@article{Nallani Venkata Rama Rao_A. Narendra Babu_M. Sathish Kumar_P. Sharmila Nirojini_Venkatarao Vutla_Ramarao Nadendla_2020, title={Evaluation of anti diabetic potential of leaves of nelumbo nucifera in streptozotocin induced diabetic rats}, volume={1}, url={https://ijamscr.com/ijamscr/article/view/41}, DOI={10.61096/ijamscr.v1.iss1.2013.18-24}, abstractNote={<p><em>Nelumbo nucifera</em> Gaertn. (Nymphaeaceae), also known as sacred lotus, is a well known medicinal plant. <em>Nelumbo nucifera </em> (family Nymphaeaceae) are free floating plants.The methanolic extract of <em>Nelumbo nucifera</em>  leaves was obtained by soxhlet extraction apparatus. The extract was  subjected to preliminary  phytochemical screening by using standard procedures.The toxicity studies and dose fixation were carried out by using OECD 425 guideline. According to OECD 425 guideline toxicity study no toxic symptoms were observed up to dose 2000 mg/kg.The anti diabetic effect of <em><u>Nelumbo nucifera</u></em> leaf methanolic extract  given in streptozotocin induced diabetic rats. Oral administration of methanolic extract  for 15 days in diabetic mice exhibits highly significant (P < 0.01)  antidiabetic activity and also alters the body weight significantly . The data were analyzed using analysis of variance followed by Dunnett’s test.The observations confirm that methanolic extract of <em>NELUMBO NUCIFERA</em> leaf and stem has antidiabetic activity  due to presence of alkaloids,aminoacids, saponins, glycosides, triterpenoid, vitamins etc   There is a need of further investigation to isolate and identify the principle chemical constituents for its anti diabetic property.</p>}, number={1}, journal={International Journal of Allied Medical Sciences and Clinical Research}, author={Nallani Venkata Rama Rao and A. Narendra Babu and M. Sathish Kumar and P. Sharmila Nirojini and Venkatarao Vutla and Ramarao Nadendla}, year={2020}, month={Jul.}, pages={18–24} }