Salam Leaf Nanoparticles Against Hemoglobin, Erythrocyte Hematocrit Levels Adolescent Girls Anemia

Abstract

Adolescent girls are a vulnerable group who experience iron deficiency anemia. This is due to the high need for iron during growth and development physically, mentally and in daily activities.1 Bay leaves contain iron as much as 19.8 mg/100 g bay leaf extract and Vitamin C as much as 82.2 mg. /1 g salam leaf extract.The aim of the study was To determine the effect of giving salam leaf nanoparticles to increase hemoglobin, hematocrit and erythrocyte levels in adolescent girls with anemia. This type of research is True Experiment research with randomized pretest and posttest with control group design. The independent variables were salam leaf nanoparticles with a dose of 1500 mg, the dependent variables were hemoglobin, hematocrit and erythrocytes. The number of samples in this study were 30 anemic adolescent girls who were divided into 2 groups, 15 were the intervention group and 15 were the control group.The results of this study are the Salam leaf nanoparticles combined with Fe tablets given for 14 days were proven to increase hemoglobin levels (p = 0.019), hematocrit levels (p = 0.005) and erythrocyte levels (p = 0.011). Mean ±SD intervention group and control group hemoglobin 11.84±0.65 vs 11.04±0.79, hematocrit 34.71±1.74 vs 32.60±2.05 and erythrocytes 3.88±0.30 vs 3.56±0.20. The difference in increase was higher in the intervention group compared to the control group. The administration of salam leaf nanoparticles and Fe tablets can increase the hemoglobin, hematocrit and erythrocyte levels of anemic adolescent girls compared to the control group who were only given Fe tablets.