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Systemic precipitation of underlying arterial thrombosis in a COVID-19 infected patients.
Corresponding Author(s) : Dr. Dipanjali Mahanta Mahanta
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 9 No. 3 (2021): 2021 Volume - 9 Issue - 3
Abstract
Pandemic COVID-19 has brought forward a wide array of organ-specific and systemic disorders, one such being raised susceptibility towards development of systemic coagulopathies (venous, arterial or microvascular thrombi), which often contributes to the high incidence of thrombotic complications, such as deep venous thrombosis, pulmonary embolism, associated with common thrombotic arterial complications (eg, limb ischemia, ischemic stroke, myocardial infarction) in critically ill patients. A similar picture is also seems to have been painted in our cases discussed below, whereby underlying SARS CoV 2 infection has predisposed patients to hypercoagulability-related disorders including thrombosis and other fatal vascular events. Making the start of prompt antithrombosis prophylaxis are necessary to ensure better recovery in both the pre-operative and post operative period and regular re-evaluation of basic investigations (PT-INR, aPTT, D-Dimer) to ensure timely action for any change, enabling optimal patient care and recovery.
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References
2. Bon-Wook Koo, Hyo-Seok Na, Young-Tae Jeon, Jung-Won Hwang, and Sang-Hwan Do. The influence of propofol and sevoflurane on hemostasis: a rotational thromboelastographic study.Anesth Pain Med 2014; 9: 292-297.
3. Platelets, Perioperative Hemostasis, and Anesthesia. Anesthesiology, V 96, No 5, May 2002.
4. F.A. Kloka,?, M.J.H.A. Kruipb, N.J.M. van der Meer et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19.Thrombosis Research 191 (2020) 145–147.
5. Coagulation abnormalities and thrombosis in patients with COVID-19.May 11, 2020, https://doi.org/10.1016/S2352-3026(20)30145-9.
6. Wei Shi, JiagaoLv, Li Lin. Coagulopathy in COVID-19: Focus on vascular thrombotic events. Journal of Molecular and Cellular Cardiology (2019), https://doi.org/10.1016/j.yjmcc.2020.07.003.
7. Marco Marietta,ValeriaColuccio, Mario Luppi et al.COVID?19, coagulopathy and venous thromboembolism: more
questions than answers. Internal and Emergency Medicine July 2020. https://doi.org/10.1007/s11739-020-02432-x.
