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A Multispecialty Hospital Investigation Into Prescription Pattern And Drug Interaction For COPD Patients
Corresponding Author(s) : Nivetha S R
International Journal of Allied Medical Sciences and Clinical Research,
Vol. 12 No. 1 (2024): 2024 Volume -12 - Issue 1
Abstract
Chronic obstructive pulmonary disease (COPD) is a lung disease that is characterized by a persistent blockage of airflow from the lungs. Drug utilization studies are also called as prescription pattern monitoring studies (PPMS) primarily concentrate on the prescription, dispensing, and administration of medications. The aim of the study is to optimize the drug therapy for the COPD patients in a multispecialty hospital by analyzing the drug prescribing pattern and by evaluating the drug interaction in the prescriptions. Based on study population, out of 150 patients, males were more susceptible to this disease than female. The average age of patients were found to be 45.73 30.57 years. The cases were analyzed based upon class of drugs prescribed, antibiotics, bronchodilators, antihistamines, mucolytic agent, nasal decongestants and corticosteroids were commonly prescribed. Out of which, 38.2% (n=104) antibiotics and 34.5% (n=94) bronchodilators were most commonly prescribed class of drugs. Clarithromycin, theophylline+ forgyln, montek LC, ambrodil, oxynoz and dexa were the commonly prescribed antibiotics, bronchodilators, antihistamines, mucolytic agents, nasal decongestants and corticosteroids respectively. Nearly 59 patients were given three drugs and 14 patients were given 4 drugs at a time which shows the practice of polypharmacy. The cases were also analysed for drug interaction which shows 32.7% (n=49) of minor, 27.3% (n=41) of monitor closely drug interactions respectively. The findings provide a valuable foundation for refining COPD interventions and highlight the necessity for vigilant monitoring of drug interactions during treatment.
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- Sawant MP, Padwal SL, Kale AS, Pise HN, Shinde RM. Study of drug prescription pattern among COPD patients admitted to medicine in-patient department of tertiary care hospital. Int J Basic Clin Pharmacol. 2017 Aug 22;6(9):2228. doi: 10.18203/2319-2003.ijbcp20173750.
- Cukic VC, Lovre V, Dragisic D, Ustamujic A. Asthma and chronic obstructive pulmonary disease (COPD) – differences and similarities. Mater Sociomed. 2012;24(2):100-5. doi: 10.5455/msm.2012.24.100-105, PMID 23678316.
- Ho T, Cusack RP, Chaudhary N, Satia I, Kurmi OP. Under- and over-diagnosis of COPD: a global perspective. Breathe (Sheff). 2019 Mar 1;15(1):24-35. doi: 10.1183/20734735.0346-2018, PMID 30838057.
- Mittal N, Mittal R, Singh I, Shafiq N, Malhotra S. Drug utilisation study in a tertiary Care Center: recommendations for improving hospital drug dispensing policies. Indian J Pharm Sci. 2014 Jul 1;76(4):308-14. PMID 25284928.
- V JS, D RBR, GP, L S, R NS. Review on drug utilization pattern in outpatient general department. World J Curr Med Pharm Res. 2020 Feb 10;2(1):1-3.
- Kaur S, Rajagopalan S, Kaur N, Shafiq N, Bhalla A, Pandhi P et al. Drug utilization study in medical emergency unit of a tertiary care hospital in north india. Emerg Med Int. 2014;2014:973578. doi: 10.1155/2014/973578, PMID 24883208.
- Bourbeau J, Bartlett SJ. Patient adherence in COPD. Thorax. 2008 Sep 1;63(9):831-8. doi: 10.1136/thx.2007.086041, PMID 18728206.
- Bali A, Bali D, Iyer N, Iyer M. Management of medical records: facts and figures for surgeons. J Maxillofac Oral Surg. 2011;10(3):199-202. doi: 10.1007/s12663-011-0219-8, PMID 22942587.
- belbase N. prescribing pattern of antibiotics in the treatment of pulmonary disease in tertiary care teaching hospital. Indo-. Am J Pharm Sci. 2020;7(12):1667-83.
References
Sawant MP, Padwal SL, Kale AS, Pise HN, Shinde RM. Study of drug prescription pattern among COPD patients admitted to medicine in-patient department of tertiary care hospital. Int J Basic Clin Pharmacol. 2017 Aug 22;6(9):2228. doi: 10.18203/2319-2003.ijbcp20173750.
Cukic VC, Lovre V, Dragisic D, Ustamujic A. Asthma and chronic obstructive pulmonary disease (COPD) – differences and similarities. Mater Sociomed. 2012;24(2):100-5. doi: 10.5455/msm.2012.24.100-105, PMID 23678316.
Ho T, Cusack RP, Chaudhary N, Satia I, Kurmi OP. Under- and over-diagnosis of COPD: a global perspective. Breathe (Sheff). 2019 Mar 1;15(1):24-35. doi: 10.1183/20734735.0346-2018, PMID 30838057.
Mittal N, Mittal R, Singh I, Shafiq N, Malhotra S. Drug utilisation study in a tertiary Care Center: recommendations for improving hospital drug dispensing policies. Indian J Pharm Sci. 2014 Jul 1;76(4):308-14. PMID 25284928.
V JS, D RBR, GP, L S, R NS. Review on drug utilization pattern in outpatient general department. World J Curr Med Pharm Res. 2020 Feb 10;2(1):1-3.
Kaur S, Rajagopalan S, Kaur N, Shafiq N, Bhalla A, Pandhi P et al. Drug utilization study in medical emergency unit of a tertiary care hospital in north india. Emerg Med Int. 2014;2014:973578. doi: 10.1155/2014/973578, PMID 24883208.
Bourbeau J, Bartlett SJ. Patient adherence in COPD. Thorax. 2008 Sep 1;63(9):831-8. doi: 10.1136/thx.2007.086041, PMID 18728206.
Bali A, Bali D, Iyer N, Iyer M. Management of medical records: facts and figures for surgeons. J Maxillofac Oral Surg. 2011;10(3):199-202. doi: 10.1007/s12663-011-0219-8, PMID 22942587.
belbase N. prescribing pattern of antibiotics in the treatment of pulmonary disease in tertiary care teaching hospital. Indo-. Am J Pharm Sci. 2020;7(12):1667-83.