Articles

  1. An evaluation of tear film and ocular surface changes in type 2 diabetes mellitus Download Article

    AarthiPanneerselvam, KanmaniKothandaraman, Srinivasan Gopalan
    • Article Type: Research Article
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    • Pages (607-612)
    • No of Download = 74

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    Aim To compare tear film changes and ocular surface abnormalities in diabetics with that in non-diabetics. Materials & methods In this prospective case control study 100 eyes of 50 patients with Type 2 diabetes and 100 eyes of 50 normal patients were compared. All the patients were subjected to tear assessment tests- Schimers tests, Tear break up time tests in addition to Corneal sensitivity tests, CCT and CIS. Conclusion Our study showed that In Diabetics CCT was 560.14(SD 15.65) and Non diabetics was 534.14(SD 44.50) p value < 0.005.Corneal sensitivity measured by Cochet-Bonnet esthesiometer in diabetics was 26.08+/- 5.14mm and in Non diabetics was 53.58+/-2.06mm(p value <0.001).Tear break up time in diabetics was 6.8 +/-7.01 sec and in non-diabetics was 12.8+/-5.71sec(p value< 0.001).Total secretion by Schimers test was 7.77+/-3.9mm and basal secretion was 13.4+/-5.7mm(p value<0.001) . Conjunctival impression cytology revealed squamous metaplasia in diabetics as 1.25+/-0.63mm and in non-diabetics 0.65+/-0.57mm .Goblet cell density in diabetics was 429.68+/-108.35 cells/mmsq and in non-diabetics was 545.17+/-77.56cells/mmsq. Therefore diabetic patients with poor metabolic control and diabetic retinopathy should be assessed for tear film and ocular surface changes.

  2. Potential sources and effects of work-stress: an overview Download Article

    Maha Abdul-Moniem Mohammed El-Amin, Purna Singh A
    • Article Type: Research Article
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    • Pages (613-616)
    • No of Download = 58

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    Individuals are affected at one time or another by work-related stress. Stress at work is very common in modern lifestyle; and it is different for various people which have touched almost all professions. Here we review the possible causes and consequences of works stress to suggest the researchers to concentrate on these areas to develop adequate stress management strategies.

  3. Prevalence of anemia in type 2 diabetics-an overview Download Article

    Prabakaran Thamilmani, Kannan Rajendran, Rajendran K
    • Article Type: Research Article
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    • Pages (617-623)
    • No of Download = 86

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    Aim Anemia is found to contribute to the development and progression of micro and macro-vascular complications of diabetes. This study aimed to determine the prevalence of anemia in patients with diabetes and the occurrence of micro and macro vascular complications in them. Methods This was a retrospective study of 227 patients with diabetes regularly followed up as outpatients for one year. Patient's demographic profile, history of stroke, ischemic heart disease (IHD), and concomitant hypertension (HT) along with the most recent values of complete blood picture and renal function tests were collected from the database of the Hospital. Results The prevalence of anemia in our study population is 55.5%, which is two to three times more common as compared to the result from previous studies. Anemia was six times more common (53.9%) compared to the previous study for the same GFR value (GFR > 60 mL/min/1.73 m2) and half of them in stage one kidney disease. Conclusion Anemia is a common accompaniment with diabetes and it is seen early even in the absence of renal impairment which necessitate early screening of anemia and further studies to know the possible etiology.

  4. Stone quarry of the eye Download Article

    AarthiPanneerselvam, KanmaniKothandaraman, PrabakaranTamilmani
    • Article Type: Research Article
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    • Pages (624-627)
    • No of Download = 65

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    A female child aged 8yrs presented with history of extrusion of small stone like particles from her lateral canthal region with minimal congestion, irritation and tenderness in her left eye for the past 1 month. Local antibiotics and anti inflammatory drugs did not improve the condition. Imaging tests were inconclusive because of periodic expulsion of the stony particles. Thehistopathological results were suggestive of amorphous material organized in lamellae, which confirmed the diagnosis of dacryolith. As the stone particles were spontaneously and periodically extruded, most probably through a ruptured duct to the conjunctival surface at the palpebral area, no active immediate intervention was contemplated. We are presenting this case because of the rarity and interest and hype associated with it.

  5. Failure of mini implants in orthodontics – A literature review Download Article

    Dr Jeevan M. Khatri, Dr. Saba Anjum Siddiqui, Dr. Gaurav Tated
    • Article Type: Review Article
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    • Pages (628-632)
    • No of Download = 90

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    Obtaining satisfactory clinical results in orthodontic treatment requires adequate mechanical control, which includes anchorage control. Hence it is thought that temporary anchorage devices (mini implant) could provide a good solution for that problems that are encountered in conventional techniques. The aim of the review is to analyse available literature on mini implant in orthodontics and analyse factors associated with failure of implant.

  6. Ultrasonography in orthodontics: Review article Download Article

    Dr Jeevan M. Khatri, Dr Parikshit Agrawal
    • Article Type: Review Article
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    • Pages (633-639)
    • No of Download = 76

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    Recent development of the ultrasonography (US) equipments enables the visualization of fine detail of the surface structure of the face and neck soft tissue. This review article deals with studys which were carried out to determine the thickness of masseter muscle and its relation with various dentofacial pattern. It also include assessment of temporalis muscle and tongue function and movement during swallowing.

  7. A comparative study to assess the knowledge regarding environmental pollution among rural and urban people in Bangalore with a view to develop information guide sheet Download Article

    Ms. Subhashini G Rajarajeswari
    • Article Type: Research Article
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    • Pages (640-646)
    • No of Download = 60

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    The environment is everything around us and the quality of our life depends heavily on the quality of our environment. Environmental pollution is one the biggest problem the world faces today. It is an issue that troubles and economic, physical of our lives. The contamination of environment is also being linked to some of the disease that are currently1. The aim of the study is to assess the knowledge regarding environmental pollution among rural and urban people. A sample of 100 adults were conveniently selected out of that 50 from rural 50 from urban. An information guide sheet was developed emphasizing the various components like air pollution, water pollution, noise pollution, soil pollution was given to participants and their relatives.

  8. Study on appropriate and rational drug use in hypertensive patients with other comorbid diseases Download Article

    Shivashankar Velu, Alfatih Khalil, Pheba Susan Thomas
    • Article Type: Research Article
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    • Pages (647-652)
    • No of Download = 167

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    Hypertension is one of the major chronic diseases resulting in high mortality and morbidity worldwide. It is a leading risk factor for coronary heart disease, stroke and chronic renal disease. There are many classes of antihypertensive available. Rational prescribing is essential as hypertension is highly prevalent and therapy is chronic. Health care professionals need to utilise limited resources wisely in order to provide effective, safe and affordable antihypertensive therapy. The objective of the study is to determine the appropriateness and rationality of antihypertensive drugs in the selected study population as per our inclusion criteria. The data were collected from regular ward rounds and they were analysed. The appropriateness was analysed using the JNC-7 guidelines. A total of 97 patients were included in our study, their prescriptions were analyzed. The age categorization reveals that majority of patients were above 40 years. The analysis of risk factors associated with hypertension shows that 33 (34.02%) patients were smokers, 30 (34.39%) patients were alcoholics and 36 (37.11%) patients were found to be with BMI >30. The total numbers of antihypertensive drugs prescribed in the study population was found to be 156. It was found that β-blockers were the most commonly prescribed in 41 (26.28%) patients, followed by CCBI (Dihydropyridines) in 33 (21.15%) patients. The total numbers of inappropriately prescribed drugs were found to be 29 (18.59%) and they were found to be prescribed in contraindicated co-morbid conditions. Among the inappropriately prescribed drugs 11 (37.93%) drugs of ACE inhibitors were found to be contraindicated in renal failure patients, 9 (31.03%) diuretics were contraindicated in dyslipidaemic patients, 6 (20.69%) beta blockers were contraindicated in asthmatics and 3 (10.34%) ARB’s were contraindicated in patients with renal failure & hyperkalemia. The rationality of prescribed drugs was analyzed; the results reveals that 138 (88.46%) drugs prescribed were found to be rational and 18 drugs (11.54%) prescribed were irrational. The irrational prescription drugs were analyzed and it was found that 8 (44.44%) prescriptions contain drugs from same class, 6 (33.33%) with increased frequency of dose and 4 (22.22%) prescription with over dose. The results reveal continuous monitoring of the prescribing of antihypertensive agents by the clinical pharmacist is necessary to resolve the issues of inappropriateness and enhancement of rational prescribing. The clinical pharmacist has the greater responsibility in monitoring of hypertensive patients with other co-morbid conditions.

  9. Food safety from farm to plate make food safe Download Article

    Dr. Karandeep Singh Sandhu, Dr. Nidhi Gupta, Dr. Ramandeep Kaur Sohi, Dr. Preety Gupta, Dr. Shivani Sharma, Dr. Surbhi Jindal
    • Article Type: Research Article
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    • Pages (653-658)
    • No of Download = 82

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    Food safety is a scientific discipline describing handling, preparation, and storage of food in ways that prevent foodborne illness. This includes a number of routines that should be followed to avoid potentially severe health hazards. Food safety considerations include the origins of food including the practices relating to food labeling, food hygiene, food additives and pesticide residues, as well as policies on biotechnology and food and guidelines for the management of governmental import and export inspection and certification systems for foods. Food can transmit disease from person to person as well as serve as a growth medium for bacteria that can cause food poisoning. In developed countries there are intricate standards for food preparation, whereas in lesser developed countries the main issue is simply the availability of adequate safe water, which is usually a critical item.

  10. Role of lekhanbasti in raktgatsnehavriddhi (hyperlipidaemia) Download Article

    Dr.Snehal V. Kukade, Dr.Vaidehi V.Raole, Dr.VivekDhongdi, Dr.ShashankChoudhary
    • Article Type: Research Article
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    • Pages (659-662)
    • No of Download = 82

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    Hyperlipidemia is a condition in which the levels of lipoproteins [cholesterol, triglycerides (TGs), or both] are raised in the plasma, which can be co-related to raised “Raktagatsneha” (lipids) in the body. Hyperlipidemia is contributed by high fat diet, sedentary lifestyle, etc., These causative factors can be compared to Snigdha, Guru, PicchilaGunasevana, and Chesthadvesha (lack of exercise), which lead to SantarpanjanyaVyadhis (diseases produced by overnutrition) according to Ayurveda. So ApatarpanaChikitsamore specific, “Lekhana” (emaciation/desiccation) is the treatment which can remove abnormally increased Sneha.Basti is indicated in all strotogatvyadhi. Thus lekhanBastiis useful inRaktgatsnehavriddhi (hyperlipidaemia).

  11. Heat of a moment takes life of innocent own kid- A rare case report Download Article

    GauravSharma, Dinesh Chhillar, Vijay Pal Khanagwal, S.K.Dhattarwal, Sunil Narwal, Deepshikha
    • Article Type: Case Report
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    • Pages (663-667)
    • No of Download = 77

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    Murder, domestic violence, child abuse, rape and other crimes are daily headlines nowadays. These crimes have been integral part of our social structure since the inception of human existence and find place in all religious books too. Economical, political & sociological factors are relevant in explaining the root causes for these disasters but at the heart of all the crimes are people. Most extreme form of human relationships gone wrong is seen when any crime is committed against children. Children are vulnerable, dependent and easy targets for adults. More so, it is difficult to imagine that primary care givers i.e. parents can be part of heinous crime against their own children. Through this case report we will discuss in detail a case from rural Haryana, where an alcoholic man kills his own son because he was not given his dinner at time, by his wife. Till this date, wife used to be battered by him but it was a sad end for the kid that night.

  12. Sex determination by osteometric analysis of sternal end of fourth rib in haryanvi population Download Article

    Jai Prakash Soni, S.K. Dhattarwal, Suresh Kantha Rathee
    • Article Type: Research Article
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    • Pages (668-674)
    • No of Download = 74

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    Background Sex is a very important identification point, since mainly there are two sexes: Male or Female. Generally, skull and pelvic bones are dimorphic but when these bones are not available ribs can act as a dimorphic bone to predict sex. Aim and Objectives Sex Determination by Osteometric Analysis of Sternal End of Fourth Rib in Haryanvi Population. Material and Method The specimen consisting of fourth ribs were collected from 50 males and 50 females during the year 2014 to 2015 at the Forensic department of Pt. B. D. Sharma Postgraduate Institute of Medical Sciences Rohtak Haryana, India. The samples were divided into young and old age group. Superior–inferior height (SIH), anterior–posterior width (APW) and pit depth (PD) of the sternal end of fourth rib were taken. Results The correct sex determination in younger and older age group was 84.65% and 81.75% respectively. Conclusion The result demonstrated that SIH and APW were highly dimorphic in all group while PD was dimorphic in older age.

  13. Lost bet kills man in undignified manner-A rare case report Download Article

    Gaurav Sharma, Vinod Mehra, Luv Sharma, Deepshikha, S. K. Dhattarwal, Pankaj Chhikara
    • Article Type: Case Report
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    • Pages (675-678)
    • No of Download = 76

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    Every human being lives for food, comforts, sex and prestige. Exceptions are rare, who believe in dictum of “vanity of vanity, all is vanity’’. Since long men have been known to have more interest in firearms, vehicles, games involving bets etc. than women, but in rural India, this fascination coupled with long standing loan intricacies, involvement of families and issue of prestige can be a deadly combination, waiting to explode at the slightest argument. Murder is the most serious form of human relationship gone wrong. Homicides exclusively due to ano-genital trauma have not been widely reported and most of these rare cases have been reported in children and females due to perverted sexual practices like fisting. Through this paper, we present a case report of a thirty five year old male cab driver, who had purchased a car in installments from friends. When he was told to pay the last ten thousand rupees, he under the influence of alcohol preferred to have a wooden rod shoved up his anus than to pay. He was mercilessly beaten before a rod was forcefully inserted in his anal canal. He was operated upon for anorectal injuries and given highest level of treatment but died four days later. We will discuss the case in detail and emphasize the need of proper history taking, inter-departmental co-ordination and meticulous autopsy.

  14. A study of worsening renal function during therapy of cardiovascular disease and assessment of its prognosis Download Article

    Thomas Zacharia, Anju Joseph, Anu J, Anu Philip, Aswathy Jai Kumar
    • Article Type: Research Article
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    • Pages (679-688)
    • No of Download = 140

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    Background and Aims Cardiovascular disease is a class of diseases that involves the heart, the blood vessels or both. In patients with cardiovascular diseases, with reduced renal perfusion, it is common to encounter worsening of renal function during the hospital stay. This study was carried out to identify worsening renal function in patients with cardiovascular disease from their renal parameters and to assess the prognosis of the disease in the study population. Methods and Results This observational study conducted over a 6 month period found that at presentation, the major diagnosis was Hypertension (96.77%) with the majority of the drugs given to the patients being Anti Hypertensive (16%). Eighteen patients (29.5%) showed Worsening Renal Function. To these patients, Aspirin and Clopidogrel, two nephrotoxic drugs were prescribed during both therapy and discharge. Interactions such as Atorvastatin vs Pantoprazole (25.80%) and Ceftriaxone vs Furosemide (16.12%), both of which can worsen the renal function were identified. Conclusion It can be concluded that worsening renal function occurs frequently among hospitalized cardiovascular patients and that clinical characteristics available at hospital admission can be used to identify both the predictors and the patients at increased risk for worsening renal function.

  15. Antihyperglycemic and hypoglycemic effect of portulaca quadrifida linn Download Article

    Vijayarangan Sivasamy, Manivannan Ekambaram, Kothai Ramalingam, Arul Balasubramanian
    • Article Type: Research Article
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    • Pages (689-692)
    • No of Download = 65

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    The hypoglycemic effect of ethanolic extract of Portulaca quadrifida was investigated on glucose loaded and streptozotocin induced diabetic rats. The blood glucose levels were measured at 0, 1, 2 and 3 h after the treatment. The ethanolic extract of P. quadrifida (200 mg/kg) reduced the blood glucose of normal rat from 85.331.79 to 65.173.67 mg/dl, 3 h after oral administration of the extract (P<0.001). It also significantly lowered blood glucose level in streptozotocin induced diabetic rat from 330.673.27 to 132.174.49 mg/dl, 3 h after oral administration of the extract (P<0.001). The antihyperglycemic activity of P. quadrifida was compared with tolbutamide, an oral hypoglycemic agent.

  16. A case report on augmentin (amoxicillin/ potassium clavunate) induced acute generalized exanthematous pustulosis Download Article

    Dr. Suresh Sake, Dr. N V Sudheer, Dr. C Sugunakar Raju, Dr. Nara Prasad P. Mohammed Shafi, M. Venkata Subbaiah
    • Article Type: Case Report
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    • Pages (693-697)
    • No of Download = 87

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    Acute Generalized Exanthematous Pustulosis (AGEP) is a rare and severe cutaneous reaction whose etiology is most often drugs. Spontaneous resolution is observed in most patients. Augmentin [Amoxicillin/ potassium clavunate] is an uncommon cause of AGEP. A 42-year-old male patient presented with severe AGEP due to Augmentin [Amoxicillin/ potassium clavunate] treatment prescribed for common bacterial infections.

  17. Assessment of prescribing pattern in coronary artery disease Download Article

    Battu Rakesh, Dr. B.S. Suresha, Jaladi Himaja, Emilda.T.Joy, Angitha Rose Varghese
    • Article Type: Research Article
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    • Pages (698-715)
    • No of Download = 183

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    Background Cardiovascular disease is the leading cause of death and disease burden globally. In recent years, India has become a country with the largest number of cardiovascular disease patients. Dyslipidaemia in the patients with diabetes has been shown to increase the risk of coronary heart disease. There is a much larger burden and overall medical costs on coronary artery disease itself. Study of drug-prescribing pattern can give insight into the trends in using the drugs in coronary artery disease in treating their co-morbid conditions. The knowledge of prescription pattern can lead us toward the rational drug use and help to take measures to improve prescribing habits. Multimorbidity is common in old age. Deaths associated with cardiovascular events remains constant in many countries due to new therapeutic approaches for prevention and treatment of cardiovascular diseases. This condition is widely attributable to unhealthy outcomes in its association with risk factors such as Hypertension, Diabetes mellitus, smoking, alcohol consumption and sedentary lifestyle which play a significant role in the progression of cardiovascular diseases. Objectives The objective of this study was to evaluate the coronary artery disease prevalence and drug utilization pattern in the department of general medicine in a tertiary care hospital in Karnataka, India. Study design A Cross Sectional study was carried out in the General Medicine Department, MIMS Teaching Hospital, Mandya, Karnataka, using a well-designed patient data collection form. Results In this study, among 99 cases of coronary artery diseases analysed, which consists of male n=60 (60.6%) and n=39 (39.4%) were females. The incidence of CAD was more common in male compared to female. In this study two different type of coronary artery disease were identified which includes 33 Angina Pectoris patients and 66 Myocardial infarction (MI) patients. Most of the patients diagnosed with coronary artery disease were of the age group of 41-60 (55.55%). The most common co-morbid conditions were hypertension in 10 (10.10%) and a combination of hypertension, diabetes, dyslipidaemia 42 (42.42%) patients. The prescription pattern of various cardiovascular drugs were found to be as – antiplatelet drugs 99 (100%), anti-hyperlipidemic drugs 81 (81.81%) antibiotics 87 (87.87%), anti-anginal drugs 33 (33.33%), antihypertensives 42 (42.42%), anticoagulants 35 (35.35%), diuretics 65 (65.65%) and bronchodilators 57 (57.57%). The average number of drugs per prescription was found to be 7.34 and the percentage of drugs prescribed by generic name was found as 24.20%. The most commonly prescribed drug classes in coronary artery disease were antiplatelet drugs followed by antihyperlipidemics and antibiotics. This was followed by anti-anginal drugs, antihypertensives and anticoagulants. The prescribing pattern could be improved by reducing the number of drugs per prescription and by prescribing generic drugs to reduce the economic burden of the patients. Conclusion Uncontrolled DM, Hypertension, Hyperlipidaemia risk factors for developing coronary artery disease. Anti-thrombotic followed by Statins, antidiabetics and antihypertensive were most prescribed drugs. Combinations of drugs were prescribed to the patients for effective therapy. The present study will help the healthcare professionals to optimize the efficient and safe use of cardiovascular drugs.

  18. Formulation and invitro evaluation of bucco adhesive bi layer tablets of eprosartan Download Article

    G. Anuhya Goud, Kolikapogu Suvarna roja, G. Venkataih, Dr.A. Yasodha, A.Sivakumar
    • Article Type: Research Article
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    • Pages (716-726)
    • No of Download = 78

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    Eprosartan buccoadhesive bilayered tablets containing bioadhesive layer and drug free backing layer were formulated to release the drug for extended periods of time with reduction in dosing frequency. The tablets were prepared by direct compression method using bioadhesive polymers like Carbopol 934p, Magnesium stearate and Hydroxy propyl cellulose alone or in combination, Ethyl cellulose has incorporated as an impermeable backing layer. Tablets were evaluated for weight and content uniformity, thickness, hardness, surface pH, swelling index, invitro drug release and invitro drug permeation. The modified invitro assembly was used to determine and compare the bioadhesive strength of tablets all characteristics of formulated tablets were shown to be dependent on composition of bioadhesive materials used. Maximum bioadhesion strength was observed for tablets formulated with Carbopol 934P.

  19. Severe upper gastrointestinal bleeding with gastric ulcer and anaemia secondary to prolonged use of aspirin and clopidogrel – A case report Download Article

    Ambed Mishra, Pramod Kumar A, Krishna Undela, Dileep Kumar P
    • Article Type: Case Report
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    • Pages (727-730)
    • No of Download = 227

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    A combination therapy of aspirin with clopidogrel is useful in the prevention of various disorders of cardiovascular system, secondary prophylaxis thrombosis of systemic to pulmonary artery shunts, acute ST-segment elevation myocardial infarction and percutaneous coronary intervention. Traditionally, aspirin has been used for such conditions alone. Clopidogrel is as an alternative choice for aspirin. While the combination therapy shows a better outcome, but also has been associated with risks. Upper gastrointestinal bleeding (UGIB) is one such known adverse effect caused by fibrinolytic therapy, but it normally subsides itself without any treatment and is rarely serious, where the patient requires intensive care and monitoring during hospitalization. And, ulcers are the most common cause of hospitalization for UGIB. Anaemia can be seen in UGIB patients due to ulcers induced by the aspirin plus clopidogrel therapy. Here, we report a serious case of UGIB, gastric ulcer and anaemia in a 66-year-old male patient with structural valve deterioration and stent and upon long term use of combination therapy of aspirin and clopidogrel.

  20. Non-Hodgkins lymphoma (DLBCL type) of extranodal site: A rare case report Download Article

    Dr.Suresh Iyer, Dr.Pragati Karmarkar, Dr.Kalpana Bothale, Dr.Anjali Patrikar Dr.Sadhana Mahore
    • Article Type: Case Report
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    • Pages (731-736)
    • No of Download = 108

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    Non-Hodgkins lymphoma (NHL) are heterogenous group of neoplastic disorder of lymphoid tissue. It can occur as primary lymph node disease or at extranodal sites. Extra-nodal sites of involvement can be gastrointestinal tract, lung, thyroid, salivary glands, skin and female genital tract. We report a rare case of extra-nodal Non-Hodgkins lymphoma in a 40 year old female who presented with pain and swelling in abdomen. She was admitted due to a finding of a large retroperitoneal tumor in the lower abdomen and pelvis with a heterogenous appearing uterus which on histopathology and immunohistochemistry turned out to be diffuse large B cell lymphoma. She then received medical management, as is appropriate for this diagnosis. Chemotherapy was initiated in a very timely manner and she showed significant improvement within weeks.

  21. Comparative study of topical versus peribulbar anaesthesia in phacoemulsification cataract surgery Download Article

    Srinivasan Gopalan, Aarthi Panneerselvam
    • Article Type: Research Article
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    • Pages (737-742)
    • No of Download = 94

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    Aim To compare and evaluate patients discomfort and complications during phacoemulsification and implantation of foldable intraocular lenses under topical and peribulbar anesthesia in cataract. Materials and methods In this comparative study a total of 200 patients who underwent phacoemulsification with intraocular lens (IOL) implantation were included. Patients were randomly assigned under Topical anaesthesia (group 1, n=100) and Peribulbar anaesthesia (group 2, n=100). Results Group 1 ,2% had no movements and 51% had no movements.14% of group 1 and 34% of group 2 patients exhibited slight movements .47% of group 1 and 14% of group 2 had moderate movements.37% of group 1 and 1% of group 2 exhibited full movements. Mean value of group 1:2.21, SD: 0.78 and mean value of group 2:0.69,SD:0.84. Conclusion Topical anaesthesia is an effective alternative to peribulbar anaesthesia for phacoemulsification reducing the risks associated with peribulbar injection.

  22. Antimicrobial studies of leaves and flowers extract of Cassia fistula linn Download Article

    Dr. S. Kannan, Shelsia Shaji, Shilpa K Joy, Shivasadat Mousavi, Shahida M.P, Mohamad Sabeeh
    • Article Type: Research Article
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    • Pages (743-746)
    • No of Download = 72

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    The Cassia Fistula Linn. Plant (family:Leguminosae; sub-family: caesalpiniaceae) a very common Indian plant known for its medicinal properties with safe and without any side effect. The plant is used in folk medicines for tumor of the abdomen,glands,liver and throat cancer.It also helps in curing leprosy,skin diseases, and syphilis.Ayurvedic medicines recognized for its carminative and laxative property.The plant native to tropical Asia is also known as Indian Laburnum,yellow flower.The research aims to analyse the antibacterial, antifungal property of the plant. Performed the preliminary phytochemical studies the constituents like tannins, flavonoids, and glycosides were found out. The antibacterial activity with the total ethanolic extract of leaf and flower of Cassia Fistula Linn.were tested against four pathogenic bacteria and two fungi by using the standard well plate method. To studies is conducted by using organisms like Gram negative (E.coli, pseudomonas Aeruginosa) Gram positive (StaphyloccousAureus, Bacillus Subtills) and fungi (Candida Albicans, Aspergilus Niger) were used. The antimicrobial studies were conducted using different concentration of the total ethanolic extract of Cassia Fistula Linn. which shows good antibacterial and moderate antifungal activity.

  23. Effectiveness of raltegravir in combination with Atazanavir/Ritonavir and Lamivudine as secondline ART- A case report Download Article

    Gururaja KS, Mothi SN, Sudheer AP, Swamy VHT, Shyam S, Srirama BR, Pramod Kumar A
    • Article Type: Case Report
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    • Pages (747-749)
    • No of Download = 46

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    Increase in the number of people being initiated on Anti retroviral therapy, there is inevitably an increase in the number of people failing first-line therapy. The choice and rationale for selection of second-line therapy is limited. Constructing a second line regimen is a challenge for patients who have been exposed to all classes of NRTI’s in resource poor settings. The combination of Raltegravir with boosted atazanavir is a viable option if proved effective in trials with sufficient statistical power. We report a case of 48 week follow-up data of a patient started on Boosted atazanavir with Lamivudine and Raltegravir as secondline.

  24. Viruddhahara and its role in formation of disease Download Article

    Dr. Samir Sapcota
    • Article Type: Research Article
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    • Pages (750-753)
    • No of Download = 81

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    Viruddha Ahara are those food articles which is composed of substances having no affinity at all and which vitiates the Doshas (Morbid Humors) but do not eliminate them from our body. They are of 18 types of Viruddha Ahara. In my article I also described 20 food articles and there preparation which are best among wholesome and unwholesome by nature. Pathogenesis of Viruddha Ahara and its role in manifestation different disease is also mentioned here, and also about Factors pacifying the ill effect of Viruddha Ahara.

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