Case report on generalized bullous recurrent fixed drug eruption caused by co-trimoxazole
Corresponding Author(s) : Sowmya.Nadendla
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 3 No. 1 (2015): 2015 Volume 3- Issue -1
Abstract
Fixed drug eruption is a allergic reaction to particular medicine.This is case of 65-year-old male patient with complaints of multiple discrete dusty macules over hands, legs and feet and various other areas associated with burning sensation with history of similar complaints in the past two to three times & on enquiry patient was prescribed co-trimoxazole by a local practitioner without taking adequate medication history. Cotrimoxazole was suspected as the offending drug in causing fixed drug eruption in this case and its role was confirmed by patch test. According to WHO-UMC & Naranjo assessment scales this adverse effect comes under possible adverse effect.
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[1] Sánchez Morillas L, Laguna Martínez JJ, Rea no Martos M, Gómez Tembleque P, Rojo Andrés E. Fixed drug eruption caused by amoxicillin-clavulanic acid. Ann Allergy Asthma, 101, 2008, 335.
[2] Nibedita Patro, Maitreyee Panda,Monalisa Jena, Swati Mishra; Multifocal Fixed Drug Eruptions: A Case Series Int. J. Pharm. Sci. Rev. Res., 23(1), Nov -Dec 2013; n13, 63-66
[3] S.C. Bharija,*and M.S. Belhaj Fixed Drug Eruption Due To Cotrimoxazole Australasian Journal of Dermatology 30(1) ,April 1989 ,Pg 43–44.
[4] Barbaud A, Reichert-Penetrat S, Trechot P, Jacquin Petit MA, Ehlinger A, Noirez V, et al. The use of skin testing in investigation of adverse cutaneous drug reactions. Br J Dermatol, 149, 1998, 139.
[5] BC Dwari, S Bajracharya, S Gupta, P Mishra, S Palaian, K Alam, S Prabhu, M Prabhu ; Fixed drug eruption due to co-trimoxazole: Journal of Institute of Medicine ;Vol 28, No 2 (2006)
[6] Lin TK, Hsu MM, Lee JY. Clinical resemblance of widespread bullous fixed drug eruption to Stevens-Johnson syndrome or toxic epidermal necrolysis: report of two cases. J Formos Med Assoc. 2002 Aug;101(8):572-6.
[7] Mizukawa Y, Shiohara T, Fixed drug eruption: a prototypic disorder mediated by effector memory T cells, Curr Allergy Asthma Rep, 9(1), 2009, 71-77.
[8] Benomar S, Ismaili N, Koufane J, Senouci K, Hassam B. [Fixed food eruption caused by liquorice.]. Ann Dermatol Venereol. Feb 2010;137(2):121-123.
References
[2] Nibedita Patro, Maitreyee Panda,Monalisa Jena, Swati Mishra; Multifocal Fixed Drug Eruptions: A Case Series Int. J. Pharm. Sci. Rev. Res., 23(1), Nov -Dec 2013; n13, 63-66
[3] S.C. Bharija,*and M.S. Belhaj Fixed Drug Eruption Due To Cotrimoxazole Australasian Journal of Dermatology 30(1) ,April 1989 ,Pg 43–44.
[4] Barbaud A, Reichert-Penetrat S, Trechot P, Jacquin Petit MA, Ehlinger A, Noirez V, et al. The use of skin testing in investigation of adverse cutaneous drug reactions. Br J Dermatol, 149, 1998, 139.
[5] BC Dwari, S Bajracharya, S Gupta, P Mishra, S Palaian, K Alam, S Prabhu, M Prabhu ; Fixed drug eruption due to co-trimoxazole: Journal of Institute of Medicine ;Vol 28, No 2 (2006)
[6] Lin TK, Hsu MM, Lee JY. Clinical resemblance of widespread bullous fixed drug eruption to Stevens-Johnson syndrome or toxic epidermal necrolysis: report of two cases. J Formos Med Assoc. 2002 Aug;101(8):572-6.
[7] Mizukawa Y, Shiohara T, Fixed drug eruption: a prototypic disorder mediated by effector memory T cells, Curr Allergy Asthma Rep, 9(1), 2009, 71-77.
[8] Benomar S, Ismaili N, Koufane J, Senouci K, Hassam B. [Fixed food eruption caused by liquorice.]. Ann Dermatol Venereol. Feb 2010;137(2):121-123.