Study of Prescribing Patterns of Drugs in Coronary Artery Disease in a Tertiary Care Hospital: A Prospective and Observational Study
Corresponding Author(s) : Shravani Karnekanti
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 9 No. 3 (2021): 2021 Volume - 9 Issue - 3
Abstract
Aims and objectives
The current study aims to study the prescription pattern of drugs in coronary artery disease patients in a tertiary care hospital.
Method
This is a prospective observational study conducted for six months. The study was conducted at AWAREGLENEAGLES GLOBAL HOSPITAL, L.B NAGAR. Patients who were admitted to the inpatient cardiology unit of the hospital for six months from December 2020 to May 2021 were enrolled in the study. A total of 80 patients were included in the study that fulfilled both the exclusion and inclusion criteria. The study-related data was collected from the patient care record in a specially designed patient profile form which included all the details of the patients such as demographics, prescriptions, medical records, doctor’s notes, nursing notes etc.
Results
The incidence of occurrence of coronary artery disease was more in male patients who are smokers and alcohol consumers. The risk for coronary artery disease mostly belonged to the age between 51-60 years. Hypertension and type II diabetes mellitus were among the most common co-morbid conditions that were associated with the increasing incidence of coronary artery disease. The most commonly prescribed drug classes from main indications in coronary artery disease were anti-platelets 132 (16%) followed by the use of anti-hyperlipidemic drugs104 (12%), vasodilators 62 (7%), and anti-coagulants 50 (6%). Among the hyperlipidemic drugs, Rosuvastatin 58 (55.76%) was prescribed most commonly. Among the anti-coagulants used enoxaparin 32 (64%) was most commonly prescribed followed by heparin 14 (28%), acenocoumarol 4 (8%), and 64 (48.5%) patients anti-platelet clopidogrel was given.
Conclusion
The results of this study on drug prescribing patterns will give a framework for continuous prescription audits during a hospital in-patient setting. This can facilitate prescribers to improve patient management by prescribing practices. Moreover, time to time studies is needed to assess drug utilization pattern for upgrading disease treatment strategy and improving quality of life of patients.
Keywords
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[2]. "Coronary Artery Disease (CAD)". 12 March 2013. Archived from the original on 2 March 2015.Retrieved 23 February 2015.
[3]. Mendis S, Puska P, Norrving B (2011). Global atlas on cardiovascular disease prevention and control (PDF) (1st ed.). Geneva: World Health Organization in collaboration with the World Heart Federation and the World Stroke Organization.pp.3–18.
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[5]. GBD 2013 Mortality Causes of Death Collaborators (January2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013". Lancet. 385 (9963):117–71. Doi:10.1016/S0140-6736(14)61682-2. PMC4340604. PMID25530442.
[6]. Misra A, Nigam P, Hills AP, et al. Consensus physical activity guidelines for Asian Indians. Diabetes TechnolTher2012; 14:83–98.
[7]. Lloyd-Jones D, Adams RJ, Brown TM, et al. Heart disease and stroke statistics—2010 update: are port from the American Heart Association.Circulation2010;121:e46–e215.
[8]. Allender S, Peto V, Scarborough F, Boxer A, Rayner M., Coronary Heart Disease Statistics 20072007ed.LondonBritishHeartFoundationUK.
[9]. Reddy KS, Yusuf S .Emerging epidemic of cardiovascular disease in developing countries.Circulation1998; 97:596–601.
[10]. Jenna Johny, K. Krishna Kumar, L. Panayapan, Rosmin Jacob: Prescription Pattern of Statins in Coronary Artery Disease: A Review; IJPBS 2017; 7(2): 20-22.
[11]. Dr Pravin S. Rathod: Drug prescribing pattern in indoor patients of coronary artery disease in a tertiary care hospital attached to a Government Medical College of Maharashtra: a retrospective study; IJAR,Sept 2017, 7 (9):32-34.
[12]. A Jonathan Arland, K Muthu Selvan, R Shyam Sundar, Dr. G Gopala Krishnan and Dr. M Senthil Velan: Study on drug utilization of anti-platelets and anticoagulants in patients with coronary artery disease; The Pharma Innovation Journal 2019; 8(7): 80-85.
[13]. Shamna C , Neenu Babu , Sreelekshmi V S , Philip John Sebastian1 , Nithin Manohar R , Prasobh G Nair , I John wisely: Analysis of Prescription Pattern and Impact of Patient Counselling in the Quality of life of Patients with Coronary Artery Disease: A Pilot Study; JMSCR. 2019 Apr; 7(4): 917-924.
[14]. Sreelekshmi V. S., Philip John Sebastian, Shamna C., Neenu Babu, Nithin Manohar R: Assessment of proportion and prescribing trends of coronary artery diseases in a tertiary care hospital, Kerala: a prospective observational study; Int J Adv Med. 2021 Jan;8(1):75-8
[15]. Dr. Swapna Phukan, Dr. Smita Bhowmik and Dr. Himmat S Rathore: A prospective study of prescription pattern in patients with coronary artery disease at a tertiary care teaching hospital; IJAR. 2019; 5(7): 01-07.
[16]. Dr Pravin S. Rathod: Drug prescribing pattern in indoor patients of coronary artery disease in a tertiary care hospital attached to a Government Medical College of Maharashtra: a retrospective study; IJAR, Sept 2017, 7 (9):32-34.
[17]. Pranay Wal, Ankita Wal, Vandana R. Nair, A. K. Rai, and Umeshwar Pandey: Management of coronary artery disease in a Tertiary Care Hospital; J Basic Clin Pharm 2013; 4(2): 31–35.
[18]. Battu Rakesh, Dr. B.S. Suresha, Jaladi Himaja , Emilda. T.Joy , Angitha Rose Varghese: Assessment of prescribing pattern in coronary artery disease; In. J. of Allied Med. Sci. and Clin. Research 2016; 4(4): 698-715.
References
[2]. "Coronary Artery Disease (CAD)". 12 March 2013. Archived from the original on 2 March 2015.Retrieved 23 February 2015.
[3]. Mendis S, Puska P, Norrving B (2011). Global atlas on cardiovascular disease prevention and control (PDF) (1st ed.). Geneva: World Health Organization in collaboration with the World Heart Federation and the World Stroke Organization.pp.3–18.
[4]. "Ischemic Heart Disease". National Heart, Lung and Blood Institute (NHLBI). Retrieved 2February2019.
[5]. GBD 2013 Mortality Causes of Death Collaborators (January2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013". Lancet. 385 (9963):117–71. Doi:10.1016/S0140-6736(14)61682-2. PMC4340604. PMID25530442.
[6]. Misra A, Nigam P, Hills AP, et al. Consensus physical activity guidelines for Asian Indians. Diabetes TechnolTher2012; 14:83–98.
[7]. Lloyd-Jones D, Adams RJ, Brown TM, et al. Heart disease and stroke statistics—2010 update: are port from the American Heart Association.Circulation2010;121:e46–e215.
[8]. Allender S, Peto V, Scarborough F, Boxer A, Rayner M., Coronary Heart Disease Statistics 20072007ed.LondonBritishHeartFoundationUK.
[9]. Reddy KS, Yusuf S .Emerging epidemic of cardiovascular disease in developing countries.Circulation1998; 97:596–601.
[10]. Jenna Johny, K. Krishna Kumar, L. Panayapan, Rosmin Jacob: Prescription Pattern of Statins in Coronary Artery Disease: A Review; IJPBS 2017; 7(2): 20-22.
[11]. Dr Pravin S. Rathod: Drug prescribing pattern in indoor patients of coronary artery disease in a tertiary care hospital attached to a Government Medical College of Maharashtra: a retrospective study; IJAR,Sept 2017, 7 (9):32-34.
[12]. A Jonathan Arland, K Muthu Selvan, R Shyam Sundar, Dr. G Gopala Krishnan and Dr. M Senthil Velan: Study on drug utilization of anti-platelets and anticoagulants in patients with coronary artery disease; The Pharma Innovation Journal 2019; 8(7): 80-85.
[13]. Shamna C , Neenu Babu , Sreelekshmi V S , Philip John Sebastian1 , Nithin Manohar R , Prasobh G Nair , I John wisely: Analysis of Prescription Pattern and Impact of Patient Counselling in the Quality of life of Patients with Coronary Artery Disease: A Pilot Study; JMSCR. 2019 Apr; 7(4): 917-924.
[14]. Sreelekshmi V. S., Philip John Sebastian, Shamna C., Neenu Babu, Nithin Manohar R: Assessment of proportion and prescribing trends of coronary artery diseases in a tertiary care hospital, Kerala: a prospective observational study; Int J Adv Med. 2021 Jan;8(1):75-8
[15]. Dr. Swapna Phukan, Dr. Smita Bhowmik and Dr. Himmat S Rathore: A prospective study of prescription pattern in patients with coronary artery disease at a tertiary care teaching hospital; IJAR. 2019; 5(7): 01-07.
[16]. Dr Pravin S. Rathod: Drug prescribing pattern in indoor patients of coronary artery disease in a tertiary care hospital attached to a Government Medical College of Maharashtra: a retrospective study; IJAR, Sept 2017, 7 (9):32-34.
[17]. Pranay Wal, Ankita Wal, Vandana R. Nair, A. K. Rai, and Umeshwar Pandey: Management of coronary artery disease in a Tertiary Care Hospital; J Basic Clin Pharm 2013; 4(2): 31–35.
[18]. Battu Rakesh, Dr. B.S. Suresha, Jaladi Himaja , Emilda. T.Joy , Angitha Rose Varghese: Assessment of prescribing pattern in coronary artery disease; In. J. of Allied Med. Sci. and Clin. Research 2016; 4(4): 698-715.