Effect of Age and Stage on Quality of Life (Physical Health) in 3D-CRT Radiotherapy for Breast Cancer at the Hasanuddin University Hospital Radiotherapy Installation
Corresponding Author(s) : Nitia Putri Maulana
tiaputrim23@gmail.com
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 10 No. 4 (2022): 2022 Volume -10 - Issue 4
Abstract
Breast cancer is the highest malignancy in women among other types of cancer and includes a very diverse disease. Radiation therapy aims to deliver the minimum possible dose to healthy tissue and to the maximum possible dose of cancer cells. Measuring quality of life in breast cancer patients is very important to assess treatment outcomes which are closely related to age and stage. The 3D-CRT technique causes toxic side effects on the skin and in another study the results of breast cancer treatment using the 3D-CRT technique resulted in a worse patient's quality of life than the IMRT technique. However, breast cancer radiation therapy at the Hasanuddin University Hospital Radiotherapy Installation in Makassar still uses the 3D-CRT technique. This study uses a quantitative descriptive research with a cross sectional study approach. 80% of breast cancer patients who have undergone radiation therapy have a poor quality of life (physical health) and 20% have a good quality of life (physical health). There is a significant relationship between age and quality of life (physical health) because the value of Sig. (2-tailed) of 0.004 and there is a significant relationship between stage and quality of life (physical health) with Sig. (2-tailed) of 0.022.
Keywords
Radiotherapy, 3D-CRT, Breast Cancer, Quality of Life
1.
Nitia Putri Maulana, I Putu Eka Juliantara, I Wayan Juliasa, Ngakan Putu Daksa Genapati. Effect of Age and Stage on Quality of Life (Physical Health) in 3D-CRT Radiotherapy for Breast Cancer at the Hasanuddin University Hospital Radiotherapy Installation. Int. J. of Allied Med. Sci. and Clin. Res. [Internet]. 2023 Jan. 12 [cited 2025 Sep. 21];10(4):499-505. Available from: https://ijamscr.com/ijamscr/article/view/1279
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References
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1. Anjum F, Razvi N, Masood MA. Breast cancer therapy: A mini review. MOJDDT. 2017 May 16;1(2). doi: 10.15406/mojddt.2017.01.00006.
2. World Health Organization. Breast cancer research for cancer prevention. Questions and Answers. International Agency for Research on Cancer; 2020. p. 5.
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8. Bull FC, Al-Ansari SS, Biddle S, Borodulin K, Buman MP, Cardon G, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med. 2020 Dec;54(24):1451-62. doi: 10.1136/bjsports-2020-102955, PMID 33239350.
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11. Park BW, Lee S, Lee AR, Lee KH, Hwang SY. Quality of life differences between younger and older breast cancer patients. J Breast Cancer. 2011;14(2):112-8. doi: 10.4048/jbc.2011.14.2.112, PMID 21847405.
12. Chalubinska-Fendler J, Butwicka A, Ka?mierczak P, Ja?ocha-Kaczka A, Fendler W, Fijuth J. Determinants of quality of life in patients with breast cancer undergoing external beam radiotherapy. aoms. 2015;6:136.
13. Chen HL, Zhou MQ, Tian W, Meng KX, He HFEffect of Age on Breast Cancer Patient Prognoses: a Population-Based Study Using the SEER 18 Database. PLOS ONE. 2016 Oct 31;11(10):e0165409. doi: 10.1371/journal.pone.0165409, PMID 27798652.
14. Park BW, Lee S, Lee AR, Lee KH, Hwang SY. Quality of life differences between younger and older breast cancer patients. J Breast Cancer. 2011;14(2):112-8. doi: 10.4048/jbc.2011.14.2.112, PMID 21847405.
15. Sio TT, Chang K, Jayakrishnan R, Wu D, Politi M, Malacarne D, et al. Patient age is related to decision-making, treatment selection, and perceived quality of life in breast cancer survivors. World J Surg Oncol. 2014;12(1):230. doi: 10.1186/1477-7819-12-230, PMID 25052797.
References
1. Anjum F, Razvi N, Masood MA. Breast cancer therapy: A mini review. MOJDDT. 2017 May 16;1(2). doi: 10.15406/mojddt.2017.01.00006.
2. World Health Organization. Breast cancer research for cancer prevention. Questions and Answers. International Agency for Research on Cancer; 2020. p. 5.
3. Balaji K, Subramanian B, Yadav P, Anu Radha C, Ramasubramanian V. Radiation therapy for breast cancer: literature review. Med Dosim. 2016;41(3):253-7. doi: 10.1016/j.meddos.2016.06.005, PMID 27545009.
4. Abu-Gheida IH. Introduction to radiotherapy. 2016 [cited Jun 4 2022]. Available from: http://rgdoi.net/10.13140/RG.2.1.4729.8160.
5. Gianfaldoni S, Gianfaldoni R, Wollina U, Lotti J, Tchernev G, Lotti T. An overview on radiotherapy: from its history to its current applications in dermatology. Open Access Maced J Med Sci. 2017 Jul 18;5(4):521-5. doi: 10.3889/oamjms.2017.122, PMID 28785349.
6. Podgorsak EB. Special procedures and techniques in radiotherapy. Vol. 44.
7. Beyzadeoglu M, Ozyigit G, Ebruli C. Basic radiation oncology [internet]. Springer International Publishing; 2022. Available from: https://books.google.co.id/books?id=/_2VXEAAAQBAJ.
8. Bull FC, Al-Ansari SS, Biddle S, Borodulin K, Buman MP, Cardon G, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med. 2020 Dec;54(24):1451-62. doi: 10.1136/bjsports-2020-102955, PMID 33239350.
9. Post MW. Definitions of quality of life: what has happened and how to move on. Top Spinal Cord Inj Rehabil. 2014 Jul;20(3):167-80. doi: 10.1310/sci2003-167, PMID 25484563.
10. Kurniawan A, Lugito NPH, Susanti S, Tjiang MM, Yanto TA, Wijaya I, et al. Health related quality of life focus on physical and mental health in breast cancer patients: Preliminary Study [preliminary study]. Ann Oncol. 2014 Oct;25:v103. doi: 10.1093/annonc/mdu436.126.
11. Park BW, Lee S, Lee AR, Lee KH, Hwang SY. Quality of life differences between younger and older breast cancer patients. J Breast Cancer. 2011;14(2):112-8. doi: 10.4048/jbc.2011.14.2.112, PMID 21847405.
12. Chalubinska-Fendler J, Butwicka A, Ka?mierczak P, Ja?ocha-Kaczka A, Fendler W, Fijuth J. Determinants of quality of life in patients with breast cancer undergoing external beam radiotherapy. aoms. 2015;6:136.
13. Chen HL, Zhou MQ, Tian W, Meng KX, He HFEffect of Age on Breast Cancer Patient Prognoses: a Population-Based Study Using the SEER 18 Database. PLOS ONE. 2016 Oct 31;11(10):e0165409. doi: 10.1371/journal.pone.0165409, PMID 27798652.
14. Park BW, Lee S, Lee AR, Lee KH, Hwang SY. Quality of life differences between younger and older breast cancer patients. J Breast Cancer. 2011;14(2):112-8. doi: 10.4048/jbc.2011.14.2.112, PMID 21847405.
15. Sio TT, Chang K, Jayakrishnan R, Wu D, Politi M, Malacarne D, et al. Patient age is related to decision-making, treatment selection, and perceived quality of life in breast cancer survivors. World J Surg Oncol. 2014;12(1):230. doi: 10.1186/1477-7819-12-230, PMID 25052797.
2. World Health Organization. Breast cancer research for cancer prevention. Questions and Answers. International Agency for Research on Cancer; 2020. p. 5.
3. Balaji K, Subramanian B, Yadav P, Anu Radha C, Ramasubramanian V. Radiation therapy for breast cancer: literature review. Med Dosim. 2016;41(3):253-7. doi: 10.1016/j.meddos.2016.06.005, PMID 27545009.
4. Abu-Gheida IH. Introduction to radiotherapy. 2016 [cited Jun 4 2022]. Available from: http://rgdoi.net/10.13140/RG.2.1.4729.8160.
5. Gianfaldoni S, Gianfaldoni R, Wollina U, Lotti J, Tchernev G, Lotti T. An overview on radiotherapy: from its history to its current applications in dermatology. Open Access Maced J Med Sci. 2017 Jul 18;5(4):521-5. doi: 10.3889/oamjms.2017.122, PMID 28785349.
6. Podgorsak EB. Special procedures and techniques in radiotherapy. Vol. 44.
7. Beyzadeoglu M, Ozyigit G, Ebruli C. Basic radiation oncology [internet]. Springer International Publishing; 2022. Available from: https://books.google.co.id/books?id=/_2VXEAAAQBAJ.
8. Bull FC, Al-Ansari SS, Biddle S, Borodulin K, Buman MP, Cardon G, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med. 2020 Dec;54(24):1451-62. doi: 10.1136/bjsports-2020-102955, PMID 33239350.
9. Post MW. Definitions of quality of life: what has happened and how to move on. Top Spinal Cord Inj Rehabil. 2014 Jul;20(3):167-80. doi: 10.1310/sci2003-167, PMID 25484563.
10. Kurniawan A, Lugito NPH, Susanti S, Tjiang MM, Yanto TA, Wijaya I, et al. Health related quality of life focus on physical and mental health in breast cancer patients: Preliminary Study [preliminary study]. Ann Oncol. 2014 Oct;25:v103. doi: 10.1093/annonc/mdu436.126.
11. Park BW, Lee S, Lee AR, Lee KH, Hwang SY. Quality of life differences between younger and older breast cancer patients. J Breast Cancer. 2011;14(2):112-8. doi: 10.4048/jbc.2011.14.2.112, PMID 21847405.
12. Chalubinska-Fendler J, Butwicka A, Ka?mierczak P, Ja?ocha-Kaczka A, Fendler W, Fijuth J. Determinants of quality of life in patients with breast cancer undergoing external beam radiotherapy. aoms. 2015;6:136.
13. Chen HL, Zhou MQ, Tian W, Meng KX, He HFEffect of Age on Breast Cancer Patient Prognoses: a Population-Based Study Using the SEER 18 Database. PLOS ONE. 2016 Oct 31;11(10):e0165409. doi: 10.1371/journal.pone.0165409, PMID 27798652.
14. Park BW, Lee S, Lee AR, Lee KH, Hwang SY. Quality of life differences between younger and older breast cancer patients. J Breast Cancer. 2011;14(2):112-8. doi: 10.4048/jbc.2011.14.2.112, PMID 21847405.
15. Sio TT, Chang K, Jayakrishnan R, Wu D, Politi M, Malacarne D, et al. Patient age is related to decision-making, treatment selection, and perceived quality of life in breast cancer survivors. World J Surg Oncol. 2014;12(1):230. doi: 10.1186/1477-7819-12-230, PMID 25052797.