TY - JOUR AU - Bhavana Salunke, AU - Dr. Sangeeta Asija, AU - Dr. Rajesh Asija, AU - Anil Kumar Goyal, AU - Jitendra Kumar, PY - 2021/01/13 Y2 - 2024/03/28 TI - Formulation Designing of Taste masked Dry Syrup of Ciprofloxacin HCL JF - International Journal of Allied Medical Sciences and Clinical Research JA - ijamscr VL - 8 IS - 4 SE - Articles DO - 10.61096/ijamscr.v8.iss4.2020.760-767 UR - https://ijamscr.com/ijamscr/article/view/949 SP - 760-767 AB - <p>Taste masking and development of palatable dosage forms of bitter drugs constitutes the objective of many a research project in the field of pharmaceutical technology. Taste is an important factor in the development of dosage form. The problem of bitter and obnoxious taste of drug in pediatric patient can create a bad psychological effect on mind. The purpose of this research was to mask the intensely bitter taste of Ciprofloxacin is a broad spectrum antibiotic. It is extremely bitter taste resulting in poor patient’s compliance. The aim of present work was to prepare drug resin complex (DRC) using ion exchange resin (Kyron T114) for taste masking and formulate oral reconstituable dry syrup. Formulated ciprofloxacin reconstituable dry syrup has acceptable Drug Dissolution properties. In evaluating period of 7 days no significant change was observed in pH, sedimentation volume, specific gravityand drug content.From the results it concluded that effective taste masking of ciprofloxacin was achieve using Kyron T114 and successfully evaluated in reconstituable dry syrup.</p> ER -