacol., 2011; 7(2): 238- 247.
- Chen, M.X., Alexander, K.S., and Baki, G. Formulation and Evaluation of Antibacterial Creams and Gels Containing Metal Ions for Topical Application. J. Pharm., 2016; Article ID 5754349, 10 pages.
- Hossain, M.S., Hossain, M.M., Zaman, S., Mondal, M. and Rana, S. Phytochemical screening, antioxidant and antimicrobial activities of leaf extracts of Randiauliginosa. World J Pharm Sci, 2014; 2(12): 1687-1696.
References
Abubakar, M.S. Isolation of Kaempferide and Antimicrobial Activity of Fractions of Aqueous Ethanol Extract of ThesiumViride. Afr. J. Pharm. Res. Dev., 2016; 8(1): 19-23.
The Pharmaceutical Codex, (1979). 11th Ed. The Pharmaceutical Press, Her Majesty's
Opinde HR, Gatheri GW, Nyamache AK. Antimicrobial evaluation of crude methanolic leaf extracts from selected medicinal plants against Escherichia coli. J. Bacteriol. Parasitol. 2016;7:272.https://www.academia.edu/download/79830199/Antimicrobial_Evaluation_of_Crude_Methanolic_Leaf_Extracts_from_Selected.pdf
Tiwari SS. Medicinal Plants-Perspectives and Needs. J Pharmacogn Nat Prod. 2016;Vol 2, pp105.
Bouyahya A, Abrini J, El-Baabou A, Bakri Y, Dakka N. Determination of phenol content and antibacterial activity of five medicinal plants ethanolic extracts from North-West of Morocco. J Plant PatholMicrobiol. 2016 Jun 22;7(342):2.
UNESCO. Culture and Health, Orientation Texts – World Decade for Cultural Development 1988 – 1997, Document CLT/DEC/PRO – 1996, Paris, France 19960.
Mahato SB, Sen S. Advances in triterpenoid research, 1990–1994. Phytochemistry. 1997 Apr 1;44(7):1185-236.https://www.sciencedirect.com/science/article/pii/S0031942296006395
Aliyu, A.B., Musa, A.M., Abdullahi, M.S.,Ibrahimi, H and Oyewale, A.O. Phytochemical screening and antibacterial activities of Vernoniaambigua, Vernoniablumeoides and Vernoniaoocephala (Asteraceae). Acta Polo. Pharm. 2011; 68(1): 67-73.
Ashish, A., Mohini, K. and Abhiram, R. Preparation and evaluation of polyherbal cosmetic cream. Scholars Res. Libr., 2013; 5(1): 83-88.
Barry, B.W.: Topical preparations. In: Pharmaceutics, The Science of Dosage Form Design. Ed.: Aulton ME. Churchill Livingstone, Edinburgh, International student edition, 1999; 381-411.
Builders, M.I., Wannang, N.N., Ajoku, G.A., Builders, P.F., Orisadipe, A and Aguiyi, J.C. Evaluation of the Antimalarial Potential of VernoniaambiguaKotchy and Peyr (Asteraceae). Int. J. Pharmacol., 2011; 7(2): 238- 247.
Chen, M.X., Alexander, K.S., and Baki, G. Formulation and Evaluation of Antibacterial Creams and Gels Containing Metal Ions for Topical Application. J. Pharm., 2016; Article ID 5754349, 10 pages.
Hossain, M.S., Hossain, M.M., Zaman, S., Mondal, M. and Rana, S. Phytochemical screening, antioxidant and antimicrobial activities of leaf extracts of Randiauliginosa. World J Pharm Sci, 2014; 2(12): 1687-1696.