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      <title-group>
        <article-title>Prevalence and outcome of consanguineous marriage in selected community area</article-title>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="person">
          <name>
            <given-names>Prof.Dr.S.KalaBarathi</given-names>
          </name>
          <email>ijamscr@gmail.com</email>
          <xref ref-type="aff" rid="aff-1"/>
        </contrib>
      </contrib-group>
      <aff id="aff-1">
        <institution>Principal, Saveetha College of Nursing, Saveetha Institute of Medical and Technical Science, Chennai-602105</institution>
        <country>India</country>
      </aff>
      <history>
        <date date-type="received" iso-8601-date="2020-08-14">
          <day>14</day>
          <month>08</month>
          <year>2020</year>
        </date>
        <date data-type="published" iso-8601-date="2020-08-14">
          <day>14</day>
          <month>08</month>
          <year>2020</year>
        </date>
      </history>
    </article-meta>
  </front>
  <body>
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    <p>
      <bold>www.ijamscr.com</bold>
    </p>
    <p>
      <bold>Prevalence and outcome of consanguineous marriage in selected community area</bold>
    </p>
    <p>
      <bold>Prof.Dr.S.KalaBarathi</bold>
      <bold>
        <sup>*1</sup>
      </bold>
      <bold>, Tamilarasi.F</bold>
      <bold>
        <sup>2</sup>
      </bold>
      <bold>, </bold>
      <bold>Thendral</bold>
      <bold> Priya</bold>
      <bold>
        <sup>2</sup>
      </bold>
      <bold>.K.S, </bold>
      <bold>Veeriayan</bold>
      <bold>Santhosi</bold>
      <bold> Kumar</bold>
      <bold>
        <sup>2</sup>
      </bold>
      <bold>, </bold>
      <bold>Vignesh</bold>
      <bold> .M</bold>
      <bold>
        <sup>2</sup>
      </bold>
    </p>
    <p>
      <italic>
        <sup>1*</sup>
      </italic>
      <italic>Principal, </italic>
      <italic>Saveetha</italic>
      <italic> College of Nursing, </italic>
      <italic>Save</italic>
      <italic>etha</italic>
      <italic> Institute of Medical and Technical Science, Chennai-602105</italic>
    </p>
    <p>
      <italic>
        <sup>2</sup>
      </italic>
      <italic>B.Sc Nursing 1V year, </italic>
      <italic>Saveetha</italic>
      <italic> College of Nursing, </italic>
      <italic>Saveetha</italic>
      <italic> Institute of Medical and Technical Science, Chennai-602105</italic>
    </p>
    <p><bold>*Corresponding Author</bold>:<bold>Prof.Dr.S.KalaBarathi</bold></p>
    <p>
      <bold>ABSTRACT</bold>
    </p>
    <p>
      <bold>Objectives</bold>
    </p>
    <p>To determine the prevalence of consanguineous marriage in our region. To identify the socio economic and demographic determinants of consanguineous marriage. To evaluate prevalence knowledge of couples of impact kind of this marriage. </p>
    <p>
      <bold>Methodology</bold>
    </p>
    <p>Quasi experiment method used to 100 samples for knowledge about prevalence of consanguineous marriage collected tools for demographic variables</p>
    <p>
      <bold>Findings</bold>
    </p>
    <p>60% knowledge for prevalence of consanguineous marriage</p>
    <p><bold>Keywords:</bold> Assess knowledge, Consangenious marriage, Demographic variables.</p>
    <sec id="sec-1"/>
    <sec id="sec-2"/>
    <sec id="sec-3">
      <title>
        <bold>INTRODUCTION</bold>
      </title>
      <p>Community health nursing relies heavily on the systematic process of designing and delivering health services and nursing care to improve the health of the entire community. Community health nursing is a specialty in nursing. According to the <bold>American Nursing Association</bold> (ANA), public health nursing is the practice of promoting and protecting the health of populations using knowledge from nursing, social and public health sciences (Waldorf, 1999). The primary goal of community health nursing is to help a community protect and preserve the health of its members, while the secondary goal is to promote self-care among individuals and families. In the health-care reform environment, the community health nurse will probably continue to care for individuals and families, particularly high-risk clients and those with communicable diseases. Community health nursing involves the identification of high-risk aggregates in the community, and the development of appropriate and workable policies and interventions to ensure accessible services for all groups of the population. Community-based nursing covers nursing care provided to individuals are delivered by health care providers.       </p>
      <p>The <bold>World Health Organization</bold> defines health as “a state of complete physical, mental and social well being and not merely an absence of diseases or infirmity”. The maintenance and promotion of health is achieved through different combination of physical, mental, and social well being together something referred to the “health triangle”. Systematic activities to prevent or cure health problem good health in humans. The term community health nursing is synonymous with public health.</p>
      <p>Consanguinity or marriage between a man and woman who are related by blood is a global health issue with a variety of distributions and occurrence rates around the world. Consanguineous marriage is defined by human geneticists as the unions of second cousins (forth degree relatives) or closer relatives. It is recently estimated that 20% of human populations live in communities with a tendency toward endogamy and globally 8.5%of all children have consanguineous parents. The prevalence of consanguineous marriage varies widely between and within countries. Although consanguinity is declined dramatically in many of western communities is still prevalent in parts of Middle-East, and India.</p>
      <p>Additionally there is a growing evidence that supports the association between parent’s consanguinity and complex, multi-factorial adult diseases in off-springs including Alzheimer’s disease, hypertension, cardio vascular disease, stroke, cancers, depression, asthma, gout, epilepsy, osteoporosis, and peptic ulcer . On the other hand consanguineous marriages are related to various social problems for families and the community including domestic violence and infertility in couples, and illicit drug abuse in children. In several studies different factors are detected as the predictors for consanguineous marriage such as socioeconomic status, educational level, location and size of the area, and people’s attitude. Better understanding of these factors can help us in implementation of appropriate interventions to prevent this health problem. Considering three main objectives</p>
      <p>It is estimated that one billion of the current global population live in communities with a preference for consanguineous marriage (Bittles and Black 2010a; Modell and Darr 2002). Consanguineous marriage is traditional and respected in most communities of North Africa, Middle East, India and West Asia, where intra-familial unions collectively account for 20–50+% of all marriages (Bittles 2011; Hamamy et al. 2011; Tadmouri et al. 2009) [Fig. 1]. Primary health care providers in communities with high consanguinity rates may be confronted by situations where they are asked to provide preconception counseling to consanguineous couples. In such countries and communities where cousin marriages are customary, many young couples nowadays present to health care providers seeking a scientifically sound answer to their questions including: “Will our children be physically or mentally abnormal?” “How can we minimize the risks for having affected children?” Reports have indicated that there may be inconsistencies in counseling for consanguinity among health care providers (Bennett et al. 1999). It is important that primary health care providers, specifically in highly consanguineous communities, have clear evidence-based guidelines in counseling a consanguineous couple to minimize their risks for having affected offspring. This review aims to portray the definition and current global trends of consanguinity, and propose simple guidelines for preconception counseling related to consanguinity based on published studies of health burden and social benefits of consanguinity. Such data could guide health care providers and help consanguineous couples take informed decisions regarding their reproductive choices.</p>
    </sec>
    <sec id="sec-4"/>
    <sec id="sec-5">
      <title>
        <bold>MATERIAL AND METHOD</bold>
      </title>
      <p>A sample of 60 were selected by convenient sampling techniques. The descriptive study was conducted during a one week period. Data collection was conducted in Nemam. After getting permission from the village panchayat. Self-structured questionnaire was used to collect data. The study investigators explained to the adults about the study’s objectives, rational and requirement of consent to participate in the study. The investigators then provided instructions for filling the questionnaire, and then guided the adults. Understanding of each question was checked by asking the adults to repeat the meaning. During the filling of questionnaires, the investigators helped throughout and helped simplifying the meaning of each question, clarifying doubts and checking for completeness of filling up the questionnaire Chi-square test was used to test the association between categorical variables.</p>
      <sec id="sec-5_1">
        <title>
          <bold>Ethical consideration</bold>
        </title>
        <p>The project has been approved by ethics committee of the institution. Informed consent was obtained from participants before initiating the study.</p>
        <list list-type="bullet">
          <list-item>
            <p>The tool consist of two groups: Group 1 and Group 2</p>
          </list-item>
          <list-item>
            <p>Section A: Part 1:  Demographic variables.</p>
          </list-item>
          <list-item>
            <p>Part 2:  Community variables</p>
          </list-item>
        </list>
      </sec>
      <sec id="sec-5_2">
        <title>
          <bold>PART1:  Demographic variables</bold>
        </title>
        <p><bold>Group 1:</bold>  Demographic data which give baseline information obtained from patients such as age, sex, Education, Occupation, religion, residence, marital status, type of family and socio economic class.</p>
      </sec>
      <sec id="sec-5_3">
        <title>
          <bold>PART 2:  Community variable</bold>
        </title>
        <p><bold>Group 1:</bold>The clients of consanguineous marriage data which gives baseline information obtained from consanguineous marriage women such as :age of marriage, type of marriage, degree of consanguineous marriage ,history of LSCS, number of birth, history of congenital defeat, history of abortion, history of prolonged labour, history of infertility,  reasons of preference, disorders, history of treatment of infertility .</p>
      </sec>
      <sec id="sec-5_4">
        <title>
          <bold>Score interpretation</bold>
        </title>
        <list list-type="order">
          <list-item>
            <p>Inadequate knowledge: 1-7</p>
          </list-item>
          <list-item>
            <p>Moderate knowledge: 8-14</p>
          </list-item>
          <list-item>
            <p>Adequate knowledge: 15-20</p>
          </list-item>
        </list>
      </sec>
      <sec id="sec-5_5">
        <title>
          <bold>Procedure for data collection</bold>
        </title>
        <p>Data collection was conducted at rural village after getting permission from the village head. The sample were collected by using purposive sampling, a total of 100 samples were selected included both married female, the self-administrated question was given and the knowledge was assessed.</p>
      </sec>
    </sec>
    <sec id="sec-6">
      <title>
        <bold>RESULT</bold>
      </title>
      <p>
        <bold>Frequency and percentage distribution of demographic variables of rural peoples at MAPEDU N</bold>
        <bold>=(</bold>
        <bold>100)</bold>
      </p>
      <table-wrap>
        <table>
          <tr>
            <td>
              <bold>S.NO</bold>
            </td>
            <td>
              <bold>DEMOGRAPHIC VARIABLES</bold>
            </td>
            <td>
              <bold>FREQUENCY</bold>
            </td>
            <td>
              <bold>PERCENTAGE</bold>
            </td>
          </tr>
          <tr>
            <td>
              <bold>1.</bold>
            </td>
            <td><bold>AGE?</bold>18-2526-3536-4545 and above</td>
            <td>424216-</td>
            <td>42%42%16%-</td>
          </tr>
          <tr>
            <td>
              <bold>2.</bold>
            </td>
            <td><bold>GENDER?</bold>MaleFemale</td>
            <td>-100</td>
            <td>-100</td>
          </tr>
          <tr>
            <td>
              <bold>3.</bold>
            </td>
            <td><bold>OCCUPATION</bold>Not workingCultivator and daily wagesOther workers</td>
            <td>363133</td>
            <td>36%31%33%</td>
          </tr>
          <tr>
            <td>
              <bold>4.</bold>
            </td>
            <td><bold>RELIGION</bold>HinduMuslimChristianOthers</td>
            <td>344620-</td>
            <td>34%46%20%-</td>
          </tr>
          <tr>
            <td>
              <bold>5.</bold>
            </td>
            <td><bold>RESIDENCE</bold>RuralUrban</td>
            <td>100-</td>
            <td>100%-</td>
          </tr>
          <tr>
            <td>
              <bold>6.</bold>
            </td>
            <td><bold>MARITAL STATUS</bold>MarriedUnmarried</td>
            <td>100-</td>
            <td>100%-</td>
          </tr>
          <tr>
            <td>
              <bold>7.</bold>
            </td>
            <td><bold>SOCIO ECONOMIC CLASS</bold>Middle classLower classUpper class</td>
            <td>374320</td>
            <td>37%43%20%</td>
          </tr>
        </table>
      </table-wrap>
    </sec>
    <sec id="sec-7">
      <title>
        <bold>BIBLOGRAPHY</bold>
      </title>
      <list list-type="bullet">
        <list-item>
          <p>Ziaei H, Jafarinasab MR, Javadi MA, Karimian F, Poorsalman H, Mahdavi M, et al. Epidemiology of keratoconus in an Iranian population. Cornea. 31(9), 2012, 1044</p>
        </list-item>
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          <p>Khaled ML, Helwa I, Drewry M, Seremwe M, Estes A, Liu Y. Molecular and Histopathological Changes Associated with Keratoconus. Biomed Res Int. 2017, 7803029. Gatzioufas Z, Panos GD, Hamada S. Keratoconus: is it a Non-inflammatory Disease? Med Hypothesis Discov Innov Ophthalmol. 6(1), 2017, 1-2. </p>
        </list-item>
        <list-item>
          <p>Jadidi K, Nejat F, Mosavi SA, Naderi M, Katiraee A, Janani L, et al. Full-ring Intrastromal Corneal Implantation for Correcting High Myopia in Patients with Severe Keratoconus. Med Hypothesis Discov Innov Ophthalmol. 5(3), 2016, 89-95. </p>
        </list-item>
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          <p>T AI, Elmor O. Intracorneal Rings (INTACS SK) Might be Beneficial in Keratoconus; A Prospective Nonrandomized Study. Med Hypothesis Discov Innov Ophthalmol. 2(2), 2013, 35-40. </p>
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          <p>Norouzpour A, Mehdizadeh A. A novel insight into keratoconus: mechanical fatigue of the cornea. Med Hypothesis Discov Innov Ophthalmol. 1(1), 2012, 14-7. </p>
        </list-item>
        <list-item>
          <p>Akkaya S. Rate of Parental Consanguineous Marriage among Patients with Visual Impairments in Turkey. Med Hypothesis Discov Innov Ophthalmol. 5(4), 2016, 115-20.</p>
        </list-item>
      </list>
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