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  <front>
    <article-meta>
      <title-group>
        <article-title>Combination of oxytocin massage and dried dates on the amount of postpartum hemorrhage and involution uterine in normal postpartum</article-title>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="person">
          <name>
            <given-names>Sri Wahyuni</given-names>
          </name>
          <email>inyun.azure@gmail.com</email>
          <xref ref-type="aff" rid="aff-1"/>
        </contrib>
      </contrib-group>
      <aff id="aff-1">
        <institution>Poltekkes Kemenkes Semarang / Semarang, Indonesia</institution>
        <country>Indonesia</country>
      </aff>
      <history>
        <date date-type="received" iso-8601-date="2020-08-11">
          <day>11</day>
          <month>08</month>
          <year>2020</year>
        </date>
        <date data-type="published" iso-8601-date="2020-08-11">
          <day>11</day>
          <month>08</month>
          <year>2020</year>
        </date>
      </history>
    </article-meta>
  </front>
  <body>
    <fig>
      <graphic mimetype="image" mime-subtype="jpeg" xlink:href="image1.jpeg"/>
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    <p>
      <bold>www.ijamscr.com</bold>
    </p>
    <p>
      <bold>Combination of oxytocin massage and dried dates on the amount of postpartum hemorrhage and involution uterine in normal postpartum</bold>
    </p>
    <p>
      <bold>Sri Wahyuni*</bold>
      <bold>
        <sup>1</sup>
      </bold>
      <bold>, Ariawan Soejoenoes</bold>
      <bold>
        <sup>2</sup>
      </bold>
      <bold> and Runjati</bold>
      <bold>
        <sup>3</sup>
      </bold>
    </p>
    <p>
      <italic>
        <sup>1</sup>
      </italic>
      <italic>Poltekkes Kemenkes</italic>
      <italic> Semarang / Semarang, Indonesia</italic>
    </p>
    <p>
      <italic>
        <sup>2</sup>
      </italic>
      <italic>Poltekkes Kemenkes</italic>
      <italic> Semarang / Semarang, Indonesia</italic>
    </p>
    <p>
      <italic>
        <sup>3</sup>
      </italic>
      <italic>Poltekkes Kemenkes</italic>
      <italic> Semarang / Semarang, Indonesia</italic>
    </p>
    <p>
      <bold>* Corresponding author: Sri Wahyuni</bold>
    </p>
    <p>
      <bold>Email: inyun.azure@gmail.com</bold>
    </p>
    <sec id="sec-1">
      <title>Abstract</title>
      <sec id="sec-1_1">
        <title>Background</title>
        <p>The range incidence of postpartum hemorrhage  from 5% - 15%, and  40%-50% is caused by a lack of adequate contractions. Oxytocin Massage can stimulate the release of oxytocin which plays an important role in uterine contractions after labor, while dried dates contain potassium as a neurotransmitter that affects of the uterine muscles and calcium which helps the blood clotting process.</p>
      </sec>
      <sec id="sec-1_2">
        <title>Objective</title>
        <p>Proving the combination of oxytocin massage and consumption of dried dates is more effective against the amount of postpartum hemorrhage andinvolution  uterine in normal postpartum.</p>
      </sec>
      <sec id="sec-1_3">
        <title>Method</title>
        <p><italic>Quasy experimental</italic> with <italic>posttest only design</italic>. Respondents were who gave birth in September 2018 as many as 45 respondents. Divided into 3 groups, the first group is the oxytocin massage intervention, the second group is the dried datesfruit intervention and the third group is the combination intervention. The statistical test used by <italic>Friedman, Kruskal Wallis </italic>and <italic>Chi-Square.</italic></p>
      </sec>
      <sec id="sec-1_4">
        <title>Results</title>
        <p>The amount of postpartum hemorrhage at2 hours postpartum <italic>p</italic>&gt; 0.05.While 6 hours and 12 hours postpartum <italic>p</italic>&lt; 0.05. The combination group showed the lowest average of 23 ml. While involution uterine at 6 hours postpartum <italic>p</italic>&gt; 0.05 while on  day 3 and on day 6 postpartum<italic>p</italic>&lt;0.05. The combination group showed the lowest average of 3.94 cm. The combination of oxytocin massage and dried date fruit is more effective against postpartum hemorrhage and involution uterine.</p>
      </sec>
      <sec id="sec-1_5">
        <title>Conclusions and Recommendations</title>
        <p>In additional midwifery service, the use of oxytocin massage and consumption of dried dates is highly recommended to amount of postpartum hemorrhage and involution uterine.</p>
        <p>Keywords: Oxytocin Massage, Dried Dates, Postpartum hemorrhage, Involution uterine.</p>
      </sec>
    </sec>
    <sec id="sec-2"/>
    <sec id="sec-3"/>
    <sec id="sec-4">
      <title>Introduction</title>
      <p>Excessive uterine stretching, prolonged labor, and labor with action are among the risk factors that influence the occurrence of postpartum hemorrhage. Which if not addressed can lead to postpartum depression, hemorrhagic shock and even cause death. [1] </p>
      <p>The frequency of postpartum hemorrhage in developed and developing countries ranges from 5% -15%, and from that number 40-50% is caused by a lack of uterine contractions. Adequate and followed by the loss of the placenta, 23-24%. In 2013 postpartum hemorrhage caused maternal mortality by 30.3% in Indonesia followed by hypertension as much as 27.1%. [2] </p>
      <p>Oxytocin Massage can stimulate the release of the hormone oxytocin which plays an important role in labor, childbirth and breastfeeding.<ext-link xlink:href="file:///\\192.168.1.13\i\Journal%20Work\IJAMSCR\Formatting\2019\January\New%20folder\IJAMSCR-19-114%20-ORG.docx">[3]</ext-link> In addition to oxytocin massage, another action that can help increase uterine contraction in postpartum is to consume dried dates because it contains Potassium which functions as a neurotransmitter that can affect against the work of muscle contraction while the calcium content plays a role in the process of blood clotting and prevents the body from losing a lot of blood. [4] </p>
      <p>Dates also have a lot of glucose and fructose which is the most important source of energy in the body and is also the best food for the movement of uterine muscles that are very necessary during labor and after delivery, absorption of sugar in dates faster than rice which is 40 -45 minutes only. [5] </p>
      <sec id="sec-4_1">
        <title>Study Objectives</title>
        <p>Proving the combination of oxytocin massage and consumption of dried dates is more effective against the amount of postpartum hemorrhage and involution uterine in normal postpartum.</p>
      </sec>
    </sec>
    <sec id="sec-5">
      <title>Methods</title>
      <p>This research is an <italic>Quasy</italic><italic>Experimental </italic>with <italic>Posttest Only Design,</italic>Respondents were who gave birth at working areas of Banjarbaru Health Center South Kalimantan in September 2018 as many as 45 respondents. Divided into 3 groups, the first group is the oxytocin massage intervention, the second group is the dried dates fruit intervention and the third group is the combination intervention. which met the inclusion and the exclusion criteria. The sampling method used was <italic>cluster sampling</italic> and the statistical test used by <italic>Friedman, Kruskal Wallis and Mann-Whitney.</italic></p>
      <sec id="sec-5_1">
        <title>Data Analysis </title>
        <p>Univariate analysis to calculate the mean, and standard devisiation value intersection the characteristics of respondents. Bivariate analysis is used to determine the differences between research variables, the data are abnormally distributed so that it uses a non-parametric test. To test the amount of postpartum haemorrhage and involution uterine covery decrease in height fundus uterine using the<italic> Friedman and Kruskal Wallis</italic>, to test the type of <italic>lochea</italic> using <italic>Chi square</italic>&lt;0.05.</p>
      </sec>
    </sec>
    <sec id="sec-6"/>
    <sec id="sec-7">
      <title>Result</title>
      <sec id="sec-7_1">
        <title>Univariate Analysis</title>
        <p>The amount of Postpartum hemorrhage at 2 hours postpartum <italic>p value</italic> = 0.708 or <italic>p</italic>&gt; 0.05.While at 6 hours and 12 hours postpartum <italic>p value</italic>&lt; 0.05.Which means there is a significant difference in the amount of postpartum hemorrhage at 6 hours and 12 hours postpartum after giving intervention in each group.</p>
        <p>
          <bold>Table 4.1</bold>
          <bold>Average amount of Postpartum hemorrhage in Oxytocin Massage, Dried Dates and Combinations</bold>
          <bold> groups.</bold>
        </p>
        <table-wrap>
          <table>
            <tr>
              <td rowspan="2">
                <bold>Group  </bold>
              </td>
              <td colspan="5">
                <bold>Range of postpartum hemorrhage</bold>
              </td>
              <td>
                <bold>
                  <italic>P-value</italic>
                </bold>
              </td>
            </tr>
            <tr>
              <td/>
              <td>
                <bold>2 hour Postpartum</bold>
                <bold>Mean ± SD</bold>
              </td>
              <td>
                <bold>Δ</bold>
              </td>
              <td>
                <bold>6 hour Postpartum</bold>
                <bold>Mean ± SD</bold>
              </td>
              <td>
                <bold>Δ</bold>
              </td>
              <td>
                <bold>12 hour Postpartum</bold>
                <bold>Mean ± SD</bold>
              </td>
              <td/>
            </tr>
            <tr>
              <td>Oxytocin massage</td>
              <td>73.5 ± 25</td>
              <td>23.5</td>
              <td>71.3 ± 19.5</td>
              <td>14.6</td>
              <td>67.3 ± 17.2</td>
              <td>0.000<sup>a</sup></td>
            </tr>
            <tr>
              <td>Dried dates</td>
              <td>50.3 ± 14.9</td>
              <td>24.6</td>
              <td>49.7  ±  14</td>
              <td>17.7</td>
              <td>38  ±  9.9</td>
              <td>0.000<sup>a</sup></td>
            </tr>
            <tr>
              <td>Combination </td>
              <td>32 ± 13.8</td>
              <td>29.3</td>
              <td>35.7 ± 11.1</td>
              <td>20</td>
              <td>23 ±  7.2</td>
              <td>0.000<sup>a</sup></td>
            </tr>
            <tr>
              <td>
                <italic>p-value</italic>
              </td>
              <td>0.708<sup>b</sup></td>
              <td/>
              <td>0.030<sup>b</sup></td>
              <td/>
              <td>0.005<sup>b</sup></td>
              <td/>
            </tr>
          </table>
        </table-wrap>
        <list list-type="bullet">
          <list-item>
            <p>
              <italic>Friedman        b. Kruskal Wallis</italic>
            </p>
          </list-item>
        </list>
        <p>From the graph above it can be seen that the amount of postpartum haemorrhage in the combination group showed the lowest average value compared to other groups of 23 ml.</p>
        <p>Involution Uterinecovery with measurements of height fundus uterine at 6 hours postpartum obtained a <italic>p-value</italic> = 0.89or <italic>p</italic>&gt;0.05. Whereas the measurement of height fundus uterine on day 3 and on day 6 postpartum was found to be p &lt;0.05, meaning that there was a significant difference in the decrease in uterine fundus height which was significant on day 3 and day 6 after intervention in all three groups was given.</p>
        <p>
          <bold>Table 4.2Average </bold>
          <bold>decrease</bold>
          <bold>of height fundus uterine</bold>
        </p>
        <table-wrap>
          <table>
            <tr>
              <td rowspan="2">Groups </td>
              <td colspan="6">TFU (cm)</td>
            </tr>
            <tr>
              <td/>
              <td><bold>6 hour postpartum</bold>Mean ± SD</td>
              <td>ΔMean</td>
              <td><bold>On Day 3</bold>Mean ±SD</td>
              <td>Δmean</td>
              <td><bold>On Day  6</bold>Mean ± SD</td>
              <td>
                <italic>p-value</italic>
              </td>
            </tr>
            <tr>
              <td>Oxytocin massage</td>
              <td>9.35 ± 0.52</td>
              <td>1.92</td>
              <td>9.42 ± 0.60</td>
              <td>1.88</td>
              <td>9.32 ± 0.72</td>
              <td>0.001<sup>a</sup></td>
            </tr>
            <tr>
              <td>Dried dates</td>
              <td>7.43 ± 0.68</td>
              <td>1.88</td>
              <td>7.54 ± 0.53</td>
              <td>1.73</td>
              <td>6.84 ± 0.59</td>
              <td>0.001<sup>a</sup></td>
            </tr>
            <tr>
              <td>Combination</td>
              <td>5.55 ± 0.55</td>
              <td>2.49</td>
              <td>5.81 ± 0.52</td>
              <td>2.91</td>
              <td>3.93 ± 0.96</td>
              <td>0.001<sup>a</sup></td>
            </tr>
            <tr>
              <td>P-value</td>
              <td>0.89<sup>b</sup></td>
              <td/>
              <td>0.007<sup>b</sup></td>
              <td/>
              <td>0.001<sup>b</sup></td>
              <td/>
            </tr>
          </table>
        </table-wrap>
        <list list-type="order">
          <list-item>
            <p><italic>Friedman</italic>     b. <italic>Kruskal Wallis</italic></p>
          </list-item>
        </list>
        <p>From the graph above it can be seen that the average decreaseof height fundus uterine on day 6 in the combination group showed the lowest average value compared to other groups which was 3.94 cm. in addition to the expenditure of<italic>lochea</italic> types on day 3 postpartum, most respondents with the type of <italic>locheasanguinolenta</italic> were 42 respondents (93.3%), some respondents were still with the type of <italic>lochearubra</italic> as many as 3 respondents (6.7%), and <italic>p</italic> = 0.343 or <italic>p</italic>&gt; 0.05. And on day 6 postpartum most of the respondents with <italic>lochea serosa</italic> were 31 respondents (68.9%). Some respondents were still with the type of <italic>locheasanguinolenta</italic> with 14 respondents (31.1%) and <italic>p</italic> = 0.022 or <italic>p</italic>&lt;0.05.So that it could be concluded that there were significant differences in <italic>lochea</italic> expenditure in the three groups.</p>
      </sec>
    </sec>
    <sec id="sec-8"/>
    <sec id="sec-9">
      <title>Discussion</title>
      <p>Oxytocin massage around the connective tissue will increase beta endorphin levels and the oxytocin hormone where the mother will relax so that it can reduce stress so the hormone oxytocin will be produced without obstacles. In the IV period the delivery of the hormone oxytocin plays an important role in maintaining the contraction of the uterine muscles to prevent bleeding.<ext-link xlink:href="file:///\\192.168.1.13\i\Journal%20Work\IJAMSCR\Formatting\2019\January\New%20folder\IJAMSCR-19-114%20-ORG.docx"></ext-link><ext-link xlink:href="file:///\\192.168.1.13\i\Journal%20Work\IJAMSCR\Formatting\2019\January\New%20folder\IJAMSCR-19-114%20-ORG.docx"></ext-link><ext-link xlink:href="file:///\\192.168.1.13\i\Journal%20Work\IJAMSCR\Formatting\2019\January\New%20folder\IJAMSCR-19-114%20-ORG.docx"></ext-link><ext-link xlink:href="file:///\\192.168.1.13\i\Journal%20Work\IJAMSCR\Formatting\2019\January\New%20folder\IJAMSCR-19-114%20-ORG.docx">6</ext-link><ext-link xlink:href="file:///\\192.168.1.13\i\Journal%20Work\IJAMSCR\Formatting\2019\January\New%20folder\IJAMSCR-19-114%20-ORG.docx"></ext-link></p>
      <p>Dried dates besides containing high potassium as a neotransmitter which is very necessary to maintain the work of uterine muscle contraction in postpartum, dates also contain calcium which can help accelerate blood thickening activities so that it can reduce excessive bleeding during postpartum.<ext-link xlink:href="file:///\\192.168.1.13\i\Journal%20Work\IJAMSCR\Formatting\2019\January\New%20folder\IJAMSCR-19-114%20-ORG.docx"></ext-link><ext-link xlink:href="file:///\\192.168.1.13\i\Journal%20Work\IJAMSCR\Formatting\2019\January\New%20folder\IJAMSCR-19-114%20-ORG.docx"></ext-link><ext-link xlink:href="file:///\\192.168.1.13\i\Journal%20Work\IJAMSCR\Formatting\2019\January\New%20folder\IJAMSCR-19-114%20-ORG.docx"></ext-link><ext-link xlink:href="file:///\\192.168.1.13\i\Journal%20Work\IJAMSCR\Formatting\2019\January\New%20folder\IJAMSCR-19-114%20-ORG.docx">7</ext-link><ext-link xlink:href="file:///\\192.168.1.13\i\Journal%20Work\IJAMSCR\Formatting\2019\January\New%20folder\IJAMSCR-19-114%20-ORG.docx"></ext-link></p>
    </sec>
    <sec id="sec-10">
      <title>Conclusion</title>
      <p>The combination of oxytocin massage and consumtion of dried dates is more effective and can be used as an alternative to the amount of bleeding and involution uterine.</p>
      <sec id="sec-10_1">
        <title>Recommendation Future</title>
        <p>Further researchers need to add the hormone oxytocin as a variable, and use larger sampels and study longer involution uterine.</p>
      </sec>
    </sec>
    <sec id="sec-11"/>
    <sec id="sec-12"/>
    <sec id="sec-13">
      <title>References</title>
      <list list-type="bullet">
        <list-item>
          <p>Sentilhes L, Gromez A, Clavier E,et all. Long-Trem Psychological Impact of Severe Postpartum Hemorrhage. Acta Obstetricia Et Gynecologica Scandinavica.; 90, 2011 615-20.</p>
        </list-item>
        <list-item>
          <p>Dinas Kesehatan Provinsi Kalimantan Selatan, 2013. Upaya Percepatan Pencapaian MDGs Bidang Kesehatan Di Kalimantan Selatan, Dinas Kesehatan Provinsi Kalimantan Selatan, Banjarmasin.</p>
        </list-item>
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          <p>Gita S, Saeed B. A Normal Pattern of Uterin Involution Using S-FD in Primiparous women and the prevalence of Uterin Subinvolution. Journal of Medical Sciences. 6(6) 2008, 11-14.</p>
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          <p>Khadem N. Comparing the Efficacy of Dates and Oxytocin in The Management of Postpartum Hemorrhage. Shiraz E-Medical Juornal;8,2. .2007</p>
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          <p>Saryono, Anggraeni M.D, Rahmawati E. Effects of dates fruit (Phoenix dactylifera L.) in the female reproductive process. International Journal of Recent Advances in Multidisciplinary Research. 3(7), 2016 1630-33.</p>
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          <p>Sarli D, Masrul, Agus M. Pengaruh Perbedaan Efektivitas Senam Nifas dan Pijat Oksitosin terhadap Jumlah Perdarahan pada  Ibu 2 Jam Post Partum. Jurnal Kesehatan Andalas.; 4(3), 2015 743-50.</p>
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          <p>Siddiq M, Alied SM, Kader AA. Dates: Postharvest Science, Processing Technology and Health Benefits. The Atrium, 2014.265-273.</p>
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      </list>
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