Articles

  1. Low back pain: functional impairments, activity limitations and participation restrictions in farmers Download Article

    Shreevidya Karthik, Deepak Vishwe
    • Article Type: Research Article
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    • Pages (707-711)
    • No of Download = 107

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    Many studies have demonstrated low back pain to be one of the most frequently reported problems in farmers. But the nature of pain severity, and its affection in their day to day activity and work has not been studied in deatil so far. Method: A community based cross sectional study was conducted on 80 crop farmers with chronic low back pian,in the area of Karjat & Junnar village. A validated questionnaire for work analysis and Marathi version of “Roland Morris disability questionnaire.” were used to identify functional Impairments in farmers with Low Back Pain. Results: 55% of farmers reported having moderate intensity of pain at rest, whereas majority of farmers experienced severe (60%) intensity of pain on activity. In the Roland Morris Questionnaire 89% of the study subjects marked the responses of ‘changing position frequently to try to get my back comfortable, and ‘back is painful almost all of the time’. Conclusion: All the farmer’s low back pain increased in intensity between moderate to severe pain with activity. Majority of the study subjects reported their back to be painful almost all of the time and had to keep changing position frequently to try to get their back comfortable.

  2. A review study on traditional medicine in curing the kidney stones Download Article

    Aditya Sai Rama Krishna. K, Pharm D V Year, R. Ranjith Kumar, Pharm-D-PB(Intern)
    • Article Type: Review Article
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    • Pages (712-715)
    • No of Download = 101

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    The greatest risk factor for kidney stones is making less than one liter of urine per day. Therefore, kidney stones are common in premature infants who have kidney problems. Kidney stones are most likely to occur between the age group of 20 and 40. Different factors can increase a risk of developing a stone in the kidney. Asians are more likely to have kidney stones than African s and Americans. Sex also plays a role, with more men than women developing kidney stones, according to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). A history of kidney stones can increase your risk, as does a family history of kidney stones. Other risk factors include Dehydration, Obesity, High-protein, salt, or glucose diet, hyper parathyroid condition, Gastric bypass surgery, inflammatory bowel diseases that increase calcium absorption taking medications such as diuretics, anti-seizure drugs, and calcium-based antacids.

  3. An update on safety and efficacy of echinocandins in antifungal therapy Download Article

    Maryam Mahmoodan, Bandenawaz Ramadurga
    • Article Type: Review Article
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    • Pages (716-723)
    • No of Download = 52

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    The echinocandins are important and exciting agents because of their novel mechanism of action, low incidence of serious adverse effects, and low potential for drug–drug interactions. In vitro and in vivo, the echinocandins are rapidly fungicidal against most Candida species and fungistatic against Aspergillus species.It is also a treatment option for serious fungal infections. Pharmacokinetic–pharmacodynamic studies in animals have demonstrated superior efficacy, defined as maximal microbial kill, when compared to fluconazole. Anidulafungin exhibits a unique pharmacokinetic profile, and limited cases have shown a potential for activity in isolates with increased minimum inhibitory concentrations to caspofungin and micafungin. Caspofungin appears to have a slightly higher incidence of side effects and potential for drug–drug interactions. Micafungin appears to be very similar to caspofungin, with very few obvious differences between the two agents and also have similar safety and efficacy profile in patients with fungal infections. Adverse events are generally mild, including (for caspofungin) local phlebitis, fever, abnormal liver function tests, and mild haemolysis. Anidulafungin is economical and have dominant efficacy compared with micafungin and caspofungin in patients with candidemia and/or invasive candidiasis. All three echinocandins are generally well-tolerated. Echinocandins provide safe, uncomplicated and highly active therapy for invasive Candida infections with potentially superior efficacy versus fluconazole and better tolerability compared to formulations like amphotericin B, making them the agents of choice for moderate to severely ill patients with invasive candidiasis.

  4. Drug utilization 90% in patients with acute hemorrhagic stroke to assess adherence to standard anti-hypertensive treatment Download Article

    Girase GD, Khairnar AS
    • Article Type: Research Article
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    • Pages (724-729)
    • No of Download = 65

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    The early management of hypertension in hemorrhagic stroke affects the extent of brain injury and patient suffering’s. This study conducted at civil hospital Nashik, describes antihypertensive treatment in acute hemorrhagic stroke do not adhere to standard treatment, DU 90% not achieved. As in first 30 patients no patients were prescribed with recommended drugs, interim analysis was performed on 16% of sample size. Antihypertensive drugs were prescribed as single drug or in combination, Cap Nifedepin (40%) was most frequently prescribed single drug.. Calcium Channel Blockers were preferred with or without combination with beta-blocker agent; Mean cost per patient treated was 2280₹.

  5. Management of cross bite due to trauma in a primary tooth: a case report Download Article

    Dr. Aakash Sharma, Dr. Nanjunda Swamy K.V, Dr. Sadanand Kulkarni
    • Article Type: Case Report
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    • Pages (730-733)
    • No of Download = 53

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    The present case report describes a traumatic injury in a three year old boy. The purpose of this case report is to emphasize the importance of preserving a primary tooth in a healthy state secondary to trauma. The clinical, radiographic and therapeutic considerations are presented. The outcome of the present case report is to alert the clinician that preserving a primary tooth is a satisfactory method for treating trauma, as it adds in patient’s psychological and physical well being. Moreover it also adds in the parental satisfaction as well.

  6. Added effect of kinesiotaping on pain, range of motion and functional outcome in stage 2 peri arthritis shoulder Download Article

    Taruna Jain, Dr Snehal Ghodey
    • Article Type: Research Article
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    • Pages (734-740)
    • No of Download = 39

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    Background and Objectives In Frozen Shoulder patients have a painful loss of shoulder motion with development of dense adhesions, capsular thickening and capsular restrictions, especially in the dependent folds of the capsule. Kinesiotaping will provide support to the shoulder joint and proprioceptive stimulation helps in reducing pain by correcting the altered posture and increasing Range of Motion [6]. Pain reduction via gate control theory .incresed blood supply and thus improved nutrition [11]. The aim of the study is to find out the effect of Kinesiotaping with Conventional therapy to reduce pain, improve the shoulder range of motion and function in frozen shoulder. Materials and Method This experimental study was conducted among 30 participants who included both male and female symptomatic individuals from the age group of 40 to 60 years. Participants were randomly assigned into two groups of 15 each which included Conventional therapy (group A) and Kinesiotaping along with conventional therapy (group B) was given for 4 days. The Outcome measures were recorded pre and post 4 day of intervention using universal goniometer for shoulder Range of motion, NRS for pain and Shoulder Pain and Function Disability Scale (SPADI). Result Within group analysis showed that improved pain, range of motion and functional disability was statistically significant in both the groups (p< 0.0001) whereas between group analysis revealed that Conventional treatment along with Kinesiotaping (group B) is more effective than conventional treatment in improving range of motion and function in Frozen shoulder. Conclusion Hence, it can be concluded that Kinesiotaping along with Conventional therapy is more effective in treatment of stage 2 peri arthritis shoulder.

  7. The prevalence of infertility among outpatient department attendants in Orotta national referral maternity hospital in Asmara-Eritrea, 2007-2015 Download Article

    Ghirmay Ghebreigziabher, Kibreab Asrat, Berhane Haile, Dawit Kahsai, Ermyas Emun, Habtemariam Ghebreaman, and Natsnet Tekle
    • Article Type: Research Article
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    • Pages (741-750)
    • No of Download = 43

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    Introduction The clinical definition of infertility is a failure to achieve a clinical pregnancy after 12 months of regular unprotected sexual intercourse. The four main categories of causes of infertility well recognized in clinical practice are male infertility, female infertility, infertility in both male and female partners, and unexplained infertile couples. The objective of the study is to estimate the prevalence and describe the magnitude of identified causes of infertility based on the clinical and laboratory findings of the attendants in Orotta National Referral Maternity Hospital (ONRMH). Methodology A descriptive retrospective cross-sectional study was conducted. The sampling frame and sampling size were based on the patients’ cards of ONRMH. Ethical consideration was thought and permission was obtained from the respected bodies. Results A total of 55287 in reproductive age patients visited the outpatient department (OPD) starting 01/01/ 2007 to 31/12/2015 in ONRMH and 1547 patients were diagnosed as infertility cases. The prevalence of infertility was 2.8%. Majority (82.7%) were couples. About half (43.5%) of the attendants were between 25-34 years old. Almost all of the participants (92.4%) were married. The male factor of infertility was highest 48% followed by female factor 25%. Primary infertility (64%) was more dominant than secondary infertility. Conclusion and Recommendation This study showed that the prevalence of infertility was very low. Male factor and primarily infertility were the highest contributors. Age, sex, and year of visit were found to have significant net effect on infertility. There is a need of public sensitization to increase attendants from all zones to the infertility referral hospital.

  8. CD34 as a marker of angiogenesis in breast cancer: A study of 74 cases with brief review of literature Download Article

    Azka Anees Khan, Kiran Alam, Hasan Harris
    • Article Type: Review Article
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    • Pages (751-758)
    • No of Download = 33

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    CD34 was studied as a marker of angiogenesis in breast cancer. 74 cases of IDC were studied for this purpose. The mean microvessel density grade and the mean microvessel count per 400X field were determined for each case. Further, these 2 parameters were compared between node negative and node positive cases in order to determine whether increased angiogenesis would increase the chances of metastasis to lymph nodes. It was observed that cases with lymph node metastasis showed increased angiogenesis with a mean microvessel count and microvessel density grade of 45.6 and 2.91, respectively. In comparison, cases with absence of lymph node metastasis showed less angiogenesis and the mean microvessel count and microvessel density grade was 16.15 and 1.05 respectively. On statistical analysis, the difference between both the microvessel count and microvessel density grade for the two groups came out to be highly significant (p<0.001). Hence, increased angiogenesis was seen to lead to increased chances of metastasis to lymph nodes in our study.

  9. Successful management of esthesioneuroblastoma with chemoradiotherapy: Report of 3 cases with review of literature Download Article

    Jaspreet Kaur, Gunjesh Kumar Singh, Pragya Singh
    • Article Type: Review Article
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    • Pages (759-766)
    • No of Download = 26

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    Esthesioneuroblastoma (ENB) is a rare malignant tumour, which arises from the basal progenitor cells of the olfactory epithelium. Histopathological diagnosis is often difficult and is based on antigen detection by immunohistochemistry. The optimal treatment is still debated. Surgery followed by adjuvant radiotherapy is the recommended treatment for localised tumour, however, majority of the patients usually present in an advanced stage. We present a case series of three patients who were treated at our Institute with chemotherapy and radiotherapy between the years 2011 and 2016. Although no standard treatment protocol has been established, but combined modality therapy is the cornerstone of treatment for ENB. Chemotherapy can be added in advanced and metastatic disease. None of the patients received definitive surgical treatment. All three patients were treated by radiotherapy and chemotherapy, with endoscopic removal of the tumour done in one case. The patients were disease free during the follow-up period of 48 months, 14 months and 3 months.

  10. An interesting case of ascites – budd chiari syndrome Download Article

    Karthick Ramalingam, Mariraj I, Jagadeesan M, Mahendra Kumar K, Prasanna karthik S, Kannan R, Magesh kumar S
    • Article Type: Research Article
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    • Pages (767-770)
    • No of Download = 29

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    Budd-chiari syndrome is defined as the obstruction of hepatic veins or terminal inferior vena cava (IVC) [1-3].It is a rare disease and can be life-threatening. BCS can be classified as primary when BCS arises from a venous anomaly or as secondary, when an initial lesion is outside the veins. The incidence may be higher in Asian than western population with a slight female preponderance. Hereditary thrombophilia is a condition in which many inherited conditions leading to an increased tendency to develop venous thromboembolism (VTE). Those conditions are very rare. As such BCS is not common in these conditions [3]. In this case report we present a case of Budd- Chiari syndrome with more than one such risk factors.

  11. Ovarian Serous cystadenocarcinoma in a young woman: a rare occurrence Download Article

    Pragya Singh, Surbhi Goyal, Amit Kumar Yadav, Gunjesh Kumar Singh
    • Article Type: Case Report
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    • Pages (771-776)
    • No of Download = 25

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    Serous cystadenocarcinoma (SC) is the most common ovarian carcinoma usually affecting elderly females. Exact incidence of SC in females younger than 25 years is not known due to rarity and little available literature. We report a rare occurrence of ovarian serous cystadenocarcinoma in a young nulliparous lady of 22 years age emphasizing the fact that though unusual, possibility of SC should be kept in mind in younger age group owing to its low grade morphology, early stage at the time of diagnosis and excellent prognosis.

  12. Isaacs syndrome : A rare clinical entity Download Article

    Himanshu Juneja, Surekha Dabla
    • Article Type: Case Report
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    • Pages (777-780)
    • No of Download = 40

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    Neuromyotonia is a rare syndrome of continuous motor unit activity of peripheral nerve origin that manifests as various combinations of muscle stiffness, cramps, twitching and weakness. Isaacs syndrome is a form of acquired neuromyotonia due to an underlying autoimmune or paraneoplastic mechanism. We wish to report a case of acquired paraneoplastic neuromyotonia presented in neurology outpatient department with painful twitching of muscles all over the body for the last 6 months. While searching for an underlying cause a mass lesion was found in anterior mediastinum on radio imaging suggestive of tumor. Patient was treated with antiepileptic drugs and intravenous immunoglobulins. Tumor was removed through thoracoscopic surgery, which on histopathological examination was confirmed as thymoma. Patient responded well to treatment and after a month patient was completely asymptomatic with no fresh complaints.

  13. Effect of foot reflexolgy on dysmenorrhea among adoloscent girls in a selected nursing hostel at vijayapur Download Article

    Laxmi .B. Agnihotri
    • Article Type: Research Article
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    • Pages (781-786)
    • No of Download = 23

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    Background Dysmenorrhoea is found to be the leading cause of short term school absenteeism from 38% - 45% mentioned in different studies, 58% reported decreased daily activities and socialization 46%. In a view these facts, it was felt necessary by the investigator to give foot reflexology for dysmenorrhoea among adolescent girls and assessment of its effectiveness for reducing dysmenorrheal. Objectives The study aimed at the assessing the severity of pain and to know the effect of foot reflexologyon dysmenrrhoea, finding the association between the pre intervention intensity of dysmenorrhoea with their selected socio demographic variables of adolescent girls Materials and methods The assessment of severity of pain was done by Numerical Pain Rating Scale and is followed by administration of foot reflexology and the effect of foot reflexology was found out by using Numerical Pain Rating Scale after giving the massage. Results The pain score was high in the pre test than post test. Mean pre test pain score was 4.025 and mean post test score was 2.425 which is significantly more at p-value 2.022. Findings of the study indicated that the foot reflexology massage has an effect on dysmenorrhoea among adolescent girls. There was significant association between dysmenorrhoea and dietary pattern but there was no significant association between dysmenorrhoea and other selected socio demographic variables such as age, education, family income, age at menarche, regularity of menstruation, duration of menstrual flow, day of menstrual pain, associated symptoms of dysmenorrhoea. Conclusion The study concludes that the enhancement of health condition of adolescent girls who were suffering from dysmenorrhoea is greatly required to reduce school absenteeism, improve their academic performance and their performance at work place by giving the foot reflexology.

  14. Histopathological study of pterygium Download Article

    Dr. Radhika Mhatre, Dr. Sadhana Mahore, Dr. Rekha Khandelwal, Dr. Kalpana Bothale, Dr. Trupti Dongre, Dr. Priyamvada Sawarkar
    • Article Type: Research Article
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    • Pages (787-790)
    • No of Download = 50

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    Pterygium is a degenerative ocular disorder. The objective of this study was to determine the various histopathological changes in pterygium. Various findings such as goblet cell hyperplasia, basophilic degeneration, neovascularization, inflammatory infiltrate and dysplasia was observed. Ocular surface squamous neoplasia (OSSN) was identified in 14 out of 66 cases (21.3%). This high rate of OSSN in patients with pterygium is sufficient for the histopathological examination of all pterygium specimens so that patients can be warned of the possible recurrence of OSSN at a later time.

  15. Association between occupational exposure and hand dermatitis: a cross-sectional study in outdoor patients attending tertiary care hospital in rural background Download Article

    Dr. Yashdeep Malik,Dr. Usha Kataria, Indu Yadav
    • Article Type: Research Article
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    • Pages (791-796)
    • No of Download = 32

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    Introduction Hand eczema is common and chronic dermatological condition. It manifest in various morphological patterns related to occupational exposure of various chemicals. Aim To study the prevalence and morphological patterns of hand eczema and association with occupational exposure. Material and methods Sixty patients in age group of 15-60 years having hand eczema, attending outdoor department of dermatology were enrolled for the study. Result Prevalence of hand eczema was found to be 0.8% of total skin OPD. Commonest aggravating factors being soap and detergents in housewives (66%) followed by cement in labourers (53%) crop harvesting in farmers (45%). Conclusion Majority of patients had moderate effect on quality of life (DLQI Score 6-10) due to hand eczema.

  16. Isolated peritoneal metastasis creating confusion in carcinoma cervix – A case report and review of literature Download Article

    Dr. Gunjesh Kumar Singh, Dr. Pragya Singh
    • Article Type: Review Article
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    • Pages (797-803)
    • No of Download = 26

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    Carcinoma cervix commonly spreads locally and through lymphatic channels. Peritoneal metastasis (PM) is an extremely rare entity. We present a case of a 35-years-old female with carcinoma cervix, who presented with bleeding per vaginum along with pelvic pain and posed diagnostic confusion on contrast enhanced computed tomography (CECT). To the best of our knowledge, till date only two similar cases of carcinoma cervix with PM have been reported in the literature.

  17. Nutrease powder - nature’s blend of nutrients for optimal health energy and longevity in old age people Download Article

    GovindShukla, NagalakshmiYaparthy, NehaGiri, C.J. Sampath Kumar
    • Article Type: Research Article
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    • Pages (804-814)
    • No of Download = 20

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    An old Age individual needs to balance energy intake with his or her level of physical activity to avoid storing excess body fat. Dietary practices and food choices are related to wellness and affect health, fitness, weight management, and the prevention of chronic diseases such as osteoporosis, cardiovascular diseases, cancer, and diabetes. The over-sixties make up the fastest growing segment of the population in most countries. Although life expectancy has also increased dramatically over the last 100 years, this segment of the population is susceptible to many health risks from a poor diet. Evidence from various sources indicates that many older people fail to get the amounts and types of food necessary to meet essential energy and nutrient needs. There are numerous reasons why older people might not be getting the most nutritious diet Assessment of nutritional status is essential for preventing or maintaining a chronic disease and for healing. Knowing the causes of changing nutritional needs and dietary preferences is needed to understand a patient’s nutritional status. This review summaries the current available scientific literature regarding the effect of NUTREASE POWDER, The Nature’s blend of protein, Fibers, plant extracts (phytochemicals) as balanced Nutrition for old Age Persons.

  18. To compare immediate effect of static and dynamic stretching on sprint and jump performance in healthy school children Download Article

    Shraddha Date, Dr. Snehal Chincholkar, Dr. Anuradha Sutar, Dr. Snehal Ghodey
    • Article Type: Research Article
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    • Pages (815-822)
    • No of Download = 24

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    The aims of this study were to compare the immediate effects of stretching static and dynamic stretching on sprinting and vertical jump performance of healthy school children. Ninety healthy school children (mean age = 11 yrs, range8–15 yrs) were randomly assigned into three groups: Static(SS), Dynamic (DS) and control group(NS) pre- and post-treatment immediately tests were performed to examine the effects of stretching on 10 m sprint run(10SR), Sargent vertical jump test (VJH). Following the warm-up period, subjects immediately began their stretching program. Subjects performed 5 sets of static (30 sec on alternate leg 2 repetitions) in (SS) and dynamic stretching (20 sec on alternate leg 10 repetitions) in (DS); in the control condition they do not performed stretching. Results from one way ANOVA revealed a significant difference on 10m sprint test (p<0.0307). Static stretching hindered 10SR and VJH by 1.07% and 1.3% respectively, Dynamic stretching improved 10SR and VMJ by 6.7% and 1.31% respectively, in control group 10SR and VMJ hindered by 4.5% and 4.55% respectively. In conclusion, the use of dynamic stretching is preferable for its immediate effect on jumping and sprint performance in healthy school children.

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