Gidwani BK et al. reported the anti-inflammatory activity of aqueous extract of Lantana camara in albino rats. Extract treatment (500mg/kg body weight) significantly decreased paw volume in carrageenan induced paw oedema test in rats [25].

De Mello FB et al. Studied the Effects of hydroalcoholic extract of Lantana camara leaves on fertility, general reproductive performance and teratology in female albino Wistar rats. The extract interfered in the frequency of fetal skeleton anomalies from dams treated with the extract and induced embryo toxicity as indicated by postimplantation loss, without any signs of maternal toxicity [26].

Gomes de Melo J et al. Studied Wound healing property of ethanol extract of leaf of Lantana camarain adult male Wister rats. Topical application of the extract over the wound significantly increased the wound healing activity. Histological analyses of healed wounds confirmed the role of extract in healing [27].

Latha LY et al. Studied wound healing activity of aqueous extract of leaf of Lantana camara in rats. Topical application of the extract on the wound (100 mg/kg/day) significantly enhanced the rate of wound contraction (98%), synthesis of collagen and decreased wound healing time [28].

Srivastava D et al. screened Anti-fungal potential of Lantana camaraagainst Alternaria sp. which causes different plant diseases especially in vegetable plants. The antifungal activity was performed by food poison plate method at three different concentrations of extract viz, 10 mg/ml, 15 mg/ml and 20 mg/ml. At 20mg/ml dose Lantana camara exhibited significant antifungal activity against Alternaria spores [29].

Tripathi S et al. screened Antifungal activity of ethanol and hot water extract of Lantana camara against wood destroying white and brown rot fungi. Both extracts exhibited efficient antifungal activity against white and brown rot fungi, however ethanol extract was highly potential at very low concentration (0.01%) [30].

Sagar L et al. evaluated antimotility activity of Methanol extract of Lantana camara leaves in mice. Intestinal motility was assayed by charcoal meal test in mice. At a dose of 1 g/kg body weight, the extract completely inhibited the transit of charcoal in normal mice. Intraperitoneal administration of 125 and 250 mg/kg body weight the extracts significantly reduced the fecal output in castor oil induced diarrhoea in mice [31].

Barre JT et al. reported the anti- mutagenic activity of Lantana camara. 22β-acetoxylantic acid and 22β-dimethylacryloyloxy lantanolic acid from Lantana camara showed antimutagenic activity. The antimutagenicity test was performed by micronucleus test in Swiss mice. Both compounds exhibited high antimutagenic activity in Mitomycin C induced mutagenesis in mice [32].

Kalita S et al. performed the hemolytic activity of Lantana camara aqueous extract and its solvent fractions by modified spectroscopic method at four different concentrations (125, 250, 500, 1000 μg/ml). The aqueous extract and its solvent fractions exhibited very low hemolytic activity towards the human erythrocytes. The hemolytic activity of the different extracts was found in the following order: chloroform fraction > hexane and ethyl acetate fraction (50:50) > aqueous extract > ethanol fraction >methanol fraction [33].

Pour BM et al. reported the Anticancer and antiproliferative activity. Oleanonic acid isolated from Lantana camara was screened for anticancer activity against a murine tumour (Ehrlich ascites carcinoma), and three human cancer cell lines, namely A375 (malignant skin melanoma), Hep2 (epidermoid laryngeal carcinoma) and U937 (lymphoma). Oleanonic acid exhibited promising cytotoxicity against A375 cells [34].

Gosh S et al. reported the cytotoxicity effect of Leaves of Lantana camara on Vero cell line. In vitro cytotoxicity test was performed by MTT assay. The methanol extract (500 µg/ml) concentration inhibited the growth of cells 2.5 times less than did Triton 100 × 1% [35].

Ganesh T et al. reported Antihyperglycemic activity of methanol extract of leaves Lantana camarain alloxan induced diabetic rats. Oral administration of the methanol extract of Lantana camara (400 mg/kg body weight) leaves resulted in decrease in blood glucose level to 121.94 mg/dl in alloxan induced diabetic rats [36].

Venkatachalam T et al. screened Hypoglycemic activity of methanol extract of Lantana camara Linn fruits in streptozotocin induced diabetic rats (Wistar albino rats). Extract treatment at doses of 100 and 200 mg/kg body weight resulted in dose dependent decrease in serum glucose level in streptozotocin induced diabetic rats. Extract treatment also showed improvement in body weight, HbA1c profile as well as regeneration of liver cells [37].

Thamotharan G et al. Reported Antiulcerogenic activity of the methanol extract of leaves of Lantana camara on asprin, ethanol and cold resistant stress induced gastric lesions in rats. Pre‐treatment of the effected rats with the extract (200 and 400 mg/kg body weight) showed significant protective effect in aspirin induced, ethanol induced and cold restraint stress induced ulcers in rats. The extract resulted in dose dependent antiulcerogenic activity in all models [38].

Mishara N et al. reported Antifilerial activity of crude extract of Lantana camara stem. The extract and its chloroform fraction resulted in the death of adult Brugia malayi and sterilised most of the surviving female worms in the rodent model Mastomyscoucha [39].

Bhakta D et al. evaluated Antioxidant activity of the leaves of Lantana camara by reducing power activity and 1, 1- diphenyl2- picrylhydrazyl (DPPH) radical scavenging assay. Leaves extracts exhibited high antioxidant effect, however younger leaves exhibited strong antioxidant activity than the older or matured leaves [40].

Mayee R et al. reported, the Ethanolic extract of Lantana camara exhibited significant antioxidant activity in in vivo studies. The extract treatment decreased the extent of lipid peroxidation in the kidneys of urolithic rats. In vitro studied were carried out by DPPH radical scavenging assay and Nitric oxide free radical scavenging assay. Extract exhibited high antioxidant properties in both the assays [41].

Barreto FS et al. reported the Ethanolic extracts of Lantana camara leaves and roots for antibacterial activity. The in vitro antibacterial activity was performed by microdilution method. The extracts exhibited antimicrobial activity against Staphylococcus aureus, Proteus vulgaris, Pseudomonas aeruginosa, Víbrio cholareae, Escherichia coli and two multiresistant strains E. coli and S. aureus [42].

Ganjewala D et al. studied, Three different solvent extract of leaves and flowers of four different varities of Lantana camaraexhibited significant antibacterial activity E. coli, Bacillus subtilis and P. aeruginosa whereas poor antibacterial activity against Staphylococcus aureus [43].

Badakhshan MP et al. screened the Methanolic extracts of different parts of Lantana camara for antimicrobial activity against 10 bacteria and 5 fungi by disk diffusion method and broth microdilution method. The leaves extract of Lantana camara showed highest activity against Gram positive Bacillus cereus and Gram negative Salmonella typhi [44]

Kumar SM et al. investigated ethanolic extract (10, 50, 100mg/ml concentration) of Lantana camara for its anthelmintic activity against pheretima posthuma due to presence of tannins which bind to proteins in the GIT of host animal or glycoprotein on the cuticle of parasite and cause death [45].