Date Log
Submitted
December 21, 2022
Published
December 29, 2022
Potential of Kidney Bean Extract (Phaseolus Vulgaris L) in the Management of Anemia in Pregnant Women
Corresponding Author(s) : Anggun Sasmita Anggun
anggnsasmita@gmail.com
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 10 No. 4 (2022): 2022 Volume -10 - Issue 4
Abstract
ABSTRACT
Background: Anemia occurs when there is a decrease in the volume of blood cells, thereby reducing the level of oxygen available to vital organs. In anemia, the hemoglobin level in the body is below 11 gr/dl. It is estimated that 42.8% of mothers in this country suffer from anemia during pregnancy, according to WHO. The plasma volume is higher and the number of red blood cells (erythrocytes) is higher, causing the blood to thin and the concentration of hemoglobin (Hb) to decrease.
Research objectives: To analyzedifferences in hemoglobin levels and the number of erythrocytes in pregnant women with anemia before and after administration of red bean extract (phaseolus vulgaris l) compared to the control group (fe tablets).
Method: Quasy experimentwith pretest-posttest design with control group design. The sample consisted of 40 pregnant women with anemia which were divided into 2 groups, namely 20 intervention groups and 20 control groups.
Results: The analysis showed red bean extract combined with Fe given to pregnant womenevery day for 14 days can significantly increase hemoglobin levels with an average increase in the intervention group increasing 11.515 gr/dl while in the control group increasing 11.960 gr/dl. While the results of the analysisThe number of erythrocytes in the intervention group increased 4.3200 million/cell and in the control group increased 3.9640 million/cell.
Conclusion: Red bean extract (phaseolus vulgaris l) has the potential to increase hemoglobin levels and erythrocyte counts in anemic pregnant women compared to the control group.
Keywords: red bean extract; Pregnant mother; anemia (Hb levels, red blood cells)
Background: Anemia occurs when there is a decrease in the volume of blood cells, thereby reducing the level of oxygen available to vital organs. In anemia, the hemoglobin level in the body is below 11 gr/dl. It is estimated that 42.8% of mothers in this country suffer from anemia during pregnancy, according to WHO. The plasma volume is higher and the number of red blood cells (erythrocytes) is higher, causing the blood to thin and the concentration of hemoglobin (Hb) to decrease.
Research objectives: To analyzedifferences in hemoglobin levels and the number of erythrocytes in pregnant women with anemia before and after administration of red bean extract (phaseolus vulgaris l) compared to the control group (fe tablets).
Method: Quasy experimentwith pretest-posttest design with control group design. The sample consisted of 40 pregnant women with anemia which were divided into 2 groups, namely 20 intervention groups and 20 control groups.
Results: The analysis showed red bean extract combined with Fe given to pregnant womenevery day for 14 days can significantly increase hemoglobin levels with an average increase in the intervention group increasing 11.515 gr/dl while in the control group increasing 11.960 gr/dl. While the results of the analysisThe number of erythrocytes in the intervention group increased 4.3200 million/cell and in the control group increased 3.9640 million/cell.
Conclusion: Red bean extract (phaseolus vulgaris l) has the potential to increase hemoglobin levels and erythrocyte counts in anemic pregnant women compared to the control group.
Keywords: red bean extract; Pregnant mother; anemia (Hb levels, red blood cells)
Keywords
red bean extract; Pregnant mother; anemia (Hb levels, red blood cells)
Anggun, A. S., Runjati, & Arwani. (2022). Potential of Kidney Bean Extract (Phaseolus Vulgaris L) in the Management of Anemia in Pregnant Women. International Journal of Allied Medical Sciences and Clinical Research, 10(4), 477–482. https://doi.org/10.61096/ijamscr.v10.iss4.2022.477-482
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References
-
1. Achebe MM, Gafter-Gvili A. How I treat anemia in pregnancy: Iron, cobalamin, and folate. Blood. 2017;129(8):940-949. doi:10.1182/blood-2016-08-672246
2. Organization WH. WHO recommendations on antenatal care for a positive pregnancy experience. World Heal Organ. Published online 2016. https://www.who.int/publications/i/item/9789241549912
3. Tunkyi K, Moodley J. Anemia and pregnancy outcomes: a longitudinal study. J Matern Neonatal Med. 2018;31(19):2594-2598. doi:10.1080/14767058.2017.1349746
4. Adam I, Ibrahim Y, Elhardello O. Prevalence, types and determinants of anemia among pregnant women in Sudan: A systematic review and meta-analysis. BMC Hematol. 2018;18(1):4-11. doi:10.1186/s12878-018-0124-1
5. Kemenkes RI. Profil Kesehatan Indonesia.; 2019. https://pusdatin.kemkes.go.id/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-indonesia-2019.pdf
6. Kemenkes RI. Data dan Informasi Profil Kesehatan Indonesia. J Chem Inf. 2018;53(9):1689-1699. https://pusdatin.kemkes.go.id/resources/download/pusdatin/profil-kesehatan-indonesia/Data-dan-Informasi_Profil-Kesehatan-Indonesia-2018.pdf
7. Dinkes Kota Kendari. Narasi Profil Kesehatan 2019. Profil Kesehat Kota Kendari. Published online 2019:1-47.
8. Dinkes. Dinas Kesehatan Kota Kendari (Rekapan Data Gizi Dan Rekapitulasi Ibu Hamil Anemia 2017-2019).; 2019.
9. Kemenkes RI. Hasil Riset Kesehatan Dasar Tahun 2018. Kementrian Kesehat RI. 2018;53(9):1689-1699. https://kesmas.kemkes.go.id/assets/upload/dir_519d41d8cd98f00/files/Hasil-riskesdas-2018_1274.pdf
10. Lepo-lepo P. Profil Puskesmas Lepo-Lepo.; 2019.
11. Lepo-lepo P. Profil Puskesmas Lepo-Lepo.; 2020.
12. Lepo-lepo P. Profil Puskesmas Lepo-Lepo.; 2021.
13. Rahman MM, Ngadan DP, Arif MT. Factors affecting satisfaction on antenatal care services in Sarawak, Malaysia: evidence from a cross sectional study. Springerplus. 2016;5(1). doi:10.1186/s40064-016-2447-3
14. Kemenkes RI. Profil Kesehatan Indonesia. In: Jakarta. ; 2020. https://www.kemkes.go.id/downloads/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-Indonesia-Tahun-2020.pdf
15. Umami R, Rasipin, Jati SP. The Effect of Red Bean Powder ( Phaseolus vulgaris L .) as Adjuvant Therapy on the Blood Profile of Anemic White Rats. Int J Multidiscip Educ Res. 2020;5(2):1-6. http://www.educationjournal.in/archives/2020/vol5/issue2/5-1-25
16. Umrah A St. Pengaruh Konsumsi Kacang Merah Terhadap Pengobatan Anemia Pada Ibu Hamil Di Puskesmas Sendana Kota Palopo. J voice midwifery. 2018;08(01):688-695. https://www.journal.umpalopo.ac.id/index.php/VoM/article/view/3
17. Murtini G. Farmasetika Dasar. Kemenkes RI. Published online 2016:168. http://bppsdmk.kemkes.go.id/pusdiksdmk/wp-content/uploads/2017/08/Farmestika-Komprehensif.pdf
18. Pratiwi Cahya Skania, Djaswadi Dasuki FSU. The Effect Of Fe Tablet Consumption On Hemoglobin (Hb) Increase In Pregnant Women: A Systematic Literature Review. Midwiferia J Kebidanan. 2021;7(1):8-13. doi:oi: 10.21070/midwiferia.v%vi%i.568
19. Uluwiyatun U, Runjati R, Suwondo A. Pengaruh Konsumsi Rumput Laut (Eucheuma Sp) terhadap Peningkatan Kadar Hemoglobin dan Status Fe Ibu Hamil Anemia di Kabupaten Pekalongan. J Kebidanan. 2015;3(7):8-15. doi:https://doi.org/10.31983/jkb.v3i7.117
20. Petry N, Boy E, Wirth JP, Hurrell RF. Review: The potential of the common bean (phaseolus vulgaris) as a vehicle for iron biofortification. Nutrients. 2015;7(2):1144-1173. doi:10.3390/nu7021144
21. Wahyuni C, Natalia S, Rohmah M, et al. The effct consumtion of red beans (Phaseolus VulgarisL) boiled on hemoglob in levelsin adolescent in institute of health science strada Indonesia. Eur J Mol Clin Med. 2020;7(2):4753-4759. https://ejmcm.com/article_3058.html
22. Mana TA et all. Peningkatan nilai hemoglobin, MCV, MCH, dan feritin pada kasus anemia defisiensi besi dengan ramuan jamu di klinik Saintifikasi Jamu Hortus Medicus. Media Gizi Mikro Indones. 2017;8(2):127-26. doi:https://doi.org/10.22435/mgmi.v8i2.604
23. Susiloningtyas I. Pemberian zat besi (Fe) dalam Kehamilan. Maj Ilm Sultan Agung. 2019;20(128):73-99.
24. Butar Butar, Gabriella Jasmine D. Penngaruh Pemberian Jus Kacang Merah Soya terhadap kadar hemoglobin pada remaja putri. Semant Sch. Published online 2020. doi:https://www.semanticscholar.org/paper/Pengaruh-Pemberian-Jus-Kacang-Merah-Soya-terhadap-Butar-Par’i/5935702da5b8ac362183353e7129d8c4b8098ee4
25. Hariya Fitri F, Susilowati D, Kurniarum A. Pengaruh Konsumsi Jus Kacang Merah (Phaseolus Vulgaris) Terhadap Kadar Hemoglobin Remaja Putri Di Pondok Pesantren Nurul Quran Kecamatan Kokap Kabupaten Kulon Progo Provinsi Daerah Istimewa Yogyakarta. J Midwifery Sci Women’s Heal. 2022;2(2):60-66. doi:10.36082/jmswh.v2i2.513
26. Aliviameita A, Puspitasari. Buku Ajar Hematologi.; 2019. doi:https://doi.org/10.21070/2019/978-623-7578-00-0
27. Arwani, Hardhono Susanto, Dian Ratna Sawitri AR, Khristophorus Heri Nugroho Hario Seno, Bagoes Widjanarko EE. The Influence of Family-Centered Nursing and Spiritual Therapies on Self-Management and Glycated Hemoglobin A. J Int Dent Med Res. 2018;11(3):1636-1639. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067013194&partnerID=40&md5=3ecc16194d87f2064958f5a3c125c939
28. Arianti M. Potensi senyawa antioksidan alami pada berbagai jenis kacang. Ilmu Gizi Indones. 2018;1(2):134-143. doi:https://doi.org/10.35842/ilgi.v1i2.7
29. Rodríguez L, Mendez D, Montecino H, et al. Role of Phaseolus vulgaris L. in the Prevention of Cardiovascular Diseases-Cardioprotective Potential of Bioactive Compounds. J Akad. 2022;11(2). doi:10.3390/plants11020186
30. Qin G, Wang F, Liang H, et al. Subchronic Study of a White Kidney Bean (Phaseolus vulgaris) Extract with ? -Amylase Inhibitory Activity. Biomed Res Int. 2019;2019. doi:10.1155/2019/9272345
References
1. Achebe MM, Gafter-Gvili A. How I treat anemia in pregnancy: Iron, cobalamin, and folate. Blood. 2017;129(8):940-949. doi:10.1182/blood-2016-08-672246
2. Organization WH. WHO recommendations on antenatal care for a positive pregnancy experience. World Heal Organ. Published online 2016. https://www.who.int/publications/i/item/9789241549912
3. Tunkyi K, Moodley J. Anemia and pregnancy outcomes: a longitudinal study. J Matern Neonatal Med. 2018;31(19):2594-2598. doi:10.1080/14767058.2017.1349746
4. Adam I, Ibrahim Y, Elhardello O. Prevalence, types and determinants of anemia among pregnant women in Sudan: A systematic review and meta-analysis. BMC Hematol. 2018;18(1):4-11. doi:10.1186/s12878-018-0124-1
5. Kemenkes RI. Profil Kesehatan Indonesia.; 2019. https://pusdatin.kemkes.go.id/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-indonesia-2019.pdf
6. Kemenkes RI. Data dan Informasi Profil Kesehatan Indonesia. J Chem Inf. 2018;53(9):1689-1699. https://pusdatin.kemkes.go.id/resources/download/pusdatin/profil-kesehatan-indonesia/Data-dan-Informasi_Profil-Kesehatan-Indonesia-2018.pdf
7. Dinkes Kota Kendari. Narasi Profil Kesehatan 2019. Profil Kesehat Kota Kendari. Published online 2019:1-47.
8. Dinkes. Dinas Kesehatan Kota Kendari (Rekapan Data Gizi Dan Rekapitulasi Ibu Hamil Anemia 2017-2019).; 2019.
9. Kemenkes RI. Hasil Riset Kesehatan Dasar Tahun 2018. Kementrian Kesehat RI. 2018;53(9):1689-1699. https://kesmas.kemkes.go.id/assets/upload/dir_519d41d8cd98f00/files/Hasil-riskesdas-2018_1274.pdf
10. Lepo-lepo P. Profil Puskesmas Lepo-Lepo.; 2019.
11. Lepo-lepo P. Profil Puskesmas Lepo-Lepo.; 2020.
12. Lepo-lepo P. Profil Puskesmas Lepo-Lepo.; 2021.
13. Rahman MM, Ngadan DP, Arif MT. Factors affecting satisfaction on antenatal care services in Sarawak, Malaysia: evidence from a cross sectional study. Springerplus. 2016;5(1). doi:10.1186/s40064-016-2447-3
14. Kemenkes RI. Profil Kesehatan Indonesia. In: Jakarta. ; 2020. https://www.kemkes.go.id/downloads/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-Indonesia-Tahun-2020.pdf
15. Umami R, Rasipin, Jati SP. The Effect of Red Bean Powder ( Phaseolus vulgaris L .) as Adjuvant Therapy on the Blood Profile of Anemic White Rats. Int J Multidiscip Educ Res. 2020;5(2):1-6. http://www.educationjournal.in/archives/2020/vol5/issue2/5-1-25
16. Umrah A St. Pengaruh Konsumsi Kacang Merah Terhadap Pengobatan Anemia Pada Ibu Hamil Di Puskesmas Sendana Kota Palopo. J voice midwifery. 2018;08(01):688-695. https://www.journal.umpalopo.ac.id/index.php/VoM/article/view/3
17. Murtini G. Farmasetika Dasar. Kemenkes RI. Published online 2016:168. http://bppsdmk.kemkes.go.id/pusdiksdmk/wp-content/uploads/2017/08/Farmestika-Komprehensif.pdf
18. Pratiwi Cahya Skania, Djaswadi Dasuki FSU. The Effect Of Fe Tablet Consumption On Hemoglobin (Hb) Increase In Pregnant Women: A Systematic Literature Review. Midwiferia J Kebidanan. 2021;7(1):8-13. doi:oi: 10.21070/midwiferia.v%vi%i.568
19. Uluwiyatun U, Runjati R, Suwondo A. Pengaruh Konsumsi Rumput Laut (Eucheuma Sp) terhadap Peningkatan Kadar Hemoglobin dan Status Fe Ibu Hamil Anemia di Kabupaten Pekalongan. J Kebidanan. 2015;3(7):8-15. doi:https://doi.org/10.31983/jkb.v3i7.117
20. Petry N, Boy E, Wirth JP, Hurrell RF. Review: The potential of the common bean (phaseolus vulgaris) as a vehicle for iron biofortification. Nutrients. 2015;7(2):1144-1173. doi:10.3390/nu7021144
21. Wahyuni C, Natalia S, Rohmah M, et al. The effct consumtion of red beans (Phaseolus VulgarisL) boiled on hemoglob in levelsin adolescent in institute of health science strada Indonesia. Eur J Mol Clin Med. 2020;7(2):4753-4759. https://ejmcm.com/article_3058.html
22. Mana TA et all. Peningkatan nilai hemoglobin, MCV, MCH, dan feritin pada kasus anemia defisiensi besi dengan ramuan jamu di klinik Saintifikasi Jamu Hortus Medicus. Media Gizi Mikro Indones. 2017;8(2):127-26. doi:https://doi.org/10.22435/mgmi.v8i2.604
23. Susiloningtyas I. Pemberian zat besi (Fe) dalam Kehamilan. Maj Ilm Sultan Agung. 2019;20(128):73-99.
24. Butar Butar, Gabriella Jasmine D. Penngaruh Pemberian Jus Kacang Merah Soya terhadap kadar hemoglobin pada remaja putri. Semant Sch. Published online 2020. doi:https://www.semanticscholar.org/paper/Pengaruh-Pemberian-Jus-Kacang-Merah-Soya-terhadap-Butar-Par’i/5935702da5b8ac362183353e7129d8c4b8098ee4
25. Hariya Fitri F, Susilowati D, Kurniarum A. Pengaruh Konsumsi Jus Kacang Merah (Phaseolus Vulgaris) Terhadap Kadar Hemoglobin Remaja Putri Di Pondok Pesantren Nurul Quran Kecamatan Kokap Kabupaten Kulon Progo Provinsi Daerah Istimewa Yogyakarta. J Midwifery Sci Women’s Heal. 2022;2(2):60-66. doi:10.36082/jmswh.v2i2.513
26. Aliviameita A, Puspitasari. Buku Ajar Hematologi.; 2019. doi:https://doi.org/10.21070/2019/978-623-7578-00-0
27. Arwani, Hardhono Susanto, Dian Ratna Sawitri AR, Khristophorus Heri Nugroho Hario Seno, Bagoes Widjanarko EE. The Influence of Family-Centered Nursing and Spiritual Therapies on Self-Management and Glycated Hemoglobin A. J Int Dent Med Res. 2018;11(3):1636-1639. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067013194&partnerID=40&md5=3ecc16194d87f2064958f5a3c125c939
28. Arianti M. Potensi senyawa antioksidan alami pada berbagai jenis kacang. Ilmu Gizi Indones. 2018;1(2):134-143. doi:https://doi.org/10.35842/ilgi.v1i2.7
29. Rodríguez L, Mendez D, Montecino H, et al. Role of Phaseolus vulgaris L. in the Prevention of Cardiovascular Diseases-Cardioprotective Potential of Bioactive Compounds. J Akad. 2022;11(2). doi:10.3390/plants11020186
30. Qin G, Wang F, Liang H, et al. Subchronic Study of a White Kidney Bean (Phaseolus vulgaris) Extract with ? -Amylase Inhibitory Activity. Biomed Res Int. 2019;2019. doi:10.1155/2019/9272345
2. Organization WH. WHO recommendations on antenatal care for a positive pregnancy experience. World Heal Organ. Published online 2016. https://www.who.int/publications/i/item/9789241549912
3. Tunkyi K, Moodley J. Anemia and pregnancy outcomes: a longitudinal study. J Matern Neonatal Med. 2018;31(19):2594-2598. doi:10.1080/14767058.2017.1349746
4. Adam I, Ibrahim Y, Elhardello O. Prevalence, types and determinants of anemia among pregnant women in Sudan: A systematic review and meta-analysis. BMC Hematol. 2018;18(1):4-11. doi:10.1186/s12878-018-0124-1
5. Kemenkes RI. Profil Kesehatan Indonesia.; 2019. https://pusdatin.kemkes.go.id/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-indonesia-2019.pdf
6. Kemenkes RI. Data dan Informasi Profil Kesehatan Indonesia. J Chem Inf. 2018;53(9):1689-1699. https://pusdatin.kemkes.go.id/resources/download/pusdatin/profil-kesehatan-indonesia/Data-dan-Informasi_Profil-Kesehatan-Indonesia-2018.pdf
7. Dinkes Kota Kendari. Narasi Profil Kesehatan 2019. Profil Kesehat Kota Kendari. Published online 2019:1-47.
8. Dinkes. Dinas Kesehatan Kota Kendari (Rekapan Data Gizi Dan Rekapitulasi Ibu Hamil Anemia 2017-2019).; 2019.
9. Kemenkes RI. Hasil Riset Kesehatan Dasar Tahun 2018. Kementrian Kesehat RI. 2018;53(9):1689-1699. https://kesmas.kemkes.go.id/assets/upload/dir_519d41d8cd98f00/files/Hasil-riskesdas-2018_1274.pdf
10. Lepo-lepo P. Profil Puskesmas Lepo-Lepo.; 2019.
11. Lepo-lepo P. Profil Puskesmas Lepo-Lepo.; 2020.
12. Lepo-lepo P. Profil Puskesmas Lepo-Lepo.; 2021.
13. Rahman MM, Ngadan DP, Arif MT. Factors affecting satisfaction on antenatal care services in Sarawak, Malaysia: evidence from a cross sectional study. Springerplus. 2016;5(1). doi:10.1186/s40064-016-2447-3
14. Kemenkes RI. Profil Kesehatan Indonesia. In: Jakarta. ; 2020. https://www.kemkes.go.id/downloads/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-Indonesia-Tahun-2020.pdf
15. Umami R, Rasipin, Jati SP. The Effect of Red Bean Powder ( Phaseolus vulgaris L .) as Adjuvant Therapy on the Blood Profile of Anemic White Rats. Int J Multidiscip Educ Res. 2020;5(2):1-6. http://www.educationjournal.in/archives/2020/vol5/issue2/5-1-25
16. Umrah A St. Pengaruh Konsumsi Kacang Merah Terhadap Pengobatan Anemia Pada Ibu Hamil Di Puskesmas Sendana Kota Palopo. J voice midwifery. 2018;08(01):688-695. https://www.journal.umpalopo.ac.id/index.php/VoM/article/view/3
17. Murtini G. Farmasetika Dasar. Kemenkes RI. Published online 2016:168. http://bppsdmk.kemkes.go.id/pusdiksdmk/wp-content/uploads/2017/08/Farmestika-Komprehensif.pdf
18. Pratiwi Cahya Skania, Djaswadi Dasuki FSU. The Effect Of Fe Tablet Consumption On Hemoglobin (Hb) Increase In Pregnant Women: A Systematic Literature Review. Midwiferia J Kebidanan. 2021;7(1):8-13. doi:oi: 10.21070/midwiferia.v%vi%i.568
19. Uluwiyatun U, Runjati R, Suwondo A. Pengaruh Konsumsi Rumput Laut (Eucheuma Sp) terhadap Peningkatan Kadar Hemoglobin dan Status Fe Ibu Hamil Anemia di Kabupaten Pekalongan. J Kebidanan. 2015;3(7):8-15. doi:https://doi.org/10.31983/jkb.v3i7.117
20. Petry N, Boy E, Wirth JP, Hurrell RF. Review: The potential of the common bean (phaseolus vulgaris) as a vehicle for iron biofortification. Nutrients. 2015;7(2):1144-1173. doi:10.3390/nu7021144
21. Wahyuni C, Natalia S, Rohmah M, et al. The effct consumtion of red beans (Phaseolus VulgarisL) boiled on hemoglob in levelsin adolescent in institute of health science strada Indonesia. Eur J Mol Clin Med. 2020;7(2):4753-4759. https://ejmcm.com/article_3058.html
22. Mana TA et all. Peningkatan nilai hemoglobin, MCV, MCH, dan feritin pada kasus anemia defisiensi besi dengan ramuan jamu di klinik Saintifikasi Jamu Hortus Medicus. Media Gizi Mikro Indones. 2017;8(2):127-26. doi:https://doi.org/10.22435/mgmi.v8i2.604
23. Susiloningtyas I. Pemberian zat besi (Fe) dalam Kehamilan. Maj Ilm Sultan Agung. 2019;20(128):73-99.
24. Butar Butar, Gabriella Jasmine D. Penngaruh Pemberian Jus Kacang Merah Soya terhadap kadar hemoglobin pada remaja putri. Semant Sch. Published online 2020. doi:https://www.semanticscholar.org/paper/Pengaruh-Pemberian-Jus-Kacang-Merah-Soya-terhadap-Butar-Par’i/5935702da5b8ac362183353e7129d8c4b8098ee4
25. Hariya Fitri F, Susilowati D, Kurniarum A. Pengaruh Konsumsi Jus Kacang Merah (Phaseolus Vulgaris) Terhadap Kadar Hemoglobin Remaja Putri Di Pondok Pesantren Nurul Quran Kecamatan Kokap Kabupaten Kulon Progo Provinsi Daerah Istimewa Yogyakarta. J Midwifery Sci Women’s Heal. 2022;2(2):60-66. doi:10.36082/jmswh.v2i2.513
26. Aliviameita A, Puspitasari. Buku Ajar Hematologi.; 2019. doi:https://doi.org/10.21070/2019/978-623-7578-00-0
27. Arwani, Hardhono Susanto, Dian Ratna Sawitri AR, Khristophorus Heri Nugroho Hario Seno, Bagoes Widjanarko EE. The Influence of Family-Centered Nursing and Spiritual Therapies on Self-Management and Glycated Hemoglobin A. J Int Dent Med Res. 2018;11(3):1636-1639. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067013194&partnerID=40&md5=3ecc16194d87f2064958f5a3c125c939
28. Arianti M. Potensi senyawa antioksidan alami pada berbagai jenis kacang. Ilmu Gizi Indones. 2018;1(2):134-143. doi:https://doi.org/10.35842/ilgi.v1i2.7
29. Rodríguez L, Mendez D, Montecino H, et al. Role of Phaseolus vulgaris L. in the Prevention of Cardiovascular Diseases-Cardioprotective Potential of Bioactive Compounds. J Akad. 2022;11(2). doi:10.3390/plants11020186
30. Qin G, Wang F, Liang H, et al. Subchronic Study of a White Kidney Bean (Phaseolus vulgaris) Extract with ? -Amylase Inhibitory Activity. Biomed Res Int. 2019;2019. doi:10.1155/2019/9272345