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Assessment of knowledge, attitude and practice of pharmacovigilance and ADR reporting in health care professionals
Corresponding Author(s) : Anagha K.P
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 11 No. 4 (2023): 2023 Volume -11 - Issue 4
Abstract
Background: Lack of awareness among healthcare professionals is cited as one of the main reasons along with under reporting of adverse drug reactions. Knowledge, attitude, and practice (KAP) studies can help to understand various issues and improve pharmacovigilance system.
Objectives: The present study was undertaken to assess the knowledge, attitude, and practices (KAP) regarding pharmacovigilance and ADR reporting among healthcare professionals at the various departments of hospitals in Northern Kerala to get an insight into the causes of under-reporting of ADRs.
Materials and Methods: The data was collected using a pre-designed questionnaire. A total of 25multiple choice questions related to knowledge, attitude and practice. There were 6 Knowledge based 7 Attitude and 12 Practice based questions. The participants were graded in three categories as good, fair and poor depending on the mean score. The data were interpreted by calculating the frequencies, one-way ANOVA test.
Results: A total of 300 healthcare professionals who completed the questionnaire were considered of which 110 were doctors, 98 were nurses and 92were pharmacist. Among them, doctors have relatively better score than nurses and pharmacists in knowledge and attitude. Most healthcare professionals have showed fair practice in pharmacovigilance and ADR reporting and the pharmacists being the best performers.
Conclusion: To facilitate the culture of reporting and creating awareness among health professionals, CME, workshops, conferences, post training reminders such as periodic E-mails and SMS alerts should be conducted. Pharmacovigilance is being taught to some degree in theory, but the knowledge on the practical method is lacking. The existing academic curriculum can be amended to incorporate the application of pharmacovigilance in the medical practice.
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- Ganesan S, Sandhiya S, Reddy KC, Subrahmanyam DK, Adithan C. The impact of the educational intervention on knowledge, attitude, and practice of pharmacovigilance toward adverse drug reactions reporting among health-care professionals in a tertiary care hospital in South India. J Nat Sci Biol Med. 2017 Jul;8(2):203. doi: 10.4103/0976-9668.210014.
- Wangge G, Akbar W. Knowledge, attitudes and practice of pharmacovigilance among health care professionals in Indonesia. Health Sci J Indones. 2016;7(1):59-63. doi: 10.22435/hsji.v7i1.5285.59-63.
- Fornasier G, Francescon S, Leone R, Baldo P. An historical overview over pharmacovigilance. Int J Clin Pharm. 2018 Aug;40(4):744-7. doi: 10.1007/s11096-018-0657-1.
- Routledge P. 150 years of pharmacovigilance. Lancet. 1998 Apr 18;351(9110):1200-1. doi: 10.1016/S0140-6736(98)03148-1.
- Levy M. The epidemiological evaluation of major upper gastrointestinal bleeding in relation to aspirin use. In: Epidemiological concepts in clinical pharmacology. Berlin, Heidelberg: Springer Berlin Heidelberg; 1987. p. 100-4.
- Jeetu G, Anusha G. Pharmacovigilance: a worldwide master key for drug safety monitoring. J Young Pharm. 2010 Jul;2(3):315-20. doi: 10.4103/0975-1483.66802.
- Kulkarni RD. Reporting systems for rare side effects of nonnarcotic analgesics in India. Problems and opportunities. Med Toxicol. 1986;1;Suppl 1:110-3. PMID 3821424.
- Moride Y, Haramburu F, Requejo AA, Bégaud B. Under-reporting of adverse drug reactions in general practice. Br J Clin Pharmacol. 1997 Feb;43(2):177-81. doi: 10.1046/j.1365-2125.1997.05417.x.
- Adithan C. National pharmacovigilance programme. Indian J Pharmacol. 2005 Nov 1;37(6):347. doi: 10.4103/0253-7613.19069.
- Nissen T, Wynn R. The clinical case report: a review of its merits and limitations. BMC Res Notes. 2014 Dec;7(1):1-7.
- Sahu RK, Yadav R, Prasad P, Roy A, Chandrakar S. Adverse drug reactions monitoring: prospects and impending challenges for pharmacovigilance. Springerplus. 2014 Dec;3(1):1-9.
- Aggarwal V, Gupta SK, Sharma DK, Arya S, Singh S. Adverse drug reaction policy in a tertiary care hospital. Int J Res Found Hosp Healthc Admin. 2015;3(1):41-7. doi: 10.5005/jp-journals-10035-1035.
- Bepari A, Niazi SK, Rahman I, Dervesh AM. The comparative evaluation of knowledge, attitude, and practice of different health-care professionals about the pharmacovigilance system of India. J Adv Pharm Technol Res. 2019 Apr;10(2):68. doi: 10.4103/japtr.JAPTR_4_19.
- Ahmad A, Patel I, Balkrishnan R, Mohanta GP, Manna PK. An evaluation of knowledge, attitude and practice of Indian pharmacists towards adverse drug reaction reporting: A pilot study. Perspect Clin Res. 2013 Oct;4(4):204. doi: 10.4103/2229-3485.120168.
- Alsaleh FM, Alzaid SW, Abahussain EA, Bayoud T, Lemay J. Knowledge, attitude and practices of pharmacovigilance and adverse drug reaction reporting among pharmacists working in secondary and tertiary governmental hospitals in Kuwait. Saudi Pharm J. 2017 Sep 1;25(6):830-7. doi: 10.1016/j.jsps.2016.12.004.
References
Ganesan S, Sandhiya S, Reddy KC, Subrahmanyam DK, Adithan C. The impact of the educational intervention on knowledge, attitude, and practice of pharmacovigilance toward adverse drug reactions reporting among health-care professionals in a tertiary care hospital in South India. J Nat Sci Biol Med. 2017 Jul;8(2):203. doi: 10.4103/0976-9668.210014.
Wangge G, Akbar W. Knowledge, attitudes and practice of pharmacovigilance among health care professionals in Indonesia. Health Sci J Indones. 2016;7(1):59-63. doi: 10.22435/hsji.v7i1.5285.59-63.
Fornasier G, Francescon S, Leone R, Baldo P. An historical overview over pharmacovigilance. Int J Clin Pharm. 2018 Aug;40(4):744-7. doi: 10.1007/s11096-018-0657-1.
Routledge P. 150 years of pharmacovigilance. Lancet. 1998 Apr 18;351(9110):1200-1. doi: 10.1016/S0140-6736(98)03148-1.
Levy M. The epidemiological evaluation of major upper gastrointestinal bleeding in relation to aspirin use. In: Epidemiological concepts in clinical pharmacology. Berlin, Heidelberg: Springer Berlin Heidelberg; 1987. p. 100-4.
Jeetu G, Anusha G. Pharmacovigilance: a worldwide master key for drug safety monitoring. J Young Pharm. 2010 Jul;2(3):315-20. doi: 10.4103/0975-1483.66802.
Kulkarni RD. Reporting systems for rare side effects of nonnarcotic analgesics in India. Problems and opportunities. Med Toxicol. 1986;1;Suppl 1:110-3. PMID 3821424.
Moride Y, Haramburu F, Requejo AA, Bégaud B. Under-reporting of adverse drug reactions in general practice. Br J Clin Pharmacol. 1997 Feb;43(2):177-81. doi: 10.1046/j.1365-2125.1997.05417.x.
Adithan C. National pharmacovigilance programme. Indian J Pharmacol. 2005 Nov 1;37(6):347. doi: 10.4103/0253-7613.19069.
Nissen T, Wynn R. The clinical case report: a review of its merits and limitations. BMC Res Notes. 2014 Dec;7(1):1-7.
Sahu RK, Yadav R, Prasad P, Roy A, Chandrakar S. Adverse drug reactions monitoring: prospects and impending challenges for pharmacovigilance. Springerplus. 2014 Dec;3(1):1-9.
Aggarwal V, Gupta SK, Sharma DK, Arya S, Singh S. Adverse drug reaction policy in a tertiary care hospital. Int J Res Found Hosp Healthc Admin. 2015;3(1):41-7. doi: 10.5005/jp-journals-10035-1035.
Bepari A, Niazi SK, Rahman I, Dervesh AM. The comparative evaluation of knowledge, attitude, and practice of different health-care professionals about the pharmacovigilance system of India. J Adv Pharm Technol Res. 2019 Apr;10(2):68. doi: 10.4103/japtr.JAPTR_4_19.
Ahmad A, Patel I, Balkrishnan R, Mohanta GP, Manna PK. An evaluation of knowledge, attitude and practice of Indian pharmacists towards adverse drug reaction reporting: A pilot study. Perspect Clin Res. 2013 Oct;4(4):204. doi: 10.4103/2229-3485.120168.
Alsaleh FM, Alzaid SW, Abahussain EA, Bayoud T, Lemay J. Knowledge, attitude and practices of pharmacovigilance and adverse drug reaction reporting among pharmacists working in secondary and tertiary governmental hospitals in Kuwait. Saudi Pharm J. 2017 Sep 1;25(6):830-7. doi: 10.1016/j.jsps.2016.12.004.