Articles

  1. Study the levels of specific biochemical markers and correlating the radiological findings in chronic kidney disease patients Download Article

    Varun Prasanna R, Rama Krishna Rao M
    • Article Type: Research Article
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    • Pages (405-413)
    • No of Download = 355

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    AIM To study the changes in serum calcium, serum phosphorus, serum PTH levels and vitamin D levels in chronic renal failure patients. Study the bone changes on X-ray in cases of chronic renal failure. Find out the prevalence and nature of skeletal involvement in chronic renal failure and to associate the severity of skeletal involvement with the duration of chronic renal failure. Associate the biochemical profile changes and bone changes on x-rays and find their significance. MATERIALS 50 Stage III chronic kidney disease patients who are under conservative management as well as Dialysis, meeting the Inclusion and Exclusion criteria are selected. Patients who are getting admitted as well as attending outpatient department in Rajah Muthiah Medical College & hospital. Patients with chronic kidney disease of stage 3 and above. Patients on both conservative management & on dialysis. Both male & female patients. Patients presenting with acute kidney injury. (serum creatinine rises by ≥ 26µmol/L within 48 hours). No previous calcium, phosphate binder, vitamin D supplementation. Not more than 5 years on dialysis. Age >65 years. METHODOLOGY 50 patients of previously diagnosed chronic kidney disease of stage 3, stage 4 and stage 5 and patients on chronic dialysis who are meeting the inclusion and exclusion criteria are selected. Necessary investigations are performed and the proforma is filled with the values for each patient. CONCLUSION Out of 50 CKD patients, 35 (70%) patients had x-ray changes depicting skeletal abnormalities. Low calcium levels were found in majority of patients. High Phosphorous levels were found predominantly. High Parathyroid hormone levels were found predominantly. Low Vitamin D levels were found in majority of cases. KEY WORDS: Chronic Kidney disease, Parathyroid hormone, Vitamin D, Serum Calcium, Serum Phosphorous.

  2. A Study on the Prevalence of Multiple Postural Deformities among the School Children Download Article

    Dr. Preeti Sharma
    • Article Type: Research Article
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    • Pages (414-418)
    • No of Download = 371

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    METHODOLOGY Samples were twelve hundred school children studying in different regions (Greater, Inner and Outer) of Himachal Pradesh. The age of the children were ranging from 11-15 years. The selected paired deformities were Kyphosis-knock knee, kyphosis-bow legs, kyphosis-flatfoot, Knock knee- flat foot and bow leg-flat foot. The data was analysed by employing descriptive statistical tool. RESULTS AND FINDINGS Results of the study revealed that fifty five (55.08) percent of school children in Himachal Pradesh were having paired postural deformities. It was also found that the Greater Himalayan (54.64%) region was the most affected region followed by Inner (48.25%) and Outer Himalayan (20.83%) region. On further analysis, it was found that the combination of kyphosis and knock knee i.e. kypho-knock knee was most prevalent in Inner (13.75%) Himalayan region than the other two regions of Himachal Pradesh. Regarding this pair of deformity, male children showed the maximum number (8.38%) of percentage in comparison to females. Data was further analysed to see the pairing of kyphosis and flatfoot, the results revealed that outer (15.21) Himalayan region was most affected and the majority of the prevalent cases were in males (12.59) than the female children. The next analysis showed that kypho-bow legs pair of multiple deformity were more prevalent in Outer Himalayan regions (14.71) and males (16) were found to be on higher side of numbers than their counterparts. Results of the study also showed that the cases knock knee-flat foot among male and female children in different regions of Himachal Pradesh is more or less same or with a marginal difference, thereby we can say that this pairing of deformity has equally affected the children irrespective of their gender and regions they belong. The last pairing was of bow leg-flat foot for which the results showed that the number incidences were quite higher in outer Himalayan (22.94%) region than the other. Male children (19.26) were found more deformed for this combination of deformity in comparison to females. CONCLUSION On the basis of analysis of data and results found, it can be concluded that the multiple postural deformities were highly prevalent among school children of Himalayan region. Bow leg-flatfoot was found to be the most affecting paired deformity among the children of Himachal Pradesh.

  3. Evaluation of cardiac autonomic neuropathy in diabetes mellitus using electrocardiographic changes and ANSiscope device Download Article

    Arun Kumaran P, Rama Krishna Rao M
    • Article Type: Research Article
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    • Pages (419-425)
    • No of Download = 383

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    AIM Evaluation of cardiac autonomic neuropathy in diabetes mellitus. Patient using electro cardio graphic changes of heart rate variability and correlate the ECG changes with beat to beat variation using ANSiscope device. MATERIALS STUDY POPULATION 50 diabetic patients attending Diabetology Outpatient Department, of RMMCH, Chidambaram. These subjects were selected after scrutinizing them for exclusion criteria. 50 patients attending General Medical Outpatient Department at RMMCH, Chidambaram. These subjects were age matched controls. METHODOLOGY After selecting the patients on basis of the criteria history will be elicited and clinical examination done as per proforma. The necessary investigations [fasting blood sugar, post prandial blood sugar, ECG, ANIscope] will be done and statistically analyzed. CONCLUSION The resting heart rate (86.16±7.6) was significantly (P<0.05) higher than that of non diabetic controls (76.64±9.18). There was a leftward deviation of QRS axis among diabetics (31.6°) as compared to controls (54°). QTc interval was prolonged (400.62 ± 32.18 msec) in diabetic study population which was significant (P0.0000). Cardiac dysautonomia was demonstrated in the study population using the following parameters. Abnormal E:I ratio (<1.1) (50%). Postural fall in systolic blood pressure (>10mmHg) (42%) Ratio of 10th RR interval to 5th RR interval was abnormal in (60%). Dyansys ANSi scope score was abnormal in 80% of the study group.

  4. Mystery of burnt bride and circumstances of death - A Case Report Download Article

    Dr. Dinesh Chhillar, Dr. Luv Sharma, Dr. Kunal Khanna, Dr. Jai Prakash Soni, Dr. Vincent Merry, Dr. Vinod Kumar
    • Article Type: Case Report
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    • Pages (426-430)
    • No of Download = 416

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    A scene of crime report helps a lot in autopsy examination. This is part of information, which should be provided with the other inquest papers of a case. In common practice, investigating officer collects this report after the post mortem report. Not only he considered scene of crime report as an unnecessary part of investigation, but also it is not given by the investigating member of the forensic science laboratory team before autopsy examination. A keen investigation officer keeps all the concerned details in his mind and prepares a parallel report of crime scene with the help of drawing and photographs. We report a case of partially burnt female with fatal pressure on the neck and stab injury to the abdomen. A 27 year old newly married woman was found dead in forest near a village. A partially burnt female and a knife with burnt handle were discovered at the scene. Blood stains and broken pieces of ornaments were found around the body and on nearby surrounding region. Autopsy revealed a stab injury to the abdomen extending to the small and large intestine and ligature strangulation at the neck with post mortem burns.

  5. A prospective epidemiological study of comorbid conditions in psoriasis Download Article

    Yasodhara P, Prasad P.V.S, Kaviarasan P.K.
    • Article Type: Research Article
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    • Pages (431-443)
    • No of Download = 208

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    AIM 1. To determine the prevalence of diabetes, hypertension, obesity in psoriatic patients and controls. 2. To determine the abnormal lipid parameters and serum uric acid levels in psoriatic patients and in controls 3. To determine the prevalence of metabolic syndrome and cardiovascular disease in both psoriatic patients and control population. 4. To determine the association of psoriasis with diabetes, hypertension, lipid abnormalities, obesity, cardiovascular disease and metabolic syndrome. MATERIALS The study comprised 100 cases of psoriasis and 100 controls visiting the inpatient and outpatient Department of Dermatology at Rajah muthiah medical college & hospital. All clinically diagnosed cases of psoriasis of more than 18 yrs. Patients who are willing to undergo the laboratory investigations and those who give consent for the study. Patients taking systemic drugs for diabetes, hypertension & cardiovascular diseases for the past 3 months and those who are under control. Pregnant and lactating women METHODOLOGY A prospective clinical case control study, with 100 patients of psoriasis and 100 controls were undertaken to know the prevalence of diabetes and hypertension in cases and controls and the incidence of abnormal lipid parameters, metabolic syndrome and cardiovascular disease CONCLUSION Patients had increased prevalence of diabetes, hypertension, hypertriglyceridemia, metabolic syndrome when compared to controls. A correlation was found between the severity of the disease and diabetes mellitus, hypertension, hypertriglyceridemia and metabolic syndrome. However no correlation was found between psoriasis and serum uric acid levels, obesity and cardiovascular disease.

  6. Vitamin D status and its association with blood glucose parameters among Indian diabetic patients: A non-interventional, cross-sectional, observational study Download Article

    Praveen Raj, Rahul Balip, Kamlesh Patel, Vishal Vaidya
    • Article Type: Research Article
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    • Pages (444-450)
    • No of Download = 330

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    INTRODUCTION The aim of the study was to evaluate vitamin D status and its association with blood glucose parameters in Indian diabetic patients. MATERIALS AND METHODS This cross-sectional, non-interventional, single visit program was conducted across 236 sites in India where 4434 (males: 2580; females: 1854) diabetic patients of 18-65 years of age who had undergone testing for vitamin D and blood glucose in the last 3 months were recruited in the study. Anthropometric and metabolic parameters, and serum 25-hydroxyvitamin D (25[OH] D) was measured. The patient was said to have ‘non-optimal level of vitamin D’ if had serum 25(OH) D <30 ng/mL (‘vitamin D deficient’ <20 ng/mL, ‘vitamin D insufficient’ 20-29 ng/mL) and was said to have ‘optimal level of vitamin D’ if the level was ≥30 ng/mL. Descriptive statistics was used in the study. RESULTS 99.0% patients had type 2 diabetes and 1.0% patients had type 1 diabetes mellitus. 81.7% of the patients had ‘not optimal’ level of 25(OH)D where 41.5% patients had 25(OH)D deficiency and 40.2% patients had 25(OH)D insufficiency and 18.3% of the patients had ‘optimal’ level of 25(OH)D. Mean level of 25(OH)D was 22.1 ± 7.9 ng/mL. Higher proportion of patients with ‘not optimal’ level of 25(OH)D had a higher range of fasting plasma glucose (FPG; 135-298 mg/dL), glycated hemoglobin (HbA1c; 8.3-13.8%), and postprandial glucose (PPG; 217-299 mg/dL) as compared to patients with ‘optimal’ level. In addition, a negative correlation was found between 25(OH)D levels and calcium and a positive correlation with height and body mass index. CONCLUSION Despite an ample amount of sunlight in the country, 81.7% of Indian diabetic patients had deficient or insufficient levels of vitamin D (25[OH]D <30 ng/mL). The level of vitamin D had a negative correlation with FPG, PPG, HbA1c and serum calcium; suggesting that vitamin D supplementation may improve glycaemic control in diabetic patients.

  7. Cardiac rupture in a blunt trauma of chest: A case report Download Article

    Dr. Vinod Kumar, Dr. Dinesh Chhillar, Dr. Vincent Merry, Dr. Jai Prakash Soni, Dr. S.K. Dhattarwal
    • Article Type: Case Report
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    • Pages (451-454)
    • No of Download = 290

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    Road traffic accident (RTA) is a major epidemic of non-communicable disease in present-day scenario. Many people die, become handicap or bed-ridden for the rest of their lives due to RTA. Death due to RTA is unnatural; so these kinds of cases come for autopsy. Among the cases that are brought to the postmortem room for autopsy, RTA cases form a big part of it. Any part of the body gets injured in RTA, for example - brain, cervical spine, lungs, heart, abdominal viscera or bones. Deaths due to brain injury are very common in RTA but blunt trauma of the heart leading to cardiac rupture is not commonly seen. We report a case of cardiac rupture due to blunt trauma of heart in a road traffic accident.

  8. An antioxidant therapy - To maintain optimum health and wellbeing Download Article

    Govind Shukla, Sangeeta Kumari, Dr. Vinod Yadav, Dr. DS Pandaulia, Dr. NS Gaur, Marlon O. Perez, Mercedita H. Perez
    • Article Type: Research Article
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    • Pages (455-462)
    • No of Download = 231

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    Antioxidants are our first line of defense against free radical damage, and are critical for maintaining optimum health and wellbeing. The need for antioxidants becomes even more critical with increased exposure to free radicals. Pollution, cigarette smoke, drugs, illness, stress, and even exercise can increase free radical exposure. Because so many factors can contribute to oxidative stress, individual assessment of susceptibility becomes important. Antioxidants terminate the chain reactions by removing free radical intermediates, and inhibit other oxidation reactions. They do this by being oxidized themselves, so antioxidants are often called as reducing agents such as thiols, ascorbic acid or polyphenols. Antioxidants are widely used as ingredients in dietary supplements and have been investigated for the prevention of diseases such as cancer, coronary heart disease and even altitude sickness. Many experts believe that the Recommended Dietary Allowance (RDA) for specific antioxidants may be inadequate and, in some instances, the need may be several times the RDA. As part of a healthy lifestyle and a well-balanced, wholesome diet, antioxidant supplementation is now being recognized as an important means of improving free radical protection. Damage to cells caused by free radicals is believed to play a central role in the aging process and in disease progression. The present paper Reviews the Role of Antioxidants in maintaining optimum health and wellbeing.

  9. Study on prescribing pattern of diuretic agents and occurrence of abnormal electrolyte levels among cardiovascular disease patients in a private corporate hospital Download Article

    Shivashankar V, Mera George
    • Article Type: Research Article
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    • Pages (463-466)
    • No of Download = 296

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    Diuretics are used extensively in hospitals and in community medical practice for the management of cardiovascular diseases. A prescription monitoring study for diuretic drugs was undertaken in the cardiology department of a 700 bedded private corporate hospital. The purpose of this study was to investigate the prescribing patterns of diuretics in CVDs patients and assess the abnormalities in electrolyte levels due to diuretic use. Prospective observational study of 9 months duration was undertaken from December 2014 to August 2015. A total number of 133 patients with various CVDs disorders were enrolled in the study. The utilization pattern of diuretic evaluated, loop diuretics were most widely used in patients with CVDs. Electrolyte abnormality in diuretic users were analysed, it was found that 36.09% patients were having hypokalemia followed by hyperkalemia, hyponatremia, hypochloremia. Patients with hypokalemia were categorized into three groups based on potassium level. The results reveal that 48.37% patients were having mild hypokalemia 20.38% were with moderate hypokalemia and 31.25% patients were with severe hypokalemia. The statistical evaluation signifies the association between the age and hypokalemia. The rate of prevalence of hypokalemia was found to be more when the age increases. The present study demonstrated the positive impact on diuretic management and pharmaceutical care in cardiovascular disease patients. The elderly populations are more affected abnormality by diuretic therapy, monitoring of potassium levels in the elderly population was a major factor to reduce the adverse events.

  10. Diagnosis Of Dhatura Poisoning: A Comparative Study Of The Signs And Symptoms As Per Ayurvedic And Modern Classics Download Article

    Dr. Bishnu Choudhury, Dr. Amit Swarnakar
    • Article Type: Research Article
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    • Pages (467-471)
    • No of Download = 244

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    The incidence of Dhatura poisoning is not uncommon. It can occur accidentally due to chewing of the seed with rice or other eatables. Previously accidental exposure to this poison was more when the plant was available abundantly. But now the availability of this plant is gradually reducing but the incidence of its use as hallucinogen is increasing. Dhatura or “Road Poison” is surreptitiously used with betel leaf, tea etc. to rob travellers as it stupefies the person. The victims are commonly rescued from the roadside in a semiconscious state. They can recall only some parts of the incident that had happened. Diagnosis of Dhatura poisoning, as per the Modern texts, can be done basing upon the 9Ds (9 signs and symptoms started with “D”). In Ayurvedic Classics i.e. in Charaka and Susruta Samhita, there is no discussion regarding the signs and symptoms of Dhatura poisoning. Astanga Sangraha/ Hridaya and some Nighantus (Pharmacopoea) discussed on the point which may be taken as criteria for diagnosis of Dhatura poisoning.

  11. Radiologic technology students’ technical skills in simulation and actual chest X-ray imaging as measured by competency evaluation: Indicative of radiologic technologists’ supervisory performance Download Article

    Marlon O. Perez, Atty. Tomas A. Sajo, Mercedita H. Perez, Dr. Elvira L, Arellano, Dr. Puritan P. Bilbao, Dr. Shirley R. Jusayan, Dr. Maria Zeny L. Loquiano, Govind shukla, Sangita kumari
    • Article Type: Research Article
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    • Pages (472-482)
    • No of Download = 326

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    This study sought to determine the relationship of radiologic technology students’ level of competency in cognitive skills, affective skills, and psychomotor skills and further find out if these variables were significantly determinants of their technical skills in chest x-ray imaging. This inquiry likewise sought to measure the relationship of students’ technical skills in simulation and actual chest x-ray imaging. The results showed that the levels of competency of students’ cognitive skills, their affective skills, and their psychomotor skills were determined to be competent. The overall mean scores in determining the levels of competency of students’ technical skills in simulation, and actual chest x-ray imaging, were also determined to be competent. There was a significant relationship between students’ cognitive skills and affective skills. A significant correlation was also determined between students’ cognitive skills, and psychomotor skills. There was a significant correlation between students’ technical skills in simulation and actual chest x-ray imaging. The students’ affective skills, their psychomotor skills, and their cognitive skills in the aspects of radiographic positioning, image quality, and radiographic anatomy identification, were found to be significant determinants of their technical skills in chest x-ray simulation. The students’ affective skills were found to be the best determinants of their technical skills in the performance of actual chest x-ray imaging.

  12. Brain damage - Post-operative complication of cardiac bypass surgery Download Article

    Srija Poreddy, Dr.Prabhu Thilak, Ch.Madhava Reddy, H Srinivas, N Sriram
    • Article Type: Review Article
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    • Pages (483-487)
    • No of Download = 377

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    Bypass surgery and angioplasty are probably the most over performed surgeries in the world today. Because of the present lifestyle of people of this era day by day the cases of cardiac surgeries are increasing up the number. Recent recognition of brain damage as a consequence of heart bypass surgery has led to many recent investigations. Dementia and cognitive defects are the most common cases observed in the patients who have undergone bypass surgeries. Microembolisation and inadequate perfusion are found to be the etiological factors of brain damage. With the recent technological development we can easily diagnose the extent of brain damage. As the incidence of cardiac bypass surgeries can't be reduced there is a need to prevent the consequential brain damage occurred. Vasodilators corticosteroids etc., have been used to prevent brain damage in patients undergoing bypass surgery. In the coming era, with the new advancements in technology, one can hope to build a sure safe heart bypass surgeries.

  13. Study of working of outdoor patient department (OPD) in a setup of rural back ground hospital of northern India Download Article

    Dr. Usha Kataria, Dr. Dinesh Chhillar
    • Article Type: Research Article
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    • Pages (488-496)
    • No of Download = 301

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    It is submitted that Health is a priority agenda of the state. Our emphasis is to provide quality health care to the community, especially the underserved and under privileged segment of the society, at an affordable cost. Outdoor patient department (OPD) acts as a window to hospital services and a patient’s impression of the hospital begins at the OPD. This impression often influences the patient’s sensitivity to the hospital and therefore it is essential to ensure that OPD services provide an excellent experience. It is also well establish that 8-10% of OPD patient need hospitalization.[1] It should be well organized to avoid confusion and frustration and also regulate the flow of inpatients to the hospital. This research study was designed with the intention of generating feedback information in functioning of OPD of the selected general hospital in providing patient’s satisfaction. Also for the effective functioning of OPD, the opinion of both patient and consultants are of immense importance for any organization.

  14. Fracture-dislocation of cervical vertebra in a case of accidental strangulation by chunni: A case report Download Article

    Dr. Vincent Merry, Dr. Dinesh Chhillar, Dr. Jai Prakash Soni, Dr. Vinod Kumar, Dr. S.K Dhattarwal
    • Article Type: Case Report
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    • Pages (497-500)
    • No of Download = 302

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    Accidental ligature strangulation in adults though uncommon, is occasionally reported amongst agricultural workers working adjacent to machinery and circumstantial evidence alone sufficiently indicates the accidental nature of the occurrence. While it is recognized that fracture and dislocation of the cervical vertebra are seen in judicial hanging or hanging associated with a long drop, it is not routinely reported in ligature strangulation. In the present case, a 48 year-old female was accidentally strangled while she was working in the field by the side of a crop thrasher when her chunni accidentally got stuck (from behind) in the thrasher belt, pulling her towards it by the neck thereby strangling her. She became unconscious & while being brought to the hospital, she expired on the way. The autopsy revealed fracture and dislocation of the 5th cervical vertebra with extensive bruising of the deep muscles of the neck and fracture of greater horn of hyoid bone apart from the ligature mark around the neck. Fracture and dislocation of the cervical vertebra in accidental ligature strangulation by chunni is a rare occurrence and not reported routinely in cases of accidental strangulation.

  15. Reverse pharmacology “A new outlook in the drug development process” Download Article

    Agnesh. Valluri
    • Article Type: Research Article
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    • Pages (501-504)
    • No of Download = 754

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    The pharmaceutical industry has historically seen an Incredible growth primarily due to the discovery of blockbuster drugs with the potential to generate over 1 billion US $ sales , however recent trends indicate that this model may no longer lead to high growth rates . The industry is really facing a major challenge to sustain and grow. Drug discovery and development process involves a 10- 15 years of investigation period and investments between US $1 billion and $ 1.5 billion. This resulted in “Target Rich Lead Poor” performance. The world health organisation’s commission on Intellectual property and Innovation in public health has also duly recognised the promise and role of traditional medicine in drug development for affordable health solutions .In this scenario Reverse pharmacology plays a vital role and can be defined as the integrating science of developing candidate drugs from a clinical to experiential hits and leads by transdisciplinary exploratory studies to understand the mechanisms of action at different pathological stages of biological organism . Then, confirm candidate drugs from experimental to clinical use on the basis of safety, efficacy and acceptability on relevant science potentiating fast track drug discovery and development of safer and effective drugs. India being a pluralistic health care system offers immense opportunities for natural product drug discovery and development based on traditional knowledge and clinical observations.

  16. Comparative study of sandhigata vata described in ayurveda in relation to osteoarthritis Download Article

    Tapashi Borah, Amit Swarnakar, Ruma Dey, B.K. Bharali
    • Article Type: Research Article
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    • Pages (505-509)
    • No of Download = 666

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    Ayurveda, the complete life science has given special emphasis to the functional aspect of vayu. Due to the prokopana of vayu due to asatmya aahara and vihara different kinds of disease occurs in the human body and sandhigata vata is one among them. The clinical features attributed in Ayurveda clearly relates to the features described by modern counterparts in relation to osteoarthritis. The aim of the article is to discuss the features described in Ayurveda regarding sandhigata vata in relation to osteoarthritis.

  17. A study on drug utilisation evaluation of HMG -CoA reductase inhibitor (atorvastatin) in a tertiary care teaching hospital Download Article

    M. Praveen Kumar, K. Bhanu Prasad, Y. Manasa, Ayesha Siddiqua, Mubeen Ul Hasan, Faheem
    • Article Type: Research Article
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    • Pages (510-520)
    • No of Download = 636

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    OBJECTIVES: Our objectives are to determine the safety, efficacy, rationale use of Atorvastatin in patients in a tertiary care teaching hospital and to provide information to health care providers and patients. METHODOLOGY: It was a prospective observational study which was undertaken in medicine, ICU and casualty departments of 300 bedded multi- speciality tertiary care teaching hospital, SVS hospital, for a period of 6 months. A total of 210 prescriptions were included in the study and were followed for the drug use evaluation to study. This study criterion was the in-patients and out-patients of age greater than 18yrs of either gender who are prescribed with HMG-CoA reductase inhibitor Atorvastatin. RESULTS: The drug was found to be more safe in males (97.24%) compared to females (93.85%). The drug was found to be more effective in females (98.46%) compared to males (96.55%).The drug was found to be rationally prescribed more in males (95.86%) compared to females (92.31%). In the lipid profile study, all the different parameters like serum cholesterol, High density lipoproteins (HDL), Low density lipoproteins (LDL), Very Low density lipoproteins (VLDL) and triglycerides were found to be in the normal range in about 60-70% of males, where as lipid profile parameters of females were found to be in the normal range in about 20-30% females. CONCLUSION: We conclude that the drug use was found to be safe, effective and it was rationally prescribed. Interventions for promoting more appropriate use of Atorvastatin should be implemented. Further studies from time to time are required in drug utilization pattern and standard treatment guidelines to be circulated among practicing physicians.

  18. Lagerstroemia speciosa – A review Download Article

    Dr. Bishnu Choudhury, MD (Ay), Ph.D.,
    • Article Type: Research Article
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    • Pages (521-524)
    • No of Download = 737

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    Herbal medicines are used traditionally throughout the world since long time. Recent data estimated that 80% of the world population till depends in herbal medicine. Lagerstroemia speciosa (popularly known as Queen’s Flower/ Pride of India) one of the useful medicinal plants, abundantly available in North Eastern part of India, Burma, Bangladesh, Philippines, Malaysia etc. Lagerstroemia speciosa also known as ‘Ajhar’ in Assam (India) is traditionally used by the people of Assam for curing Diabetic Mellitus (Madhumeha) since long time and getting optimum benefit. In Bhavaprakash Nighantu also (Ayurvedic classic of 16 century) mentioned Lagerstroemia speciosa as hypoglycemic drugs. It has been used as a folk medicine among people with diabetes in Bangladesh & Philippines. It is a deciduous, tropical, flowering tree of Lythraceae family. Flowers are showy, pink to purple color. The active principles of this plant which act as insulin like action are Corosolic Acid and lagerostromin.

  19. Pediatric autoimmune neuropsychiatric disorders associated with Streptococcal infections (PANDAS) – A review Download Article

    Nausheen afsar, Loan Gh. Mohammad, C.Revathi, N.Sriram, Sadaf fatima
    • Article Type: Research Article
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    • Pages (525-531)
    • No of Download = 437

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    PANDAS are a rare disease in children which shows the relationship between group A beta hemolytic streptococcal infection with rapid onset of obsessive compulsive disorder and tic compulsive disorder. It has been proposed that children with PANDAS experience tics, obsessive-compulsive behavior, and perhaps other neuropsychiatric symptoms as an autoimmune response to streptococcal infection. This includes information on symptoms, pathophysiology, diagnosis and treatment about PANDAS. Molecular mimicry hypothesis proposed mechanism for the PANDAS. Five main diagnostic criteria are proposed for identifying PANDAS. Treatment includes medicinal treatment along with experimental therapy which involves environmental modifications, stress management, infection control etc. On the basis of current information available PANDAS remains yet unproven hypothesis.

  20. Chronic calcific pancreatitis and pd stenting - A case report Download Article

    Ramoju Kishore Kumar, N. Sriram, Vanga Ramesh, Madhav Reddy, C.Revathi, M.Sunil Kumar
    • Article Type: Case Report
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    • Pages (532-534)
    • No of Download = 558

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    A Chronic calcific Pancreatic is the rare and most often associated with chronic pancreatitis condition. Here we present case of a 16 year old boy who presented in hospital with a severe abdominal pain a pancreatic type since 3 months. No history of jaundice, GI bleed, vomiting, altered bowel habits, fever, shortness of breath, decreased urine output or altered sensorium. He had been having repeated attacks of similar but milder upper abdominal pain. This time however the pain was terrible. USG abdomen showed chronic calcific pancreatitis with dilated PD and multiple intra ductal calculi, no peripancreatic edema or fluid collection and small GB polyp was seen. He underwent ERCP showed dilated, irregular pancreatic, duct with ecstatic side branches. Pancreatic sphincterotomy done, few soft protein plug extracted PD stent placed

  21. Ethno-zoological aspects in Ayurveda (Part 1) Download Article

    Dr. Juban Kharkongor, M.D. (Ayu), Dr. Amit Swarnakar, M.D. (Ayu)
    • Article Type: Research Article
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    • Pages (535-540)
    • No of Download = 416

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    Ayurveda in its domain has hidden many treatment modalities in different kinds of ailments that the present human being is suffering from. These treatment modalities are subjected to high quality research basis and are incorporated in various texts of Ayurveda. The acharyas of ayurveda had known that the future humans will suffer from such kinds of ailments that only medicinal herbs will not be sufficient to eradicate the disease process. For that reason they took the help of ethno-zoological way of treatment modalities and incorporated in the preparation of different kinds of medicinal preparations. In this article, taking this in mind, a few diseases along with its treatment by the use of animals and animal products is taken into account.

  22. Ethno-zoological aspects in ayurveda (Part 2) Download Article

    Dr. Juban Kharkongor, M.D. (Ayu), Dr. Amit Swarnakar, M.D. (Ayu)
    • Article Type: Research Article
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    • Pages (541-550)
    • No of Download = 367

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    Ayurveda in its domain has hidden many treatment modalities in different kinds of ailments that the present human being is suffering from. These treatment modalities are subjected to high quality research basis and are incorporated in various texts of Ayurveda. The acharyas of ayurveda had known that the future humans will suffer from such kinds of ailments that only medicinal herbs will not be sufficient to eradicate the disease process. For that reason they took the help of ethno-zoological way of treatment modalities and incorporated in the preparation of different kinds of medicinal preparations. In this article, taking this in mind, a few diseases along with its treatment by the use of animals and animal products is taken into account.

  23. Crocin (acetaminophen) induced toxic epidermal necrosis: A rare case report Download Article

    Bushrah Anjum .B, Roshan Jameel.B, Javeed Baig.M, Sravanthi.D, Asif .SK, Ganesh Reddy.V, Venkata Subbaiah.M
    • Article Type: Case Report
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    • Pages (551-554)
    • No of Download = 631

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    Acetaminophen is a mostly preferable drug for the treatment of analgesic and antipyretic. The main mechanism of action is acts on hypothalamus to produce antipyretic effect and act peripherally to block pain impulse generation, also inhibits prostaglandins synthesis in central nerve system. Toxic epidermal Necrosis (TEN) commonly termed as idiosyncratic reactions to drug. It is a serious and life threatening adverse drug reaction. Here, we report a case of TEN in a patient who developed the lesion after oral administration of CROCINE ACTIVE (ACETAMINOPHEN). These drugs have rarely been concerned in this disorder. The suspected drug in this case was ‘Crocin Active (500mg)’. The patient was managed with antibiotics, corticosteroids and parenteral fluids and topical safromycine. Almost all various drugs induced dermatological disorders toxic epidermal necrosis and Steven Johnson syndrome is a key role in terms of mortality. Promptly recognition of that condition, withhold the drug and immediately send to hospital then provide appropriate treatment its play a vital role for reducing mortality.

  24. Antibacterial activity of ethanolic leaf extract of Kalanchoe pinnata and its application in the treatment of abscess caused by staphylococcus aureus Download Article

    B.Deepthi, K.Shivakanth Reddy, Y.Keerthi Reddy, L.Sushma, A.Shambashiva Rao
    • Article Type: Research Article
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    • Pages (555-558)
    • No of Download = 785

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    In this study we have found anti-bacterial activity of ethanolic extract of leaves of Kalanchoe pinnata against microbial flora organism staphylococcus aureus which was measured as parameter of activity which was compared against std. drug amoxicillin antibiotic. The plant extract shows potent zone of inhibition than the std. compound. Leaf extract of chloroform & water showed mild zone of inhibition compared to that of ethanolic extract. Aim of study was to extract the constituents from leaves of Kalanchoe pinnata & to explore anti-bacterial activity against staphylococcus aureus using disc diffusion method & with the obtained results we have concluded that the ethanolic extract can be used in treatment of abscesses because of its potency against staphylococcus aureus.

  25. Habit of television viewing and its impact on behavior among school age children Download Article

    Ninganagouda G Patil. Dr Anuradha Maske
    • Article Type: Research Article
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    • Pages (559-567)
    • No of Download = 510

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    Background Television viewing is became easily available source for entertainment especially for school going children. This entertainment source produces a high impact on children behavior. Aims and objectives The study aimed at assessing television viewing habits of school age children in order to know its impact on the behavior of children, finding the correlation between habit of television viewing and behavior of school children and find out the association between television viewing habit scores and behavior scores with selected demographic variables. Materials and methods Television viewing habits of school age children was assessed by rating scale and used interview method for data collection. Behavior was identified by using the rating scale. Results The study results shows that 72.41% of school age children had average television viewing habits, 25.86% had poor and 1.72% good habit. Regarding behavior 91.37% children had average behavior, 3.4% of children had poor and 5.17% had average behavior. The correlation value shows that 0.64 as positive correlation between television viewing habits with behavior of school age children. There was a significant association between television viewing habits scores with age of the child (X2=7.52, df=2), occupation of father (X2=8.21, df=2), number of TV in the Home (X2=4.04, df=1) and behavior scores with type of family (X2=15.81, df=1). Conclusion The study concludes that improves the television viewing habits among school age children and reduces its negative influence over children behavior.

  26. CRITICAL ANALYSIS OF GRIDHRASI (SCIATICA SYNDROME) Download Article

    Dr. Bishnu Choudhury
    • Article Type: Review Article
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    • Pages (568-571)
    • No of Download = 974

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    One of the most common diseases that affect the hip and the lower limbs is Sciatica. In sciatica there is pain in the distribution of sciatic nerve which begins from buttock and radiates downwards to the posterior aspect of thigh, calf and to the outer boarder of foot. There is often history of trauma, continuous lifting of heavy objects, prolonged working in forward bending position etc but in many of the cases the actual causative factor remains unknown. Improper sitting posture, over stress, jerking movement during travelling & sports may worsen the condition which causing significant threat to working population. The ancient knowledge of this disease is analyzed here and an attempt has been made to understand the ancient knowledge of Ayurveda in respect of etiology, clinical feature, prognosis and management in current practice. “Sciatica Syndrome” is a condition described in modern medicine is resembles with Gridhrasi which results from irritation of the greater sciatic nerve by displaced tissue, commonly a prolapsed intra vertebral disc, and other changes may be osteophytes, secondary fibrosis, tumor, or due to injury. The disease Gridhrasi is a Vataja Nanatmaja Vyadhi described by almost all the ancient Ayurvedic Scholars. The cardinal signs and symptoms of Gridhrasi are Ruka (pain), Toda (pricking sensation), Stambha (stiffness) and Muhuspandana (twitching) in the Sphika, Kati, Pristha, Uru, Janu, Jangha and Pada in order and Sakthikshepa Nigraha i.e. restricted lifting of the leg. This disease is successfully managed by Ayurvedic Medicine and Panchakarma therapy.

  27. Restoring orthodontically mistreated anterior quadrant using non rigid connector Download Article

    Neha Choudhary
    • Article Type: Research Article
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    • Pages (572-575)
    • No of Download = 584

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    The excessive flexing of the long-span fixed dental prosthesis, which varies with the cube of the length of span, can lead to material failure of fixed dental prosthesis or to an unfavorable response. Tooth movements in divergent directions create stresses that are transferred to the abutments and cause failure of the weaker retainer. Non rigid connectors transfer shear stresses to supporting bone and permits abutments to move independently. This clinical report describes the prosthodontic management of an earlier orthodontically mistreated patient with edentulous span on both sides of a pier abutment, with a fixed partial denture having a non-rigid connector.

  28. Work stress in nurses of causality department Download Article

    Mohd Imtiyaz Shaikh, Varsha N. Mane, Shakeel Ahmed, Prabha V, Danasegaran M, Pradeep Kumar Vegi
    • Article Type: Research Article
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    • Pages (576-579)
    • No of Download = 277

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    The present study was undertaken to assess stress levels in nurses of causality department. The present cross sectional study was conducted at causality department of GEMS hospital. A total of 20 willing female nurses were included in the study after obtaining voluntary, written, informed consent. Questionnaire was designed with the help of existing literature and suggestions from experts and administered to the participants. Questionnaire contains 29 questions which includes demographic factors, general factors, individual factors, organizational factors, extra organizational factors. Nursing care plays a crucial role because they are the providers and put the patient care plan prescribed by the physicians in action. The increased pressure of modern day living can lead to a greater number of physical and mental problems. Hence it is essential to learn how to deal with stress in a positive way to make nursing profession stress free. The present study helps to understand the level of stress in nursing professionals and highlights implementation of stress management programs at hospitals.

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